clofilium has been researched along with Long QT Syndrome in 5 studies
clofilium: RN given refers to parent cpd; structure
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Data analysis was performed on premature ventricular complexes, couplets, and torsades de pointes (TdP) induced during intravenous administration of clofilium and phenylephrine with combinations of various infusion rates." | 1.39 | Noninvasive cardiac activation imaging of ventricular arrhythmias during drug-induced QT prolongation in the rabbit heart. ( Han, C; He, B; Killingsworth, CR; Pogwizd, SM; Zhou, Z, 2013) |
| "The ventricular arrhythmia torsade de pointes (TdP) occurs after QT interval prolongation and is associated with sudden cardiac death." | 1.30 | Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits. ( Anderson, ME; Mazur, A; Roden, DM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, C | 1 |
| Pogwizd, SM | 1 |
| Killingsworth, CR | 1 |
| Zhou, Z | 1 |
| He, B | 1 |
| Belardinelli, L | 1 |
| Liu, G | 1 |
| Smith-Maxwell, C | 1 |
| Wang, WQ | 1 |
| El-Bizri, N | 1 |
| Hirakawa, R | 1 |
| Karpinski, S | 1 |
| Li, CH | 1 |
| Hu, L | 1 |
| Li, XJ | 1 |
| Crumb, W | 1 |
| Wu, L | 1 |
| Koltun, D | 1 |
| Zablocki, J | 1 |
| Yao, L | 1 |
| Dhalla, AK | 1 |
| Rajamani, S | 1 |
| Shryock, JC | 1 |
| Hasumi, H | 1 |
| Matsuda, R | 1 |
| Shimamoto, K | 1 |
| Hata, Y | 1 |
| Kaneko, N | 1 |
| Mazur, A | 1 |
| Roden, DM | 1 |
| Anderson, ME | 1 |
| Carlsson, L | 1 |
| Abrahamsson, C | 1 |
| Drews, L | 1 |
| Duker, G | 1 |
5 other studies available for clofilium and Long QT Syndrome
| Article | Year |
|---|---|
Noninvasive cardiac activation imaging of ventricular arrhythmias during drug-induced QT prolongation in the rabbit heart.
Topics: Animals; Anti-Arrhythmia Agents; Body Surface Potential Mapping; Cardiotonic Agents; Disease Models, | 2013 |
A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias.
Topics: Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic | 2013 |
K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Bl | 2007 |
Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Antiarrhythmic effects of potassium channel openers in rhythm abnormalities related to delayed repolarization.
Topics: Animals; Anti-Arrhythmia Agents; Electrocardiography; Glyburide; Guanidines; Heart Conduction System | 1992 |