clomipramine has been researched along with Anhedonia in 1 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " After oral treatment with clomipramine (50 mg/kg/day) for four weeks, most of the depression-like behaviors were reversed, whereas the motivational reduction was not clearly affected." | 7.88 | Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews. ( Duan, Y; Li, M; Li, Y; Liang, J; Meng, X; Qi, K; Shen, F; Sui, N, 2018) |
| " After oral treatment with clomipramine (50 mg/kg/day) for four weeks, most of the depression-like behaviors were reversed, whereas the motivational reduction was not clearly affected." | 3.88 | Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews. ( Duan, Y; Li, M; Li, Y; Liang, J; Meng, X; Qi, K; Shen, F; Sui, N, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, F | 1 |
| Qi, K | 1 |
| Duan, Y | 1 |
| Li, Y | 1 |
| Liang, J | 1 |
| Meng, X | 1 |
| Li, M | 1 |
| Sui, N | 1 |
1 other study available for clomipramine and Anhedonia
| Article | Year |
|---|---|
Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews.
Topics: Anhedonia; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Di | 2018 |