clofilium has been researched along with Tachycardia in 4 studies
clofilium: RN given refers to parent cpd; structure
Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Propranolol, dl-sotalol, azimilide, and d-sotalol inhibited isoproterenol-induced tachycardia with IC50 values (the concentration giving 50% inhibition of isoproterenol-stimulated heart rate) of 0." | 7.70 | Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart. ( Brooks, RR; Carpenter, JF; Miller, KE, 1998) |
| " Propranolol, dl-sotalol, azimilide, and d-sotalol inhibited isoproterenol-induced tachycardia with IC50 values (the concentration giving 50% inhibition of isoproterenol-stimulated heart rate) of 0." | 3.70 | Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart. ( Brooks, RR; Carpenter, JF; Miller, KE, 1998) |
| "When low doses of clofilium were administered to conscious rabbits, ventricular tachyarrhythmia (VT) with features typical of torsades de pointes developed." | 3.68 | QTU-prolongation and torsades de pointes induced by putative class III antiarrhythmic agents in the rabbit: etiology and interventions. ( Almgren, O; Carlsson, L; Duker, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lis, R | 1 |
| Davey, DD | 1 |
| Morgan, TK | 1 |
| Lumma, WC | 1 |
| Wohl, RA | 1 |
| Jain, VK | 1 |
| Wan, CN | 1 |
| Argentieri, TM | 1 |
| Sullivan, ME | 1 |
| Cantor, EH | 1 |
| Rinkenberger, RL | 1 |
| Prystowsky, EN | 1 |
| Jackman, WM | 1 |
| Naccarelli, GV | 1 |
| Heger, JJ | 1 |
| Zipes, DP | 1 |
| Miller, KE | 1 |
| Carpenter, JF | 1 |
| Brooks, RR | 1 |
| Carlsson, L | 1 |
| Almgren, O | 1 |
| Duker, G | 1 |
4 other studies available for clofilium and Tachycardia
| Article | Year |
|---|---|
Synthesis and antiarrhythmic activity of novel 3-alkyl-1-[omega-[4-[(alkylsulfonyl)amino]phenyl]-omega- hydroxyalkyl]-1H-imidazolium salts and related compounds. 2.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Imidazoles; In Vitro Techniques; Purkinje | 1987 |
Drug conversion of nonsustained ventricular tachycardia to sustained ventricular tachycardia during serial electrophysiologic studies: identification of drugs that exacerbate tachycardia and potential mechanisms.
Topics: Adult; Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Cardiac Catheterization; Disop | 1982 |
Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Electrocardiography; Guinea Pigs; Heart; | 1998 |
QTU-prolongation and torsades de pointes induced by putative class III antiarrhythmic agents in the rabbit: etiology and interventions.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Chloralose; Disea | 1990 |