clomipramine has been researched along with Alloxan Diabetes in 7 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Corticosterone levels were increased in the untreated STZ group; SMV and clomipramine significantly decreased corticosterone levels in the STZ groups, but had no effect on the CTR groups." | 1.42 | Antidepressant-like effect of simvastatin in diabetic rats. ( ElBatsh, MM, 2015) |
| "Abolition of mechanical hyperalgesia was observed in mononeuropathic rats after five injections of clomipramine (5 mg·kg(-1) , s." | 1.37 | Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain? ( Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suehiro, K | 1 |
| Funao, T | 1 |
| Fujimoto, Y | 1 |
| Yamada, T | 1 |
| Mori, T | 1 |
| Nishikawa, K | 1 |
| ElBatsh, MM | 1 |
| Wattiez, AS | 1 |
| Libert, F | 1 |
| Privat, AM | 1 |
| Loiodice, S | 1 |
| Fialip, J | 2 |
| Eschalier, A | 2 |
| Courteix, C | 2 |
| Coudoré-Civiale, MA | 1 |
| Boucher, M | 1 |
| Méen, M | 1 |
| Ardid, D | 1 |
| Massol, J | 3 |
| Martin, P | 3 |
| Chatelain, F | 2 |
| Puech, AJ | 3 |
| Belon, JP | 1 |
| Soubrié, P | 2 |
7 other studies available for clomipramine and Alloxan Diabetes
| Article | Year |
|---|---|
Relationship between noradrenaline release in the locus coeruleus and antiallodynic efficacy of analgesics in rats with painful diabetic neuropathy.
Topics: Adrenergic Neurons; Analgesics; Animals; Clomipramine; Diabetes Mellitus, Experimental; Diabetic Neu | 2013 |
Antidepressant-like effect of simvastatin in diabetic rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Corticosterone; Depression; Diabetes | 2015 |
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experime | 2011 |
Potentiation of morphine and clomipramine analgesia by cholecystokinin -B antagonist CI-988 in diabetic rats.
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomi | 2000 |
Tricyclic antidepressants, thyroid function, and their relationship with the behavioral responses in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arousal; Avoidance Learning; Clomipramine; Conditioning, | 1990 |
Helpless behavior (escape deficits) in streptozotocin-diabetic rats: resistance to antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brain; Clenbuterol; Clomipramine; Conditioning, Operant; Desipramine | 1989 |
Impaired response of experimental diabetic mice to tricyclics: a possible beta-adrenergic mechanism.
Topics: Animals; Clenbuterol; Clomipramine; Desipramine; Diabetes Mellitus, Experimental; Dose-Response Rela | 1988 |