clomipramine has been researched along with Anxiety Disorders in 45 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Anxiety Disorders: Persistent and disabling ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to test the efficacy of clomipramine and fluoxetine, controlled by placebo, and compare their action in children and adolescents with anxiety disorders." | 9.17 | Comparison among clomipramine, fluoxetine, and placebo for the treatment of anxiety disorders in children and adolescents. ( Asbahr, FR; da Costa, CZ; de Morais, RM; Labbadia, EM; Lotufo Neto, F; Morikawa, M; Rodrigues, CL; Turkiewicz, G; Zanetta, DM, 2013) |
| "Seventeen outpatients with panic anxiety and agoraphobia were treated with a low, flexible dose of clomipramine in an 8-week open trial." | 9.06 | Panic attacks and agoraphobia: low dose clomipramine treatment. ( Codner, S; Cohen, L; Gladic, D; Gloger, S; Grunhaus, L; O'Ryan, F, 1989) |
| "A double-blind comparative study of clomipramine and fluvoxamine was performed in 50 patients suffering from anxiety disorders (DSM-III)." | 9.06 | Effect of serotonin uptake inhibitors in anxiety disorders; a double-blind comparison of clomipramine and fluvoxamine. ( den Boer, JA; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "A double-blind placebo-controlled study of 5-HTP and clomipramine was carried out on 45 patients suffering from anxiety disorders (DSM-III)." | 9.06 | Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. ( Gispen-de Wied, CC; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "A study was undertaken to assess the clinical response in cats diagnosed with anxiety-related or obsessive-compulsive disorders to a treatment regimen that included clomipramine and behaviour modification." | 7.70 | Use of clomipramine in the treatment of anxiety-related and obsessive-compulsive disorders in cats. ( Lindeman, MJ; Seksel, K, 1998) |
| "The purpose of this study was to test the efficacy of clomipramine and fluoxetine, controlled by placebo, and compare their action in children and adolescents with anxiety disorders." | 5.17 | Comparison among clomipramine, fluoxetine, and placebo for the treatment of anxiety disorders in children and adolescents. ( Asbahr, FR; da Costa, CZ; de Morais, RM; Labbadia, EM; Lotufo Neto, F; Morikawa, M; Rodrigues, CL; Turkiewicz, G; Zanetta, DM, 2013) |
| "Seventeen outpatients with panic anxiety and agoraphobia were treated with a low, flexible dose of clomipramine in an 8-week open trial." | 5.06 | Panic attacks and agoraphobia: low dose clomipramine treatment. ( Codner, S; Cohen, L; Gladic, D; Gloger, S; Grunhaus, L; O'Ryan, F, 1989) |
| "A double-blind comparative study of clomipramine and fluvoxamine was performed in 50 patients suffering from anxiety disorders (DSM-III)." | 5.06 | Effect of serotonin uptake inhibitors in anxiety disorders; a double-blind comparison of clomipramine and fluvoxamine. ( den Boer, JA; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "A double-blind placebo-controlled study of 5-HTP and clomipramine was carried out on 45 patients suffering from anxiety disorders (DSM-III)." | 5.06 | Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. ( Gispen-de Wied, CC; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "Clomipramine (25-150 mg/day) was given in a 2-month open clinical trial to patients with DSM-III defined panic disorder (N = 8) or agoraphobia with panic attacks (N = 12); 6 of these patients were found to have MVP." | 5.05 | Clomipramine treatment for panic attacks in patients with mitral valve prolapse. ( Birmacher, B; Gloger, S; Grunhaus, L, 1984) |
| "The largest body of work supporting the use of medications for childhood anxiety came from studies of obsessive-compulsive disorder, where clomipramine and fluoxetine have been found effective in systematic studies." | 4.79 | Current knowledge of medications for the treatment of childhood anxiety disorders. ( Allen, AJ; Leonard, H; Swedo, SE, 1995) |
| "Treatment with clomipramine, a tricyclic antidepressant, has proved useful for obsessional patients either as an adjunct to behavior therapy or as a primary treatment for patients who are not amenable to behavioral interventions." | 3.75 | Obsessive-compulsive disorder. ( Insel, TR, 1985) |
| "A study was undertaken to assess the clinical response in cats diagnosed with anxiety-related or obsessive-compulsive disorders to a treatment regimen that included clomipramine and behaviour modification." | 3.70 | Use of clomipramine in the treatment of anxiety-related and obsessive-compulsive disorders in cats. ( Lindeman, MJ; Seksel, K, 1998) |
| "Antidepressant therapy for panic attacks, exposure therapy for stimulus-dependent anxieties, and, to a lesser extent, clomipramine therapy for obsessive-compulsive symptoms have transformed the treatment of anxiety disorders and ushered in an era of rapid progress in research on anxiety and anxiety disorders." | 3.67 | New findings in anxiety. A synthesis for clinical practice in 1985. ( Curtis, GC, 1985) |
| "Clomipramine has been found superior to placebo or other psychoactive drugs in 5 controlled studies." | 2.37 | Antidepressant drugs in anxiety disorders. ( Modigh, K, 1987) |
| "Psychiatrists treated major depressive disorder in advanced cancer patients on the basis of the algorithm." | 1.35 | Clinical experience of the use of a pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer. ( Akechi, T; Akizuki, N; Ito, T; Nakano, T; Okamura, M; Shimizu, K; Uchitomi, Y, 2008) |
| "Patients with Tourette's syndrome often develop multiple psychopathological symptoms beyond the basic symptoms (motor and vocal tics)." | 1.31 | [Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear]. ( Barnett, W; Bednarz, K; Haisch, S, 2002) |
| "Lithium carbonate (600 mg/day) was then resumed." | 1.27 | [Rapid response of a disorder to the addition of lithium carbonate: panic resistant to tricyclic antidepressants]. ( Cournoyer, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (40.00) | 18.7374 |
| 1990's | 21 (46.67) | 18.2507 |
| 2000's | 5 (11.11) | 29.6817 |
| 2010's | 1 (2.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Costa, CZ | 1 |
| de Morais, RM | 1 |
| Zanetta, DM | 1 |
| Turkiewicz, G | 1 |
| Lotufo Neto, F | 1 |
| Morikawa, M | 1 |
| Rodrigues, CL | 1 |
| Labbadia, EM | 1 |
| Asbahr, FR | 1 |
| Bednarz, K | 1 |
| Haisch, S | 1 |
| Barnett, W | 1 |
| Okamura, M | 1 |
| Akizuki, N | 1 |
| Nakano, T | 1 |
| Shimizu, K | 1 |
| Ito, T | 1 |
| Akechi, T | 1 |
| Uchitomi, Y | 1 |
| Mavissakalian, M | 1 |
| Grunhaus, L | 3 |
| Gloger, S | 3 |
| Birmacher, B | 2 |
| Hertrich, O | 1 |
| Ananth, J | 1 |
| Pecknold, JC | 1 |
| van den Steen, N | 1 |
| Engelsmann, F | 1 |
| Troudart, T | 1 |
| Allen, AJ | 1 |
| Leonard, H | 1 |
| Swedo, SE | 1 |
| Wilens, TE | 1 |
| Spencer, T | 1 |
| Biederman, J | 1 |
| Wozniak, J | 1 |
| Connor, D | 1 |
| Jackson, CW | 1 |
| Morton, WA | 1 |
| Lydiard, RB | 2 |
| Balon, R | 1 |
| Yeragani, VK | 1 |
| Pohl, R | 1 |
| Ramesh, C | 1 |
| Phillips, KA | 1 |
| McElroy, SL | 1 |
| Keck, PE | 1 |
| Pope, HG | 1 |
| Hudson, JI | 1 |
| Ambrosini, PJ | 1 |
| Bianchi, MD | 1 |
| Rabinovich, H | 1 |
| Elia, J | 1 |
| Parker, G | 1 |
| Barrett, E | 1 |
| Ravindran, AV | 1 |
| Judge, R | 2 |
| Hunter, BN | 1 |
| Bray, J | 1 |
| Morton, NH | 1 |
| Seksel, K | 1 |
| Lindeman, MJ | 1 |
| Ninan, PT | 1 |
| Leroi, AM | 1 |
| Lalaude, O | 1 |
| Antonietti, M | 1 |
| Touchais, JY | 1 |
| Ducrotte, P | 1 |
| Menard, JF | 1 |
| Denis, P | 1 |
| Montgomery, SA | 1 |
| Matsunaga, H | 1 |
| Kiriike, N | 1 |
| Matsui, T | 1 |
| Iwasaki, Y | 1 |
| Stein, DJ | 1 |
| Escobar, JI | 1 |
| Gomez, O | 1 |
| Tuason, VB | 1 |
| Jalenques, I | 2 |
| Coudert, AJ | 2 |
| De la Fuente, JM | 1 |
| Mendlewicz, J | 1 |
| Wingerson, D | 1 |
| Nguyen, C | 1 |
| Roy-Byrne, PP | 1 |
| DeVeaugh-Geiss, J | 1 |
| Bihari, K | 1 |
| Pato, MT | 1 |
| Hill, JL | 1 |
| Murphy, DL | 1 |
| Greist, JH | 1 |
| Trimble, MR | 1 |
| Austin, LS | 1 |
| Fossey, MD | 1 |
| Zealberg, JJ | 1 |
| Laraia, MT | 1 |
| Ballenger, JC | 1 |
| Tiller, JW | 1 |
| Flament, MF | 1 |
| Koby, E | 1 |
| Rapoport, JL | 1 |
| Berg, CJ | 1 |
| Zahn, T | 1 |
| Cox, C | 1 |
| Denckla, M | 1 |
| Lenane, M | 1 |
| Fava, M | 1 |
| Anderson, K | 1 |
| Rosenbaum, JF | 1 |
| Jegede, RO | 1 |
| Baiyewu, O | 1 |
| Gladic, D | 1 |
| O'Ryan, F | 1 |
| Cohen, L | 1 |
| Codner, S | 1 |
| Curtis, GC | 1 |
| Liebowitz, MR | 1 |
| Fyer, AJ | 1 |
| Gorman, JM | 1 |
| Campeas, RB | 1 |
| Sandberg, DP | 1 |
| Hollander, E | 1 |
| Papp, LA | 1 |
| Klein, DF | 1 |
| Cournoyer, J | 1 |
| Westenberg, HG | 3 |
| den Boer, JA | 2 |
| Kahn, RS | 3 |
| Kamerbeek, WD | 2 |
| Verhoeven, WM | 2 |
| Feder, R | 1 |
| Gispen-de Wied, CC | 1 |
| Modigh, K | 1 |
| Insel, TR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Silymarin Treatment of Body Dysmorphic Disorder: A Double-Blind, Placebo-Controlled, Cross-Over Study[NCT02843451] | Phase 2 | 0 participants (Actual) | Interventional | 2016-10-31 | Withdrawn (stopped due to Focus on other studies) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for clomipramine and Anxiety Disorders
| Article | Year |
|---|---|
Pharmacologic treatment of anxiety disorders.
Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodia | 1982 |
Current knowledge of medications for the treatment of childhood anxiety disorders.
Topics: Adolescent; Age of Onset; Anti-Anxiety Agents; Anxiety Disorders; Child; Clomipramine; Fluoxetine; H | 1995 |
Antidepressant treatments in children and adolescents: II. Anxiety, physical, and behavioral disorders.
Topics: Adolescent; Antidepressive Agents; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; | 1993 |
Morbid jealousy as a variant of obsessive-compulsive disorder.
Topics: Anxiety Disorders; Clomipramine; Cognitive Behavioral Therapy; Combined Modality Therapy; Depressive | 1997 |
The functional anatomy, neurochemistry, and pharmacology of anxiety.
Topics: Adrenergic Uptake Inhibitors; Amygdala; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clomipram | 1999 |
[A limit of anxiety disorders. Obsessive-compulsive disorders in children and adolescents].
Topics: Adolescent; Anxiety Disorders; Child; Clomipramine; Family; Humans; Neuropsychology; Obsessive-Compu | 1992 |
Treating the anxiety: therapeutic options in obsessive compulsive disorder.
Topics: Anxiety Disorders; Behavior Therapy; Benzodiazepines; Clomipramine; Decision Trees; Humans; Neurotra | 1990 |
Worldwide use of clomipramine.
Topics: Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; | 1990 |
Tricyclic therapy of the DSM-III anxiety disorders: a review with implications for further research.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Anxiety Disorders; Child; Clomipramine; Humans; Obsess | 1988 |
Antidepressant drugs in anxiety disorders.
Topics: Antidepressive Agents; Anxiety Disorders; Clomipramine; Humans; Imipramine; Monoamine Oxidase Inhibi | 1987 |
Obsessive-compulsive disorder.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Clo | 1985 |
14 trials available for clomipramine and Anxiety Disorders
| Article | Year |
|---|---|
Comparison among clomipramine, fluoxetine, and placebo for the treatment of anxiety disorders in children and adolescents.
Topics: Adolescent; Anxiety Disorders; Child; Clomipramine; Double-Blind Method; Female; Fluoxetine; Humans; | 2013 |
Pharmacologic treatment of anxiety disorders.
Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodia | 1982 |
Clomipramine treatment for panic attacks in patients with mitral valve prolapse.
Topics: Age Factors; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Fear; Female; H | 1984 |
Double-blind comparative study of clomipramine and amitriptyline in obsessive neurosis.
Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder | 1981 |
A double-blind, multicenter study in primary care comparing paroxetine and clomipramine in patients with depression and associated anxiety. Paroxetine Study Group.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anxiety Disorders; Clomipramine; Comorbidity; Depress | 1997 |
Taijin kyofusho: a form of social anxiety disorder that responds to serotonin reuptake inhibitors?
Topics: Adolescent; Adult; Anxiety Disorders; Clomipramine; Culture; Female; Fluvoxamine; Humans; Japan; Mal | 2001 |
Clomipramine treatment for generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Clomipramine; Double-Blind Method; Female; Humans; Male; Psychiatric Statu | 1992 |
Worldwide use of clomipramine.
Topics: Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; | 1990 |
Antidepressants, alcohol and psychomotor performance.
Topics: Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder; Dose-Response Relations | 1990 |
Panic attacks and agoraphobia: low dose clomipramine treatment.
Topics: Adolescent; Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressiv | 1989 |
Psychopharmacology of anxiety disorders: on the role of serotonin in the treatment of anxiety states and phobic disorders.
Topics: 5-Hydroxytryptophan; Anxiety Disorders; Clomipramine; Female; Fluvoxamine; Humans; Male; Oximes; Ser | 1987 |
Effect of serotonin uptake inhibitors in anxiety disorders; a double-blind comparison of clomipramine and fluvoxamine.
Topics: Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Double-Blind Method; | 1987 |
Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
Topics: 5-Hydroxytryptophan; Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; | 1987 |
Obsessive-compulsive disorder.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Clo | 1985 |
23 other studies available for clomipramine and Anxiety Disorders
| Article | Year |
|---|---|
[Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear].
Topics: Adult; Anxiety Disorders; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Combined Modality | 2002 |
Clinical experience of the use of a pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer.
Topics: Adult; Aged; Algorithms; Alprazolam; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Benzod | 2008 |
[Ataractic treatment in psychiatry and general medicine. Overview of preparations, 3].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Chlorprothixene; Clobaza | 1983 |
Treatment of spontaneous panic attacks with chlomipramine.
Topics: Adult; Agoraphobia; Anxiety Disorders; Clomipramine; Female; Humans; Male; Middle Aged; Phobic Disor | 1981 |
Combined pharmacotherapy: an emerging trend in pediatric psychopharmacology.
Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Child Psychiatry; | 1995 |
Pharmacologic management of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depression; Dopamine; Fluox | 1994 |
Sexual dysfunction during antidepressant treatment.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder; | 1993 |
Body dysmorphic disorder: 30 cases of imagined ugliness.
Topics: Adolescent; Adult; Age Factors; Aged; Agoraphobia; Anxiety Disorders; Body Image; Clomipramine; Delu | 1993 |
Use of clomipramine in the treatment of anxiety-related and obsessive-compulsive disorders in cats.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior Therapy; Behavior, Animal; Ca | 1998 |
Prolonged stationary colonic motility recording in seven patients with severe constipation secondary to antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Cathartics; Cholinergic Antagonists; | 2000 |
Treatment of depression with associated anxiety: comparisons of tricyclic antidepressants and selective serotonin reuptake inhibitors.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Clomipramine; Depressive Disorder, Major; Fluox | 2000 |
Depressive subtypes, blood pressure changes and response to treatment.
Topics: Adult; Age Factors; Aged; Anxiety Disorders; Bipolar Disorder; Blood Pressure; Clomipramine; Depress | 1977 |
Carbamazepine addition in tricyclic antidepressant-resistant unipolar depression.
Topics: Aged; Anxiety Disorders; Carbamazepine; Clomipramine; Depressive Disorder; Dose-Response Relationshi | 1992 |
Academic medical center/industry collaboration.
Topics: Academic Medical Centers; Adolescent; Adult; Anxiety Disorders; Child; Clomipramine; Double-Blind Me | 1991 |
Neurologic soft signs in obsessive-compulsive disorder.
Topics: Adult; Anxiety Disorders; Central Nervous System Diseases; Clomipramine; Clonidine; Depressive Disor | 1991 |
Panic and phobic disorders in patients with obsessive compulsive disorder.
Topics: Acute Disease; Adolescent; Adult; Aged; Anxiety Disorders; Clomipramine; Comorbidity; Female; Humans | 1990 |
Childhood obsessive-compulsive disorder: a prospective follow-up study.
Topics: Adolescent; Adult; Anxiety Disorders; Child; Clomipramine; Depressive Disorder; Dexamethasone; Femal | 1990 |
"Anger attacks": possible variants of panic and major depressive disorders.
Topics: Adult; Anger; Anxiety Disorders; Clomipramine; Clonazepam; Depressive Disorder; Desipramine; Diagnos | 1990 |
A study of chronic neurotic illness in Nigeria.
Topics: Adult; Aged; Anxiety Disorders; Chronic Disease; Clomipramine; Drug Therapy, Combination; Female; Hu | 1989 |
[Is an obsessive-compulsive disorder in children an anxiety disorder?].
Topics: Adolescent; Anxiety Disorders; Child; Clomipramine; Compulsive Personality Disorder; Female; Humans; | 1989 |
New findings in anxiety. A synthesis for clinical practice in 1985.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Anxiety Disorders; Behavior Therapy; | 1985 |
[Rapid response of a disorder to the addition of lithium carbonate: panic resistant to tricyclic antidepressants].
Topics: Adult; Amitriptyline; Anxiety Disorders; Clomipramine; Depressive Disorder; Drug Therapy, Combinatio | 1986 |
Lithium augmentation of clomipramine.
Topics: Adult; Anxiety Disorders; Clomipramine; Depressive Disorder; Drug Synergism; Drug Therapy, Combinati | 1988 |