clofilium has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 2 studies
clofilium: RN given refers to parent cpd; structure
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mutations in POLG are a major cause of mitochondrial disorders including hepatic insufficiency, Alpers syndrome, progressive external ophthalmoplegia, sensory neuropathy and ataxia." | 1.43 | Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases. ( Baruffini, E; Delahodde, A; Lodi, T; Pitayu, L; Rodier, C; Rötig, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Facchinello, N | 1 |
| Laquatra, C | 1 |
| Locatello, L | 1 |
| Beffagna, G | 1 |
| Brañas Casas, R | 1 |
| Fornetto, C | 1 |
| Dinarello, A | 1 |
| Martorano, L | 1 |
| Vettori, A | 1 |
| Risato, G | 1 |
| Celeghin, R | 1 |
| Meneghetti, G | 1 |
| Santoro, MM | 1 |
| Delahodde, A | 2 |
| Vanzi, F | 1 |
| Rasola, A | 1 |
| Dalla Valle, L | 1 |
| Rasotto, MB | 1 |
| Lodi, T | 2 |
| Baruffini, E | 2 |
| Argenton, F | 1 |
| Tiso, N | 1 |
| Pitayu, L | 1 |
| Rodier, C | 1 |
| Rötig, A | 1 |
2 other studies available for clofilium and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish.
Topics: Animals; Disease Models, Animal; Mitochondrial Diseases; Phenotype; Quaternary Ammonium Compounds; Z | 2021 |
Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases.
Topics: Animals; Caenorhabditis elegans; DNA Polymerase gamma; DNA Polymerase I; DNA Replication; DNA-Direct | 2016 |