clomipramine has been researched along with Adjustment Disorders in 13 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Adjustment Disorders: Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double blind control comparison on the effects of 50 mg of clomipramine given three times a day and 150 mg of clomipramine in a single bedtime dosage revealed no significant differences in therapeutic efficacy." | 2.64 | Are divided doses of tricyclic antidepressants necessary? ( Miller, SI; Schubert, DS, 1978) |
| "In respect of the number of patients : bipolar depressions (10 cases) unipolar (20 cases) it has not been possible to study the results in these 2 sub groups." | 2.64 | [The clomipramine-lithium combination: controlled trial]. ( Des Lauriers, A; Luaute, JP; Moinet, A; Monfort, J; Nick, J, 1976) |
| "Depression was by far the most important factor." | 1.26 | Cortisol in the CSF of depressed and suicidal patients. ( Asberg, M; Bertilsson, L; Lantto, O; Schalling, D; Träskman, L; Tybring, G, 1980) |
| "Clomipramine is a tricyclic antidepressant widely used." | 1.26 | [Clomipramine and desmethylclomipramine: relationship between plasma levels and clinical effect (author's transl)]. ( Allers, G; Jounet, JM; Vandel, B; Vandel, S; Volmat, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Träskman, L | 1 |
| Tybring, G | 1 |
| Asberg, M | 1 |
| Bertilsson, L | 1 |
| Lantto, O | 1 |
| Schalling, D | 1 |
| Stewart, JW | 1 |
| Quitkin, F | 1 |
| Fyer, A | 1 |
| Rifkin, A | 1 |
| McGrath, P | 1 |
| Liebowitz, M | 1 |
| Rosnick, L | 1 |
| Klein, DF | 1 |
| Vandel, B | 1 |
| Vandel, S | 1 |
| Jounet, JM | 1 |
| Allers, G | 1 |
| Volmat, R | 1 |
| Ehsanullah, RS | 1 |
| Ravizza, L | 1 |
| Mulgirigama, LD | 1 |
| Pare, CM | 1 |
| Turner, P | 1 |
| Wadsworth, J | 1 |
| Witts, DJ | 1 |
| Schubert, DS | 2 |
| Miller, SI | 1 |
| Kielholz, P | 1 |
| Adams, C | 1 |
| Nick, J | 1 |
| Luaute, JP | 1 |
| Des Lauriers, A | 1 |
| Moinet, A | 1 |
| Monfort, J | 1 |
| Planche, R | 1 |
| Gathier, MC | 1 |
| Lambert, J | 1 |
| Bercegeay, R | 1 |
| Le Roux, JL | 1 |
| Larsen, JK | 1 |
| Holm, P | 1 |
| Høyer, E | 1 |
| Mejlhede, A | 1 |
| Mikkelsen, PL | 1 |
| Olesen, A | 1 |
| Schaumburg, E | 1 |
5 trials available for clomipramine and Adjustment Disorders
| Article | Year |
|---|---|
Efficacy of desipramine in endogenomorphically depressed patients.
Topics: Adjustment Disorders; Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder | 1980 |
Clinical responses in depressed patients in relation to plasma levels of tricyclic antidepressants and tyramine pressor response.
Topics: Adjustment Disorders; Adult; Aged; Anthracenes; Clinical Trials as Topic; Clomipramine; Depression; | 1977 |
Are divided doses of tricyclic antidepressants necessary?
Topics: Adjustment Disorders; Adult; Clinical Trials as Topic; Clomipramine; Dibenzazepines; Double-Blind Me | 1978 |
[The clomipramine-lithium combination: controlled trial].
Topics: Adjustment Disorders; Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Clomipramine; Depress | 1976 |
Moclobemide and clomipramine in reactive depression. A placebo-controlled randomized clinical trial.
Topics: Adjustment Disorders; Adult; Aged; Antidepressive Agents; Benzamides; Clinical Trials as Topic; Clom | 1989 |
8 other studies available for clomipramine and Adjustment Disorders
| Article | Year |
|---|---|
Cortisol in the CSF of depressed and suicidal patients.
Topics: Adjustment Disorders; Clomipramine; Depression; Female; Homovanillic Acid; Humans; Hydrocortisone; H | 1980 |
[Clomipramine and desmethylclomipramine: relationship between plasma levels and clinical effect (author's transl)].
Topics: Adjustment Disorders; Adult; Aged; Clomipramine; Depressive Disorder; Female; Humans; Kinetics; Male | 1981 |
Uptake of 5-hydroxytryptamine and dopamine into platelets from depressed patients and normal subjects--influence of clomipramine, desmethylclomipramine and maprotiline.
Topics: Adjustment Disorders; Adult; Aged; Antidepressive Agents, Tricyclic; Blood Platelets; Clomipramine; | 1980 |
[Clinical and biochemical contributions on the effect of maprotiline and clomipramine in depressive states (preliminary observation)].
Topics: Adjustment Disorders; Adult; Anthracenes; Blood Platelets; Clomipramine; Depression; Female; Humans; | 1979 |
A biphasic change in mood with a tricyclic antidepressant.
Topics: Adjustment Disorders; Anxiety; Clomipramine; Dibenzazepines; Emotions; Humans | 1979 |
[Diagnosis and treatment of depressive states in everyday practice (author's transl)].
Topics: Adjustment Disorders; Antidepressive Agents; Bipolar Disorder; Clomipramine; Family Practice; Fatigu | 1978 |
[Description of a simple graphic model permitting the comparison of the course of depressive states].
Topics: Adjustment Disorders; Adult; Antidepressive Agents; Anxiety; Clomipramine; Depression; Doxepin; Fema | 1976 |
[Value of combination of sulpiride and clomiprmaine in certain depressive states (apropos of 2 cases].
Topics: Adjustment Disorders; Clomipramine; Dibenzazepines; Drug Combinations; Drug Evaluation; Female; Huma | 1975 |