clomipramine has been researched along with Agranulocytosis in 6 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 67-year-old man developed concurrent severe agranulocytosis and elevation of hepatic transaminases as a result of treatment with clomipramine." | 7.68 | Concurrent agranulocytosis and hepatitis secondary to clomipramine therapy. ( Alderman, CP; Atchison, MM; McNeece, JI, 1993) |
| "A 67-year-old man developed concurrent severe agranulocytosis and elevation of hepatic transaminases as a result of treatment with clomipramine." | 3.68 | Concurrent agranulocytosis and hepatitis secondary to clomipramine therapy. ( Alderman, CP; Atchison, MM; McNeece, JI, 1993) |
| " We report the isolation of Rothia dentocariosa from the blood of a septicaemic patient with chronic lymphocytic leukaemia and bone marrow depression following treatment with clomipramine and zuclopentixol." | 3.67 | Rothia dentocariosa septicaemia in a patient with chronic lymphocytic leukaemia and toxic granulocytopenia. ( Hansen, NE; Jønsson, V; Kristiansen, JE; Pers, C, 1987) |
| " We report a case of agranulocytosis due to clomipramine, and discuss principles of management." | 3.67 | Tricyclic antidepressant agranulocytosis. ( Blake, G; Gravenor, DS; Leclerc, JR, 1986) |
| "Two cases of agranulocytosis occurring after addition of a butyrophenone to a course of phenothiazine treatment are reported and possible mechanisms for this interaction are discussed." | 1.28 | Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment. ( Kehoe, R; Young, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hunt, KA | 1 |
| Resnick, MP | 1 |
| Alderman, CP | 1 |
| Atchison, MM | 1 |
| McNeece, JI | 1 |
| Souhami, RL | 1 |
| Ashton, CR | 1 |
| Lee-Potter, JP | 1 |
| Young, A | 1 |
| Kehoe, R | 1 |
| Pers, C | 1 |
| Kristiansen, JE | 1 |
| Jønsson, V | 1 |
| Hansen, NE | 1 |
| Gravenor, DS | 1 |
| Leclerc, JR | 1 |
| Blake, G | 1 |
6 other studies available for clomipramine and Agranulocytosis
| Article | Year |
|---|---|
Clomipramine-induced agranulocytosis and its treatment with G-CSF.
Topics: Adult; Agranulocytosis; Clomipramine; Female; Granulocyte Colony-Stimulating Factor; Humans | 1993 |
Concurrent agranulocytosis and hepatitis secondary to clomipramine therapy.
Topics: Aged; Agranulocytosis; Chemical and Drug Induced Liver Injury; Clomipramine; Depressive Disorder; Hu | 1993 |
Agranulocytosis and systemic candidiasis following clomipramine therapy.
Topics: Adult; Agranulocytosis; Candidiasis; Clomipramine; Depression; Dibenzazepines; Female; Flucytosine; | 1976 |
Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment.
Topics: Agranulocytosis; Antipsychotic Agents; Chlorpromazine; Clomipramine; Depressive Disorder; Dose-Respo | 1989 |
Rothia dentocariosa septicaemia in a patient with chronic lymphocytic leukaemia and toxic granulocytopenia.
Topics: Actinomycetaceae; Actinomycetales Infections; Aged; Agranulocytosis; Clomipramine; Clopenthixol; Dep | 1987 |
Tricyclic antidepressant agranulocytosis.
Topics: Agranulocytosis; Clomipramine; Female; Humans; Middle Aged | 1986 |