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clomipramine and Anxiety, Separation

clomipramine has been researched along with Anxiety, Separation in 15 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Anxiety, Separation: Anxiety experienced by an individual upon separation from a person or object of particular significance to the individual.

Research Excerpts

ExcerptRelevanceReference
"Clomipramine was effective and well-tolerated in controlling signs of obsessive-compulsive disorder and/or separation anxiety and/or noise phobia in 16 of 24 assessable cases, when used in combination with behaviour modification, and improvement in clinical signs was noted in 5 others."7.71Use of clomipramine in treatment of obsessive-compulsive disorder, separation anxiety and noise phobia in dogs: a preliminary, clinical study. ( Lindeman, MJ; Seksel, K, 2001)
"Clomipramine was effective and well-tolerated in controlling signs of obsessive-compulsive disorder and/or separation anxiety and/or noise phobia in 16 of 24 assessable cases, when used in combination with behaviour modification, and improvement in clinical signs was noted in 5 others."3.71Use of clomipramine in treatment of obsessive-compulsive disorder, separation anxiety and noise phobia in dogs: a preliminary, clinical study. ( Lindeman, MJ; Seksel, K, 2001)
"Clomipramine treatment had a sustained suppressive effect on the dogs' general activity levels, and a more modest suppressive effect on their attachment-related tendency to want much physical contact with their owners."2.69Evaluation of clomipramine as an adjunct to behavioural therapy in the treatment of separation-related problems in dogs. ( Hsu, Y; Podberscek, AL; Serpell, JA, 1999)
"Separation anxiety is a common behavioral problem in dogs."1.31Behavior modification and pharmacotherapy for separation anxiety in a 2-year-old pointer cross. ( Lem, M, 2002)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (26.67)18.2507
2000's8 (53.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Irimajiri, M2
Crowell-Davis, SL1
Fox, MW1
Kook, PH1
Kranjc, A1
Dennler, M1
Glaus, TM1
Gaultier, E1
Bonnafous, L1
Bougrat, L1
Lafont, C1
Pageat, P1
Frank, D1
Bert, B1
Harms, S1
Langen, B1
Fink, H1
Ghaffari, MS1
Khorami, N1
Marjani, M1
Aldavood, SJ1
Vila, G1
Mouren-Simeoni, MC1
Casey, RA1
Overall, KL1
Podberscek, AL1
Hsu, Y1
Serpell, JA1
Hewson, CJ1
Seksel, K1
Lindeman, MJ1
Lem, M1

Trials

2 trials available for clomipramine and Anxiety, Separation

ArticleYear
Comparison of the efficacy of a synthetic dog-appeasing pheromone with clomipramine for the treatment of separation-related disorders in dogs.
    The Veterinary record, 2005, Apr-23, Volume: 156, Issue:17

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior, Animal; Clomipramine; Dog

2005
Evaluation of clomipramine as an adjunct to behavioural therapy in the treatment of separation-related problems in dogs.
    The Veterinary record, 1999, Sep-25, Volume: 145, Issue:13

    Topics: Adult; Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior Therapy; Behavior, A

1999

Other Studies

13 other studies available for clomipramine and Anxiety, Separation

ArticleYear
Animal behavior case of the month. Separation anxiety.
    Journal of the American Veterinary Medical Association, 2014, Nov-01, Volume: 245, Issue:9

    Topics: Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Clomipramine; Clorazepate Dipot

2014
Questions ethics of crating.
    Journal of the American Veterinary Medical Association, 2015, Jan-01, Volume: 246, Issue:1

    Topics: Animals; Anxiety, Separation; Behavior, Animal; Clomipramine; Clorazepate Dipotassium; Dogs; Male

2015
The author responds.
    Journal of the American Veterinary Medical Association, 2015, Jan-01, Volume: 246, Issue:1

    Topics: Animals; Anxiety, Separation; Behavior, Animal; Clomipramine; Clorazepate Dipotassium; Dogs; Male

2015
Pancreatitis associated with clomipramine administration in a dog.
    The Journal of small animal practice, 2009, Volume: 50, Issue:2

    Topics: Animals; Anxiety, Separation; Clomipramine; Dog Diseases; Dogs; Male; Pancreatitis; Selective Seroto

2009
Animal behavior case of the month. Separation anxiety.
    Journal of the American Veterinary Medical Association, 2005, Sep-15, Volume: 227, Issue:6

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior Therapy; Behavior, Animal;

2005
Clomipramine and selegiline: do they influence impulse control?
    Journal of veterinary pharmacology and therapeutics, 2006, Volume: 29, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior, Animal; Clomipramine; Male

2006
Penile self-mutilation as an unusual sign of a separation-related problem in a crossbreed dog.
    The Journal of small animal practice, 2007, Volume: 48, Issue:11

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior, Animal; Clomipramine; Dogs

2007
[Panic attacks and panic disorders in the child].
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:1

    Topics: Anxiety, Separation; Child; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Dru

1993
Use of clomipramine for separation anxiety in dogs.
    The Veterinary record, 1998, May-23, Volume: 142, Issue:21

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior, Animal; Clomipramine; Dog

1998
Animal behavior case of the month. Stereotypical motor behavior that manifested when the owner departed or was out of the dog's sight.
    Journal of the American Veterinary Medical Association, 1998, Jul-01, Volume: 213, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior Therapy; Behavior, Animal;

1998
Clomipramine and behavioural therapy in the treatment of separation-related problems in dogs.
    The Veterinary record, 2000, Jan-22, Volume: 146, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior Therapy; Clomipramine; Dog

2000
Use of clomipramine in treatment of obsessive-compulsive disorder, separation anxiety and noise phobia in dogs: a preliminary, clinical study.
    Australian veterinary journal, 2001, Volume: 79, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior Therapy; Behavior, Animal;

2001
Behavior modification and pharmacotherapy for separation anxiety in a 2-year-old pointer cross.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2002, Volume: 43, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety, Separation; Behavior Therapy; Behavior, Animal;

2002