clomipramine has been researched along with Astrocytoma, Grade IV in 1 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Excerpt | Relevance | Reference |
---|---|---|
"Glioblastoma is the most common and malignant primary brain tumour in adults, with a dismal prognosis." | 1.51 | Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma. ( Ashkan, K; Briscoe, AG; Burton, G; Hargreaves, IP; Heales, SJ; Holt, WV; Jung, J; Keatley, K; Littlewood, DTJ; McGeehan, JE; McGeehan, RE; Meunier, B; Pilkington, GJ; Rajala, N; Stromei-Cleroux, S; Wiltshire, T, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Keatley, K | 1 |
Stromei-Cleroux, S | 1 |
Wiltshire, T | 1 |
Rajala, N | 1 |
Burton, G | 1 |
Holt, WV | 1 |
Littlewood, DTJ | 1 |
Briscoe, AG | 1 |
Jung, J | 1 |
Ashkan, K | 1 |
Heales, SJ | 1 |
Pilkington, GJ | 1 |
Meunier, B | 1 |
McGeehan, JE | 1 |
Hargreaves, IP | 1 |
McGeehan, RE | 1 |
1 other study available for clomipramine and Astrocytoma, Grade IV
Article | Year |
---|---|
Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma.
Topics: Clomipramine; DNA, Mitochondrial; Germ-Line Mutation; Glioblastoma; Humans; Kaplan-Meier Estimate; M | 2019 |