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clomipramine and Astrocytoma, Grade IV

clomipramine has been researched along with Astrocytoma, Grade IV in 1 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Research Excerpts

ExcerptRelevanceReference
"Glioblastoma is the most common and malignant primary brain tumour in adults, with a dismal prognosis."1.51Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma. ( Ashkan, K; Briscoe, AG; Burton, G; Hargreaves, IP; Heales, SJ; Holt, WV; Jung, J; Keatley, K; Littlewood, DTJ; McGeehan, JE; McGeehan, RE; Meunier, B; Pilkington, GJ; Rajala, N; Stromei-Cleroux, S; Wiltshire, T, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keatley, K1
Stromei-Cleroux, S1
Wiltshire, T1
Rajala, N1
Burton, G1
Holt, WV1
Littlewood, DTJ1
Briscoe, AG1
Jung, J1
Ashkan, K1
Heales, SJ1
Pilkington, GJ1
Meunier, B1
McGeehan, JE1
Hargreaves, IP1
McGeehan, RE1

Other Studies

1 other study available for clomipramine and Astrocytoma, Grade IV

ArticleYear
Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma.
    International journal of molecular sciences, 2019, Jul-09, Volume: 20, Issue:13

    Topics: Clomipramine; DNA, Mitochondrial; Germ-Line Mutation; Glioblastoma; Humans; Kaplan-Meier Estimate; M

2019