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clofibric acid and Hyperlipoproteinemia

clofibric acid has been researched along with Hyperlipoproteinemia in 35 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Research Excerpts

ExcerptRelevanceReference
"The effect of long-term treatment over 40 weeks with Bezafibrate on lipids and lipoproteins was investigated in 27 patients with primary hyperlipoproteinemias (hlp) (12 patients with hlp type IV, 7 patients with type IIb, 3 patients with type IIa, 4 patients with type V and 1 patient with type III)."7.66[Bezafibrate in primary hyperlipidemias (author's transl)]. ( Bode, G; Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG, 1982)
"Pirozadil and alufibrate are compared by a single-blind study over two groups 20 patients with primary hyperlipoproteinemia."7.66[Single-blind study of the efficacy of pirozadil versus alufibrate in the treatment of primary hyperlipoproteinemias]. ( Azanza Perea, JR; Honorato Pérez, J, 1982)
"Treatment with ciprofibrate is effective and safe treatment in patients with combined hyperlipoproteinaemia."6.69[Ciprofibrate in the treatment of combined hyperlipoproteinemia. Results in more than 600 patients from 23 centers in the Czech Republic]. ( Ceska, R; Haas, T; Kvasnicka, T; Soska, V; Vaverková, H, 2000)
"Ciprofibrate is an effective hypolipidemic agent, also lowering the level of fibrinogen."5.30[The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. ( Cibulova, L; Fedelesova, V; Gajdos, M; Huttova, D; Krivosikova, Z; Mongiellova, V; Polak, F, 1999)
"The study of the hypolipidemic efficiency, safety and tolerance of ciprofibrate (lipanor) in therapy of atherogenic hyperlipoproteinemia."5.08[Lipanor treatment of atherogenic hyperlipoproteinemia]. ( Arabidze, GG; Kukharchuk, VV; Susekov, AV; Tvorogova, MG, 1998)
"A total of 98 patients selected and classified into type IIa and IIb hyperlipoproteinemia according to Fredrickson and Lees (1965) were pre-treated for 6 months with a commercially available combination product (containing clofibrate and nicotinic acid)."5.05[Therapy of lipoproteinemia. Comparison between Lipo-Merz retard and a commercial combination drug]. ( Steger, W, 1980)
"The effect of long-term treatment over 40 weeks with Bezafibrate on lipids and lipoproteins was investigated in 27 patients with primary hyperlipoproteinemias (hlp) (12 patients with hlp type IV, 7 patients with type IIb, 3 patients with type IIa, 4 patients with type V and 1 patient with type III)."3.66[Bezafibrate in primary hyperlipidemias (author's transl)]. ( Bode, G; Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG, 1982)
"Pirozadil and alufibrate are compared by a single-blind study over two groups 20 patients with primary hyperlipoproteinemia."3.66[Single-blind study of the efficacy of pirozadil versus alufibrate in the treatment of primary hyperlipoproteinemias]. ( Azanza Perea, JR; Honorato Pérez, J, 1982)
"Treatment with ciprofibrate is effective and safe treatment in patients with combined hyperlipoproteinaemia."2.69[Ciprofibrate in the treatment of combined hyperlipoproteinemia. Results in more than 600 patients from 23 centers in the Czech Republic]. ( Ceska, R; Haas, T; Kvasnicka, T; Soska, V; Vaverková, H, 2000)
"Both bezafibrate and EPL were tolerated well."2.65[Treatment of hyperlipoproteinaemia in diabetic patients (author's transl)]. ( Bruneder, H; Klein, HJ, 1981)
"The metabolic syndrome is characterized by atherogenic dyslipidemia (elevated triglycerides, increased small dense low-density lipoproteins, and decreased high-density lipoproteins), hypertension, insulin resistance and obesity."2.41Treatment of dyslipoproteinemia in the metabolic syndrome. ( Fenselau, S; Schrezenmeir, J; Steinmetz, A, 2001)
"Ciprofibrate is an effective treatment for three main types of atherogenic hyperlipoproteinaemia: type IIa hypercholesterolaemia, type IIb combined hyperlipidaemia, and type IV hypertriglyceridaemia."2.39Efficacy and safety of ciprofibrate in hyperlipoproteinaemias. ( Bruckert, E; Turpin, G, 1996)
"Ciprofibrate is an effective hypolipidemic agent, also lowering the level of fibrinogen."1.30[The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. ( Cibulova, L; Fedelesova, V; Gajdos, M; Huttova, D; Krivosikova, Z; Mongiellova, V; Polak, F, 1999)
"Ciprofibrate is a phenoxyisobutyrate derivative with lipid-lowering effects in hyperlipoproteinaemia."1.27Effect of ciprofibrate treatment on biliary lipids in patients with hyperlipoproteinaemia. ( Angelin, B; Einarsson, K; Leijd, B, 1984)
"Ciprofibrate was convenient to take and was without subjective side effects."1.26Dose-response study of the effect of ciprofibrate on serum lipoprotein concentrations in hyperlipoproteinaemia. ( Olsson, AG; Orö, L, 1982)
" The recommended dosage of clofibrate is 1."1.26[Fat and renal failure--therapeutic aspects]. ( Heidland, A; Hörl, M; Hörl, WH, 1982)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199028 (80.00)18.7374
1990's4 (11.43)18.2507
2000's3 (8.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carvalho, AA1
Lima, UW1
Valiente, RA1
Kaffarnik, H2
Schneider, J2
Schubotz, R2
Zöfel, P2
Hausmann, L1
Goebel, KM1
Słowińska, R1
Bochenek, W1
Unlot, J1
Angelin, B1
Einarsson, K1
Leijd, B1
Schatton, W2
Schlierf, G1
Fischer, H1
Roche, A1
Stiehl, A1
Oster, P1
Schellenberg, B1
Vollmar, J2
Prager, R1
Schernthaner, G1
Kostner, GM1
Mühlhauser, I1
Zechner, R1
Dorda, W1
Reuter, W2
Hanefeld, M1
Kemmer, C1
Kadner, E1
Olsson, AG1
Orö, L1
Machalke, K1
Djaja, S1
Richter, E1
Lageder, H1
Dick, TB1
Marples, J1
Ledermann, HM1
Whittington, J1
von Bock und Polach, U1
Wechsler, JG1
Hutt, V1
Klör, HU1
Bode, G1
Ditschuneit, H1
Mertz, DP1
Lang, PD1
Honorato Pérez, J1
Azanza Perea, JR1
Hörl, WH1
Hörl, M1
Heidland, A1
Bruneder, H1
Klein, HJ1
Steger, W1
Noseda, G1
Fragiacomo, C1
Weidmann, P1
Bachmann, C1
Domingo, AJ1
Gutiérrez, JA1
Menéndez, JA1
Micó, L1
Muñoz, M1
de Oya, M1
Schwartzkopff, W1
Schilling, A1
Turpin, G1
Bruckert, E1
Susekov, AV1
Tvorogova, MG1
Arabidze, GG1
Kukharchuk, VV1
Gajdos, M1
Fedelesova, V1
Mongiellova, V1
Cibulova, L1
Huttova, D1
Polak, F1
Krivosikova, Z1
Ceska, R1
Kvasnicka, T1
Haas, T1
Soska, V1
Vaverková, H1
Steinmetz, A1
Fenselau, S1
Schrezenmeir, J1
Bolzano, K1
Krempler, F1
Haslauer, F1
Kłosiewicz-Latoszek, L1
Szostak, WB1
Schulze, J1
Julius, U1
Leonhardt, W1
Haller, H1
Holm, E1

Reviews

2 reviews available for clofibric acid and Hyperlipoproteinemia

ArticleYear
Efficacy and safety of ciprofibrate in hyperlipoproteinaemias.
    Atherosclerosis, 1996, Volume: 124 Suppl

    Topics: Animals; Cardiovascular Diseases; Clofibric Acid; Fibric Acids; Humans; Hyperlipoproteinemias; Hypol

1996
Treatment of dyslipoproteinemia in the metabolic syndrome.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2001, Volume: 109, Issue:4

    Topics: Arteriosclerosis; Clofibric Acid; Coronary Disease; Diabetes Mellitus, Type 2; Gemfibrozil; Humans;

2001

Trials

11 trials available for clofibric acid and Hyperlipoproteinemia

ArticleYear
[Study of the antilipemic effect of etofibrate (Lipo-Merz)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Apr-25, Volume: 38, Issue:17

    Topics: Adult; Aged; Anticholesteremic Agents; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Female;

1983
[Pharmacology and mechanism of action of etofibrate].
    Die Medizinische Welt, 1982, Sep-24, Volume: 33, Issue:38

    Topics: Animals; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemias; Hypoli

1982
[The effect of bezafibrate on biliary lipids (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Feb-01, Volume: 122, Issue:5

    Topics: Adult; Bezafibrate; Bile; Clofibrate; Clofibric Acid; Drug Evaluation; Humans; Hyperlipoproteinemias

1980
Effect of bezafibrate on plasma lipids, lipoproteins, apolipoproteins AI, AII and B and LCAT activity in hyperlipidemic, non-insulin-dependent diabetics.
    Atherosclerosis, 1982, Volume: 43, Issue:2-3

    Topics: Aged; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Bezafibrate; Chole

1982
[Lipid-lowering effect of etofibrate, bezafibrate and xanthinol nicotinate in patients with hyperlipoproteinemias].
    Therapie der Gegenwart, 1982, Volume: 121, Issue:5

    Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibr

1982
[Comparative double-blind investigation of bezafibrate and clofibrate in patients with primary hyperlipoproteinaemia].
    Wiener klinische Wochenschrift, 1980, Feb-01, Volume: 92, Issue:3

    Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Male; P

1980
Comparative study of once and 3-times daily regimens of bezafibrate in patients with primary hyperlipoproteinaemia.
    Current medical research and opinion, 1981, Volume: 7, Issue:8

    Topics: Adult; Aged; Alkaline Phosphatase; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; C

1981
[Treatment of hyperlipoproteinaemia in diabetic patients (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Dec-04, Volume: 106, Issue:49

    Topics: Adult; Aged; Bezafibrate; Blood Glucose; Cholesterol; Clofibrate; Clofibric Acid; Diabetes Complicat

1981
[Therapy of lipoproteinemia. Comparison between Lipo-Merz retard and a commercial combination drug].
    Fortschritte der Medizin, 1980, May-15, Volume: 98, Issue:18

    Topics: Adult; Aged; Cholesterol; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Drug Combinations

1980
[Lipanor treatment of atherogenic hyperlipoproteinemia].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:9

    Topics: Cholesterol; Clofibric Acid; Coronary Artery Disease; Disease Progression; Drug Administration Sched

1998
[Ciprofibrate in the treatment of combined hyperlipoproteinemia. Results in more than 600 patients from 23 centers in the Czech Republic].
    Vnitrni lekarstvi, 2000, Volume: 46, Issue:3

    Topics: Clofibric Acid; Female; Fibric Acids; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Mid

2000

Other Studies

22 other studies available for clofibric acid and Hyperlipoproteinemia

ArticleYear
Statin and fibrate associated myopathy: study of eight patients.
    Arquivos de neuro-psiquiatria, 2004, Volume: 62, Issue:2A

    Topics: Adult; Aged; Anticholesteremic Agents; Biopsy; Clofibric Acid; Creatine Kinase; Drug Therapy, Combin

2004
Long-term treatment of hyperlipoproteinemia with etofibrate: clinical observations.
    Artery, 1980, Volume: 8, Issue:6

    Topics: Adult; Aged; Cholesterol; Clofibrate; Clofibric Acid; Creatine Kinase; Female; gamma-Glutamyltransfe

1980
Effect of ciprofibrate treatment on biliary lipids in patients with hyperlipoproteinaemia.
    European journal of clinical investigation, 1984, Volume: 14, Issue:1

    Topics: Adult; Aged; Bile; Bile Acids and Salts; Cholesterol; Clofibrate; Clofibric Acid; Female; Fibric Aci

1984
[Longterm therapy and etofibrate (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Jan-18, Volume: 122, Issue:3

    Topics: Anticholesteremic Agents; Blood Cell Count; Blood Glucose; Clofibrate; Clofibric Acid; Drug Administ

1980
[Effect of combination therapy of clofibric acid and nicotinic acid derivatives on fatty acid metabolism in hyperlipoproteinemia].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Oct-15, Volume: 37, Issue:20

    Topics: Aged; Clofibrate; Clofibric Acid; Drug Therapy, Combination; Fatty Acids; Female; Humans; Hyperlipop

1982
Relationship between morphological changes and lipid-lowering action of p-chlorphenoxyisobutyric acid (CPIB) on hepatic mitochondria and peroxisomes in man.
    Atherosclerosis, 1983, Volume: 46, Issue:2

    Topics: Adult; Aged; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Male; Microbodies; M

1983
Dose-response study of the effect of ciprofibrate on serum lipoprotein concentrations in hyperlipoproteinaemia.
    Atherosclerosis, 1982, Volume: 42, Issue:2-3

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Sedimentation; Body Weight; Cholesterol; Ch

1982
[Lowering lipids rapidly and permanently with etofibrate].
    Medizinische Klinik, 1982, Jan-29, Volume: 77, Issue:3

    Topics: Cholestyramine Resin; Clofibrate; Clofibric Acid; Dextrothyroxine; Humans; Hyperlipoproteinemias; Li

1982
[Bezafibrate in primary hyperlipidemias (author's transl)].
    Klinische Wochenschrift, 1982, Jan-15, Volume: 60, Issue:2

    Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Female; Hu

1982
Bezafibrate: lack of effect on creatinine excretion and muscular proteins.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1982, Volume: 180, Issue:1

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Creatine Kinase; Creatinine; Female; Humans; Hyperlipoprote

1982
[Single-blind study of the efficacy of pirozadil versus alufibrate in the treatment of primary hyperlipoproteinemias].
    Revista de medicina de la Universidad de Navarra, 1982, Volume: 26, Issue:1

    Topics: Cholesterol; Clofibrate; Clofibric Acid; Drug Evaluation; Female; Humans; Hyperlipoproteinemias; Lip

1982
[Fat and renal failure--therapeutic aspects].
    Klinische Wochenschrift, 1982, Volume: 60, Issue:15

    Topics: Acute Kidney Injury; Animals; Bezafibrate; Carnitine; Charcoal; Clofibrate; Clofibric Acid; Humans;

1982
[Current treatment with clofibrate or clofibric acid (Regadrin)].
    Zeitschrift fur arztliche Fortbildung, 1982, May-15, Volume: 76, Issue:10

    Topics: Cholelithiasis; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hypercholesterolemia; Hyperlipoprot

1982
[What is important in therapy of hyperlipoproteinemia. Lipo-Merz retard (etofibrate) lowers the atherogenic index].
    Fortschritte der Medizin, 1982, Sep-16, Volume: 100, Issue:35

    Topics: Anticholesteremic Agents; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Humans; Hyperlipo

1982
[The therapeutic efficacy of bezafibrate in hyperlipoproteinemias of various types].
    Schweizerische medizinische Wochenschrift, 1980, Dec-06, Volume: 110, Issue:49

    Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type II; Hyperlip

1980
Pirifibrate in the treatment of hyperlipoproteinemias: a multicenter study.
    Clinical therapeutics, 1980, Volume: 3, Issue:3

    Topics: Adult; Aged; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type

1980
[Comparative research on etofibrate retard and fenofibrate in hyperlipoproteinemia].
    Die Medizinische Welt, 1980, Dec-12, Volume: 31, Issue:50

    Topics: Aged; Cholesterol; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Female; Fenofibrate; Hum

1980
[The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:8

    Topics: Aged; Arteriosclerosis; Aspirin; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Fi

1999
[Treatment of various types of hyperlipoproteinaemia with a combination of Mg-chlorophenoxy-isobutyrate and mesoinositol-hexanicotinate (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:10

    Topics: Adult; Aged; Cholesterol; Clofibrate; Clofibric Acid; Drug Combinations; Female; Humans; Hyperlipopr

1979
Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:1

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Colestipol; Female; Fenofibrate;

1991
[Metabolism kinetic characterization of hypertriglyceridemias in drug therapy variations].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1987, Sep-15, Volume: 42, Issue:18

    Topics: Adult; Blood Glucose; Buformin; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Delayed-Action P

1987
[Etofibrate in severe diet-refractory cases of hyperlipoproteinemia].
    Fortschritte der Medizin, 1986, Apr-03, Volume: 104, Issue:13

    Topics: Adult; Aged; Cholesterol; Clofibrate; Clofibric Acid; Dietary Fats; Female; Humans; Hyperlipoprotein

1986