Page last updated: 2024-10-25

clofibric acid and Hyperhomocysteinemia

clofibric acid has been researched along with Hyperhomocysteinemia in 2 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (

Research Excerpts

ExcerptRelevanceReference
"To test the hypothesis that endothelial dysfunction in hyperhomocysteinemia was due to increased levels of nitrotyrosine and matrix metalloproteinase (MMP) activity in response to antagonism of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), cystathionine beta-synthase (CBS) -/+ mice were bred, tail tissue was analyzed for genotype by PCR, and tail vein blood was analyzed for homocysteine (Hcy) by spectrofluorometry."7.72Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia. ( Hunt, MJ; Sood, HS; Tyagi, SC, 2003)
"To test the hypothesis that endothelial dysfunction in hyperhomocysteinemia was due to increased levels of nitrotyrosine and matrix metalloproteinase (MMP) activity in response to antagonism of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), cystathionine beta-synthase (CBS) -/+ mice were bred, tail tissue was analyzed for genotype by PCR, and tail vein blood was analyzed for homocysteine (Hcy) by spectrofluorometry."3.72Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia. ( Hunt, MJ; Sood, HS; Tyagi, SC, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sood, HS1
Hunt, MJ1
Tyagi, SC1
Lacut, K1
Le Gal, G1
Abalain, JH1
Mottier, D1
Oger, E1

Other Studies

2 other studies available for clofibric acid and Hyperhomocysteinemia

ArticleYear
Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:2

    Topics: Animals; Aorta; Blood Pressure; Clofibric Acid; Cystathionine beta-Synthase; Endothelium, Vascular;

2003
Differential associations between lipid-lowering drugs, statins and fibrates, and venous thromboembolism: role of drug induced homocysteinemia?
    Thrombosis research, 2008, Volume: 122, Issue:3

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Clofibric Acid; Databases, Factual; Female; Homocyste

2008