clofilium has been researched along with Mitochondrial Diseases in 2 studies
clofilium: RN given refers to parent cpd; structure
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mutations in POLG are a major cause of mitochondrial disorders including hepatic insufficiency, Alpers syndrome, progressive external ophthalmoplegia, sensory neuropathy and ataxia." | 1.43 | Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases. ( Baruffini, E; Delahodde, A; Lodi, T; Pitayu, L; Rodier, C; Rötig, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Facchinello, N | 1 |
| Laquatra, C | 1 |
| Locatello, L | 1 |
| Beffagna, G | 1 |
| Brañas Casas, R | 1 |
| Fornetto, C | 1 |
| Dinarello, A | 1 |
| Martorano, L | 1 |
| Vettori, A | 1 |
| Risato, G | 1 |
| Celeghin, R | 1 |
| Meneghetti, G | 1 |
| Santoro, MM | 1 |
| Delahodde, A | 2 |
| Vanzi, F | 1 |
| Rasola, A | 1 |
| Dalla Valle, L | 1 |
| Rasotto, MB | 1 |
| Lodi, T | 2 |
| Baruffini, E | 2 |
| Argenton, F | 1 |
| Tiso, N | 1 |
| Pitayu, L | 1 |
| Rodier, C | 1 |
| Rötig, A | 1 |
2 other studies available for clofilium and Mitochondrial Diseases
| Article | Year |
|---|---|
Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish.
Topics: Animals; Disease Models, Animal; Mitochondrial Diseases; Phenotype; Quaternary Ammonium Compounds; Z | 2021 |
Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases.
Topics: Animals; Caenorhabditis elegans; DNA Polymerase gamma; DNA Polymerase I; DNA Replication; DNA-Direct | 2016 |