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clofilium and Tachycardia

clofilium has been researched along with Tachycardia in 4 studies

clofilium: RN given refers to parent cpd; structure

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
" Propranolol, dl-sotalol, azimilide, and d-sotalol inhibited isoproterenol-induced tachycardia with IC50 values (the concentration giving 50% inhibition of isoproterenol-stimulated heart rate) of 0."7.70Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart. ( Brooks, RR; Carpenter, JF; Miller, KE, 1998)
" Propranolol, dl-sotalol, azimilide, and d-sotalol inhibited isoproterenol-induced tachycardia with IC50 values (the concentration giving 50% inhibition of isoproterenol-stimulated heart rate) of 0."3.70Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart. ( Brooks, RR; Carpenter, JF; Miller, KE, 1998)
"When low doses of clofilium were administered to conscious rabbits, ventricular tachyarrhythmia (VT) with features typical of torsades de pointes developed."3.68QTU-prolongation and torsades de pointes induced by putative class III antiarrhythmic agents in the rabbit: etiology and interventions. ( Almgren, O; Carlsson, L; Duker, G, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lis, R1
Davey, DD1
Morgan, TK1
Lumma, WC1
Wohl, RA1
Jain, VK1
Wan, CN1
Argentieri, TM1
Sullivan, ME1
Cantor, EH1
Rinkenberger, RL1
Prystowsky, EN1
Jackman, WM1
Naccarelli, GV1
Heger, JJ1
Zipes, DP1
Miller, KE1
Carpenter, JF1
Brooks, RR1
Carlsson, L1
Almgren, O1
Duker, G1

Other Studies

4 other studies available for clofilium and Tachycardia

ArticleYear
Synthesis and antiarrhythmic activity of novel 3-alkyl-1-[omega-[4-[(alkylsulfonyl)amino]phenyl]-omega- hydroxyalkyl]-1H-imidazolium salts and related compounds. 2.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:12

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Imidazoles; In Vitro Techniques; Purkinje

1987
Drug conversion of nonsustained ventricular tachycardia to sustained ventricular tachycardia during serial electrophysiologic studies: identification of drugs that exacerbate tachycardia and potential mechanisms.
    American heart journal, 1982, Volume: 103, Issue:2

    Topics: Adult; Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Cardiac Catheterization; Disop

1982
Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Electrocardiography; Guinea Pigs; Heart;

1998
QTU-prolongation and torsades de pointes induced by putative class III antiarrhythmic agents in the rabbit: etiology and interventions.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Chloralose; Disea

1990