clomipramine has been researched along with Body Weight in 23 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This double-blind controlled study examines the impact of clomipramine when taken by an anorexia nervosa population, refeeding in hospital, over and above that generated by the established treatment programme." | 9.05 | Hunger, food intake and weight: the impact of clomipramine on a refeeding anorexia nervosa population. ( Crisp, AH; Lacey, JH, 1980) |
| "Long-term treatment with clomipramine (CMI), a tricyclic antidepressant, induces food craving and body weight gain in patients." | 7.74 | Effect of chronic treatment with clomipramine on food intake, macronutrient selection and body weight gain in rats. ( Calegari, L; Gentil, V; Gorenstein, C; Nunes-de-Souza, RL; Planeta, CS, 2007) |
| " In this study we have examined the impact of clomipramine on food and activity in anorectics engaged in a treatment programme enabling them to regain normal body weight." | 7.67 | Clomipramine and 'drive' in people with anorexia nervosa: an in-patient study. ( Crisp, AH; Crutchfield, M; Lacey, JH, 1987) |
| " Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern." | 5.07 | Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993) |
| "This double-blind controlled study examines the impact of clomipramine when taken by an anorexia nervosa population, refeeding in hospital, over and above that generated by the established treatment programme." | 5.05 | Hunger, food intake and weight: the impact of clomipramine on a refeeding anorexia nervosa population. ( Crisp, AH; Lacey, JH, 1980) |
| " During and at the end point of the chronic stress experiment, food consumption, body weight, adrenal gland, thymus and spleen indices, behavior scores, sucrose consumption, and stress hormone levels were measured." | 3.78 | Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression. ( Chen, T; Jia, W; Jia, Z; Jiang, T; Lin, J; Qiu, Y; Su, M; Wang, X; Xie, X; Zeng, C; Zhao, A; Zhao, T; Zhou, M, 2012) |
| " Caffeine in a dose of 100 mg/kg body weight enhanced the recovery of the prednisolone-suppressed HPA axis significantly." | 3.68 | Caffeine enhances the speed of the recovery of the hypothalamo-pituitary-adrenocortical axis after chronic prednisolone administration in the rat. ( Abou-Hashim, EM; Blijd, JJ; de Jong, FH; el-Kannishy, MH; Lamberts, SW; Marzouk, HF; Uitterlinden, P; van Koetsveld, P; Zuyderwijk, J, 1991) |
| " CMI significantly reduced food intake and body weight gain, but did not alter either adrenal weight or basal serum corticosterone levels." | 3.67 | Previous chronic chlorimipramine treatment did not modify some physiological responses to acute and chronic stress in rats. ( Armario, A; García-Marquez, C; Giralt, M, 1988) |
| " In this study we have examined the impact of clomipramine on food and activity in anorectics engaged in a treatment programme enabling them to regain normal body weight." | 3.67 | Clomipramine and 'drive' in people with anorexia nervosa: an in-patient study. ( Crisp, AH; Crutchfield, M; Lacey, JH, 1987) |
| "Mianserin (60 mg daily) was compared with chlorimipramine (150 mg daily) in the treatment of 145 depressed in- and outpatients in four centres." | 2.65 | A double-blind multicentre trial comparing the efficacy and side-effects of mianserin and chlorimipramine in depressed in- and outpatients. ( Barres, M; Blum, A; Charbaut, J; Israel, L; Kammerer, T; Molczadzki, M; Pinder, RM; Rigaud, A; Stulemeijer, SM, 1980) |
| "Clomipramine-treated animals had shifts in the laterality of monoamines in limbic regions with lower serotonin levels on the right side while vehicle-treated animals had lower serotonin on the left side." | 1.31 | Differences in behavior and monoamine laterality following neonatal clomipramine treatment. ( Andersen, SL; Dumont, NL; Teicher, MH, 2002) |
| "Patients treated with four dosage regimes of clomipramine (Anafranil) 10 mg t." | 1.26 | An investigation into the short-term effects of clomipramine (Anafranil) administered in low doses, on weight. ( Beaumont, G, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (65.22) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qin, D | 1 |
| Chu, X | 1 |
| Feng, X | 1 |
| Li, Z | 1 |
| Yang, S | 1 |
| Lü, L | 1 |
| Yang, Q | 1 |
| Pan, L | 1 |
| Yin, Y | 1 |
| Li, J | 1 |
| Xu, L | 1 |
| Chen, L | 1 |
| Hu, X | 1 |
| Wang, X | 1 |
| Zeng, C | 1 |
| Lin, J | 1 |
| Chen, T | 1 |
| Zhao, T | 1 |
| Jia, Z | 1 |
| Xie, X | 1 |
| Qiu, Y | 1 |
| Su, M | 1 |
| Jiang, T | 1 |
| Zhou, M | 1 |
| Zhao, A | 1 |
| Jia, W | 1 |
| Andersen, SL | 1 |
| Dumont, NL | 1 |
| Teicher, MH | 1 |
| van der Hart, MG | 1 |
| Czéh, B | 1 |
| de Biurrun, G | 1 |
| Michaelis, T | 1 |
| Watanabe, T | 1 |
| Natt, O | 1 |
| Frahm, J | 1 |
| Fuchs, E | 1 |
| Maciag, D | 1 |
| Simpson, KL | 1 |
| Coppinger, D | 1 |
| Lu, Y | 1 |
| Wang, Y | 1 |
| Lin, RC | 1 |
| Paul, IA | 1 |
| Calegari, L | 1 |
| Gorenstein, C | 1 |
| Gentil, V | 1 |
| Planeta, CS | 1 |
| Nunes-de-Souza, RL | 1 |
| Verberne, AJ | 1 |
| Taylor, DA | 1 |
| Fennessy, MR | 1 |
| Agras, WS | 1 |
| Kraemer, HC | 1 |
| File, SE | 1 |
| Tucker, JC | 1 |
| Lacey, JH | 2 |
| Crisp, AH | 2 |
| Pinder, RM | 1 |
| Blum, A | 1 |
| Stulemeijer, SM | 1 |
| Barres, M | 1 |
| Molczadzki, M | 1 |
| Rigaud, A | 1 |
| Charbaut, J | 1 |
| Israel, L | 1 |
| Kammerer, T | 1 |
| Mirmiran, M | 2 |
| van de Poll, NE | 2 |
| Corner, MA | 2 |
| van Oyen, HG | 2 |
| Bour, HL | 2 |
| Boer, GJ | 1 |
| Uylings, HB | 1 |
| Shioiri, T | 1 |
| Kato, T | 1 |
| Murashita, J | 1 |
| Yamada, N | 1 |
| Takahashi, S | 1 |
| Laguzzi, RF | 1 |
| Adrien, J | 1 |
| Bourgoin, S | 1 |
| Hamon, M | 1 |
| Broitman, ST | 1 |
| Donoso, AO | 1 |
| Broadhurst, AD | 1 |
| James, HD | 1 |
| Corte, LD | 1 |
| Heeley, AF | 1 |
| Groom, GV | 1 |
| Evans, G | 1 |
| Beaumont, G | 1 |
| O'Flanagan, PM | 1 |
| Marzouk, HF | 1 |
| Zuyderwijk, J | 1 |
| Uitterlinden, P | 1 |
| van Koetsveld, P | 1 |
| Blijd, JJ | 1 |
| Abou-Hashim, EM | 1 |
| el-Kannishy, MH | 1 |
| de Jong, FH | 1 |
| Lamberts, SW | 1 |
| Armario, A | 1 |
| García-Marquez, C | 1 |
| Giralt, M | 1 |
| Crutchfield, M | 1 |
4 trials available for clomipramine and Body Weight
| Article | Year |
|---|---|
The treatment of anorexia nervosa: do different treatments have different outcomes?
Topics: Adolescent; Amitriptyline; Anorexia Nervosa; Behavior Therapy; Body Weight; Clinical Trials as Topic | 1984 |
Hunger, food intake and weight: the impact of clomipramine on a refeeding anorexia nervosa population.
Topics: Anorexia Nervosa; Body Weight; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Eating; | 1980 |
A double-blind multicentre trial comparing the efficacy and side-effects of mianserin and chlorimipramine in depressed in- and outpatients.
Topics: Adolescent; Adult; Aged; Body Weight; Clinical Trials as Topic; Clomipramine; Depressive Disorder; D | 1980 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine | 1993 |
19 other studies available for clomipramine and Body Weight
| Article | Year |
|---|---|
The first observation of seasonal affective disorder symptoms in Rhesus macaque.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depression; Disease Models, An | 2015 |
Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Body | 2012 |
Differences in behavior and monoamine laterality following neonatal clomipramine treatment.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Behavior | 2002 |
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain Chemistry; Cell Division; Chronic Dise | 2002 |
Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry.
Topics: Animals; Animals, Newborn; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antigens, Nuclea | 2006 |
Effect of chronic treatment with clomipramine on food intake, macronutrient selection and body weight gain in rats.
Topics: Animals; Body Weight; Clomipramine; Diet; Dietary Carbohydrates; Eating; Food Preferences; Male; Pho | 2007 |
Withdrawal-like behaviour induced by inhibitors of biogenic amine reuptake in rats treated chronically with delta 9-tetrahydrocannabinol.
Topics: Animals; Biogenic Amines; Body Weight; Clomipramine; Dronabinol; Eating; Fluoxetine; Humans; Imipram | 1980 |
Prenatal treatment with clomipramine has an anxiolytic profile in the adolescent rat.
Topics: Age Factors; Aggression; Animals; Anxiety; Behavior, Animal; Body Weight; Clomipramine; Environment; | 1983 |
Suppression of active sleep by chronic treatment with chlorimipramine during early postnatal development: effects upon adult sleep and behavior in the rat.
Topics: Aggression; Aging; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Bra | 1981 |
Does rapid-eye-movement sleep play a role in brain development?
Topics: Animals; Behavior, Animal; Body Weight; Brain; Clomipramine; Female; Male; Organ Size; Rats; Sleep D | 1980 |
Effects of intraventricular injection of 6-hydroxydopamine in the developing kitten. 1. On the sleepwaking cycles.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Cats; Clomipramine; Do | 1979 |
Effects of chronic imipramine and clomipramine oral administration on maternal behavior and litter development.
Topics: Animals; Body Weight; Clomipramine; Dibenzazepines; Female; Growth; Imipramine; Maternal Behavior; M | 1978 |
Clomipramine plasma level and clinical response.
Topics: Administration, Oral; Adult; Aged; Body Weight; Clomipramine; Depression; Dibenzazepines; Female; Hu | 1977 |
The effect of long-term administration of toxic doses of clomipramine on plasma prolactin, luteinizing hormone, follicle stimulating hormone and testosterone in the male rat.
Topics: Animals; Body Weight; Clomipramine; Dibenzazepines; Follicle Stimulating Hormone; Luteinizing Hormon | 1977 |
An investigation into the short-term effects of clomipramine (Anafranil) administered in low doses, on weight.
Topics: Body Weight; Clomipramine; Dibenzazepines; Female; Humans; Male | 1977 |
Letter: A possible new treatment of weight loss in affective disorders and anorexia nervosa.
Topics: Adenosine Triphosphate; Affective Symptoms; Anorexia Nervosa; Body Weight; Clomipramine; Diazoxide; | 1976 |
Caffeine enhances the speed of the recovery of the hypothalamo-pituitary-adrenocortical axis after chronic prednisolone administration in the rat.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Body Weight; Caffeine; Clomipramine; Corticost | 1991 |
Previous chronic chlorimipramine treatment did not modify some physiological responses to acute and chronic stress in rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Clomipramine; Corticosterone; Eat | 1988 |
Clomipramine and 'drive' in people with anorexia nervosa: an in-patient study.
Topics: Adolescent; Adult; Anorexia Nervosa; Behavior; Body Weight; Clomipramine; Drive; Energy Intake; Fema | 1987 |