clomipramine has been researched along with Acute Confusional Senile Dementia in 5 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clomipramine appeared much more effective and better tolerated than fluoxetine in this very old patient despite its potential anticholinergic effect and the coexistence of Alzheimer disease." | 7.70 | Treatment of obsessive-compulsive disorder using clomipramine in a very old patient. ( Trappler, B, 1999) |
| "In patients with Down's syndrome or Alzheimer's disease, beta-endorphin concentrations in peripheral blood mononuclear cells behave similarly to those in age-matched normal subjects." | 5.28 | Beta-endorphin concentrations in resting peripheral mononuclear cells and after treatment with PHA or serotoninergic drugs in human aging, Alzheimer's disease, and Down's syndrome. ( Manfredi, B; Panerai, AE; Sacerdote, P, 1992) |
| "Clomipramine appeared much more effective and better tolerated than fluoxetine in this very old patient despite its potential anticholinergic effect and the coexistence of Alzheimer disease." | 3.70 | Treatment of obsessive-compulsive disorder using clomipramine in a very old patient. ( Trappler, B, 1999) |
| "Clomipramine proved to be a useful treatment of depression in patients with probable AD." | 2.68 | A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease. ( Chemerinski, E; Leiguarda, R; Petracca, G; Starkstein, SE; Tesón, A, 1996) |
| "In patients with Down's syndrome or Alzheimer's disease, beta-endorphin concentrations in peripheral blood mononuclear cells behave similarly to those in age-matched normal subjects." | 1.28 | Beta-endorphin concentrations in resting peripheral mononuclear cells and after treatment with PHA or serotoninergic drugs in human aging, Alzheimer's disease, and Down's syndrome. ( Manfredi, B; Panerai, AE; Sacerdote, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajjo, R | 1 |
| Setola, V | 1 |
| Roth, BL | 1 |
| Tropsha, A | 1 |
| Petracca, G | 1 |
| Tesón, A | 1 |
| Chemerinski, E | 1 |
| Leiguarda, R | 1 |
| Starkstein, SE | 1 |
| Trappler, B | 1 |
| Panerai, AE | 1 |
| Manfredi, B | 1 |
| Sacerdote, P | 1 |
| Ostergaard, PK | 1 |
1 trial available for clomipramine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Antidepressive Agents, Tricyclic; Clomipramine; | 1996 |
4 other studies available for clomipramine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.
Topics: Alzheimer Disease; Cell Line, Tumor; Cloning, Molecular; Cognition; Drug Discovery; Drug Evaluation, | 2012 |
Treatment of obsessive-compulsive disorder using clomipramine in a very old patient.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; B | 1999 |
Beta-endorphin concentrations in resting peripheral mononuclear cells and after treatment with PHA or serotoninergic drugs in human aging, Alzheimer's disease, and Down's syndrome.
Topics: Adult; Aged; Aging; Alzheimer Disease; beta-Endorphin; Clomipramine; Down Syndrome; Female; Humans; | 1992 |
Capgras syndrome in senile dementia of the Alzheimer type.
Topics: Aged; Alzheimer Disease; Capgras Syndrome; Clomipramine; Female; Haloperidol; Humans; Psychotic Diso | 1985 |