clomipramine has been researched along with Anasarca in 5 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a previous controlled trial we have shown that premenstrual irritability and depressed mood (premenstrual syndrome) can be effectively reduced by low doses of the potent (but nonselective) serotonin reuptake inhibitor clomipramine taken each day of the menstrual cycle." | 9.07 | Clomipramine administered during the luteal phase reduces the symptoms of premenstrual syndrome: a placebo-controlled trial. ( Eriksson, E; Hedberg, MA; Sundblad, C, 1993) |
| "In a previous controlled trial we have shown that premenstrual irritability and depressed mood (premenstrual syndrome) can be effectively reduced by low doses of the potent (but nonselective) serotonin reuptake inhibitor clomipramine taken each day of the menstrual cycle." | 5.07 | Clomipramine administered during the luteal phase reduces the symptoms of premenstrual syndrome: a placebo-controlled trial. ( Eriksson, E; Hedberg, MA; Sundblad, C, 1993) |
| " In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis." | 3.80 | Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014) |
| "The effect of clomipramine (CMI), a tricyclic antidepressant, was studied on an acute inflammatory pain model in an attempt to understand its potential antinociceptive activity, the involvement of a central and/or peripheral component and its influence on the inflammatory process." | 3.68 | Evidence for a central but not a peripheral analgesic effect of clomipramine in rats. ( Ardid, D; Eschalier, A; Lavarenne, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, JJ | 1 |
| Xu, YQ | 1 |
| He, JH | 1 |
| Yu, HP | 1 |
| Huang, CJ | 1 |
| Gao, JM | 1 |
| Dong, QX | 1 |
| Xuan, YX | 1 |
| Li, CQ | 1 |
| Bianchi, M | 2 |
| Sacerdote, P | 2 |
| Panerai, AE | 2 |
| Sundblad, C | 1 |
| Hedberg, MA | 1 |
| Eriksson, E | 1 |
| Rossoni, G | 1 |
| Berti, F | 1 |
| Ardid, D | 1 |
| Eschalier, A | 1 |
| Lavarenne, J | 1 |
1 trial available for clomipramine and Anasarca
| Article | Year |
|---|---|
Clomipramine administered during the luteal phase reduces the symptoms of premenstrual syndrome: a placebo-controlled trial.
Topics: Adult; Affect; Appetite; Clomipramine; Dietary Carbohydrates; Edema; Female; Humans; Luteal Phase; N | 1993 |
4 other studies available for clomipramine and Anasarca
| Article | Year |
|---|---|
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease | 2014 |
Chlomipramine differently affects inflammatory edema and pain in the rat.
Topics: Adrenalectomy; Animals; Clomipramine; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Male; P | 1994 |
Effects of chlomipramine and fluoxetine on subcutaneous carrageenin-induced inflammation in the rat.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Carrageenan; Clomipramine; Dinoprostone; D | 1995 |
Evidence for a central but not a peripheral analgesic effect of clomipramine in rats.
Topics: Analgesics; Animals; Central Nervous System; Clomipramine; Edema; Foot; Injections; Injections, Intr | 1991 |