Page last updated: 2024-10-25

clofibric acid and Pregnancy

clofibric acid has been researched along with Pregnancy in 7 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Clofibrate treatment in vivo (of which clofibric acid is the ester hydrolysis product) had no effect on clofibric acid glucuronidation in vitro."1.27Hepatic microsomal glucuronidation of clofibric acid in the adult and neonate albino rat. ( Odum, J; Orton, TC, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Savas, Ü1
Machemer, DEW1
Hsu, MH1
Gaynor, P1
Lasker, JM1
Tukey, RH1
Johnson, EF1
Wierzbicki, AS1
Mikhailidis, DP1
Wray, R1
Fidaleo, M1
Sartori, C1
Odum, J1
Orton, TC1
Sanfeliu, C1
Zapatero, J1
Bruseghini, L1
de la Fuente, R1
Santos, M1

Reviews

2 reviews available for clofibric acid and Pregnancy

ArticleYear
Drug treatment of combined hyperlipidemia.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2001, Volume: 1, Issue:5

    Topics: Acute Disease; Clofibric Acid; Diabetes Mellitus, Type 2; Female; Fenofibrate; Humans; Hydroxymethyl

2001
Drugs for lipids.
    Treatment guidelines from the Medical Letter, 2005, Volume: 3, Issue:31

    Topics: Anticholesteremic Agents; Apolipoproteins; Azetidines; Bile Acids and Salts; Cholesterol; Cholestero

2005

Other Studies

5 other studies available for clofibric acid and Pregnancy

ArticleYear
Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model.
    The Journal of biological chemistry, 2009, Jun-12, Volume: 284, Issue:24

    Topics: Animals; Clofibric Acid; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Fasting; Female; Fe

2009
Administration of ciprofibrate to lactating mothers induces PPARalpha-signaling pathway in the liver and kidney of suckling rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:1

    Topics: Animals; Animals, Newborn; Animals, Suckling; Apoptosis; Cell Proliferation; Clofibric Acid; Cytochr

2008
Hepatic microsomal glucuronidation of clofibric acid in the adult and neonate albino rat.
    Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23

    Topics: Aging; Animals; Animals, Newborn; Clofibrate; Clofibric Acid; Digitonin; Enzyme Activation; Enzyme I

1983
Toxicological studies of plafibride. Part 3: Study of teratogenic activity in rats and rabbits.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a

    Topics: Animals; Clofibrate; Clofibric Acid; Female; Fetus; Pregnancy; Rabbits; Rats; Rats, Inbred Strains;

1981
[Toxicological and pharmacological studies on a new drug: pirfibrate (EL-466) (author's transl)].
    Archivos de farmacologia y toxicologia, 1980, Volume: 6, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Clofibrate; Clofibric Acid; Diet, Atherogenic; Dogs; Female; F

1980