clofilium has been researched along with Bradyarrhythmia in 3 studies
clofilium: RN given refers to parent cpd; structure
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bradycardia is a risk factor for the development of torsade de pointes (TdP)." | 1.35 | Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model. ( Coker, SJ; Dempster, J; Farkas, A, 2008) |
| "In the d,l-sotalol- and erythromycin-treated hearts, torsades de pointes occurred only in the presence of hypokalemia and bradycardia, whereas, in the presence of clofilium, bradycardia alone caused torsades de pointes." | 1.30 | Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin. ( Borggrefe, M; Breithardt, G; Clague, JR; Eckardt, L; Haverkamp, W; Johna, R; Mertens, H, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farkas, A | 1 |
| Dempster, J | 1 |
| Coker, SJ | 1 |
| Yamagishi, T | 1 |
| Ishii, K | 1 |
| Taira, N | 1 |
| Eckardt, L | 1 |
| Haverkamp, W | 1 |
| Mertens, H | 1 |
| Johna, R | 1 |
| Clague, JR | 1 |
| Borggrefe, M | 1 |
| Breithardt, G | 1 |
3 other studies available for clofilium and Bradyarrhythmia
| Article | Year |
|---|---|
Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model.
Topics: Action Potentials; Adrenergic alpha-Agonists; Angiotensin II; Animals; Anti-Arrhythmia Agents; Blood | 2008 |
Antiarrhythmic and bradycardic drugs inhibit currents of cloned K+ channels, KV1.2 and KV1.4.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Cloning, Molecular; Disopyramide; Dose-Response Relati | 1995 |
Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin.
Topics: Animals; Bradycardia; Electrocardiography; Erythromycin; Hypokalemia; In Vitro Techniques; Male; Qua | 1998 |