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clomipramine and Alcoholism

clomipramine has been researched along with Alcoholism in 8 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research Excerpts

ExcerptRelevanceReference
"2mg/ml); ethyl glucuronide as a marker of chronic alcohol abuse was detected in the deceased's hair (0."3.73A fatal clomipramine intoxication case of a chronic alcoholic patient: application of postmortem hair analysis method of clomipramine and ethyl glucuronide using LC/APCI/MS. ( Kołodziej, J; Kłys, M; Rojek, S; Scisłowski, M, 2005)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kłys, M1
Scisłowski, M1
Rojek, S1
Kołodziej, J1
Borg, V1
George, DT1
Nutt, DJ1
Rawlings, RR1
Phillips, MJ1
Eckardt, MJ1
Potter, WZ1
Linnoila, M1
Rowe, JB1
Sullivan, PF1
Mulder, RT1
Joyce, PR1
Colgan, A1
Wootton, LW1
Bailey, RI1
Balant-Gorgia, AE1
Gay, M1
Gex-Fabry, M1
Balant, LP1
Fraser, AD1
Isner, AF1
Moss, MA1

Trials

3 trials available for clomipramine and Alcoholism

ArticleYear
[Clinical trial of Tegretol and Anafranil/Sinequan in alcohol abstinence symptoms].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Feb-20, Volume: 100, Issue:5

    Topics: Alcoholism; Carbamazepine; Clinical Trials as Topic; Clomipramine; Depression; Double-Blind Method;

1980
Behavioral and endocrine responses to clomipramine in panic disorder patients with or without alcoholism.
    Biological psychiatry, 1995, Jan-15, Volume: 37, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Arousal; Brain; Clomipramine; Female; Humans; Hydroc

1995
The effect of a history of conduct disorder in adult major depression.
    Journal of affective disorders, 1996, Feb-12, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Tricyclic; Child; Child Behavior Disorders; Cl

1996

Other Studies

5 other studies available for clomipramine and Alcoholism

ArticleYear
A fatal clomipramine intoxication case of a chronic alcoholic patient: application of postmortem hair analysis method of clomipramine and ethyl glucuronide using LC/APCI/MS.
    Legal medicine (Tokyo, Japan), 2005, Volume: 7, Issue:5

    Topics: Adult; Alcoholism; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Clomipramine; Drug Inte

2005
A pilot study of anafranil in the treatment of phobic states.
    Scottish medical journal, 1975, Volume: 20, Issue:1 SUPPL

    Topics: Administration, Oral; Adult; Alcoholism; Blood Pressure; Clomipramine; Depression; Dibenzazepines; D

1975
A preliminary report on the use of clomipramine in general practice.
    Scottish medical journal, 1975, Volume: 20, Issue:1 SUPPL

    Topics: Administration, Oral; Adult; Aged; Alcoholism; Clomipramine; Depression; Dibenzazepines; Family Prac

1975
Persistent impairment of clomipramine demethylation in recently detoxified alcoholic patients.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:2

    Topics: Adult; Alcoholism; Clomipramine; Dealkylation; Desipramine; Female; Humans; Hydroxylation; Imipramin

1992
A fatality involving clomipramine.
    Journal of forensic sciences, 1986, Volume: 31, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Chromatography, High

1986