clomipramine has been researched along with Affective Disorders, Psychotic in 6 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Affective Disorders, Psychotic: Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Out of ten consecutive patients with DSM-III-R obsessive-compulsive disorder without any previous history of bipolarity, three patients showed antidepressant-induced hypomania (clomipramine, one patient; fluvoxamine, two patients) within the first 5 to 8 weeks of the drug treatment." | 3.69 | Antidepressant-induced hypomania in obsessive-compulsive disorder. ( Barsi, J; Belsõ, N; György, S; Pestality, P; Rihmer, Z, 1996) |
| " No correlation between pharmacokinetic and improvement parameters could be found." | 1.27 | Nonlinear pharmacokinetics of chlorimipramine after infusion and oral administration in patients. ( Jungkunz, G; Kuss, HJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavaliere, F | 1 |
| Fornarelli, A | 1 |
| Bertan, F | 1 |
| Russo, R | 1 |
| Marsal-Cots, A | 1 |
| Morrone, LA | 1 |
| Adornetto, A | 1 |
| Corasaniti, MT | 1 |
| Bano, D | 1 |
| Bagetta, G | 1 |
| Nicotera, P | 1 |
| Simon, P | 1 |
| Lecrubier, Y | 1 |
| Jouvent, R | 1 |
| Puech, A | 1 |
| Widlocher, D | 1 |
| Noguchi, T | 1 |
| Rihmer, Z | 1 |
| Barsi, J | 1 |
| Belsõ, N | 1 |
| Pestality, P | 1 |
| György, S | 1 |
| Yamawaki, S | 1 |
| Kagaya, A | 1 |
| Tawara, Y | 1 |
| Inagaki, M | 1 |
| Kuss, HJ | 1 |
| Jungkunz, G | 1 |
1 review available for clomipramine and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Intracellular calcium signaling systems in the pathophysiology of affective disorders.
Topics: Affective Disorders, Psychotic; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Ca | 1998 |
1 trial available for clomipramine and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Beta-receptor stimulation in the treatment of depression.
Topics: Affective Disorders, Psychotic; Albuterol; Bipolar Disorder; Clinical Trials as Topic; Clomipramine; | 1984 |
4 other studies available for clomipramine and Affective Disorders, Psychotic
| Article | Year |
|---|---|
The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux.
Topics: Affective Disorders, Psychotic; Animals; Antidepressive Agents, Tricyclic; Autophagy; Caenorhabditis | 2019 |
[Clinical significance of plasma levels of clomipramine and its desmethylated and hydroxylated metabolites].
Topics: Administration, Oral; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clomipramine; Female; | 1993 |
Antidepressant-induced hypomania in obsessive-compulsive disorder.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Antidepressive Agents; Clomipramine; Female; Fluv | 1996 |
Nonlinear pharmacokinetics of chlorimipramine after infusion and oral administration in patients.
Topics: Administration, Oral; Affective Disorders, Psychotic; Clomipramine; Female; Humans; Infusions, Intra | 1986 |