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clomipramine and Basal Ganglia Diseases

clomipramine has been researched along with Basal Ganglia Diseases in 5 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Clomipramine, haloperidol, and placebo were compared with baseline in the treatment of autism, and overall outcome, specific symptoms, and side effects were examined."9.09Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study. ( Gow, R; Konstantareas, M; Parker, K; Remington, G; Sloman, L, 2001)
"A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a."5.31Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. ( Dubisar, BM; Farrar, CD; Khan, R; Stoner, SC, 2002)
"Clomipramine, haloperidol, and placebo were compared with baseline in the treatment of autism, and overall outcome, specific symptoms, and side effects were examined."5.09Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study. ( Gow, R; Konstantareas, M; Parker, K; Remington, G; Sloman, L, 2001)
"The authors, by reference to a patient showing acathisia and other dyskinetic disorders following the administration to him of small doses of metoclopramide (Cerucal) and clomipramine, which is a thymoleptic, discuss extrapyramidal disorders attendant upon the therapy of larvated depressions or depressions accompanied by gastrointestinal disorders."3.65[Metoclopramide (Cerucal) side-effects in the form of extrapyramidal disorders in combination with an other antidepressive agent]. ( Felber, W; Ficker, F, 1977)
"7 mg/kg IM once), and for 3 days before hospitalization with clomipramine HCl at a prescribed dosage of 3."1.35Extrapyramidal side effects in a blue and gold macaw (Ara ararauna) treated with haloperidol and clomipramine. ( Albright, JD; Hickam, HD; Lynch, MJ; Morrisey, JK; Starkey, SR, 2008)
"A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a."1.31Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. ( Dubisar, BM; Farrar, CD; Khan, R; Stoner, SC, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Starkey, SR1
Morrisey, JK1
Hickam, HD1
Albright, JD1
Lynch, MJ1
Dubisar, BM1
Stoner, SC1
Khan, R1
Farrar, CD1
Escobar, R1
Bernardo, M1
Remington, G1
Sloman, L1
Konstantareas, M1
Parker, K1
Gow, R1
Ficker, F1
Felber, W1

Trials

1 trial available for clomipramine and Basal Ganglia Diseases

ArticleYear
Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Autistic Disorder; Basal

2001

Other Studies

4 other studies available for clomipramine and Basal Ganglia Diseases

ArticleYear
Extrapyramidal side effects in a blue and gold macaw (Ara ararauna) treated with haloperidol and clomipramine.
    Journal of avian medicine and surgery, 2008, Volume: 22, Issue:3

    Topics: Animals; Basal Ganglia Diseases; Bird Diseases; Clomipramine; Dopamine Antagonists; Female; Haloperi

2008
Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine.
    Pharmacotherapy, 2002, Volume: 22, Issue:11

    Topics: Adult; Asperger Syndrome; Basal Ganglia Diseases; Clomipramine; Humans; Interferon beta-1a; Interfer

2002
Schizophrenia, obsessive-compulsive disorder, and Tourette's syndrome: a case of triple comorbidity.
    The Journal of neuropsychiatry and clinical neurosciences, 1993,Winter, Volume: 5, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Brain; Clomipramine; Comorbidity; Female; Haloperidol; Humans; Obsess

1993
[Metoclopramide (Cerucal) side-effects in the form of extrapyramidal disorders in combination with an other antidepressive agent].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1977, Volume: 29, Issue:5

    Topics: Adult; Basal Ganglia Diseases; Clomipramine; Depression; Drug Combinations; Female; Gastrointestinal

1977