clofibric acid has been researched along with Hepatoblastoma in 2 studies
Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.
Hepatoblastoma: A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
Excerpt | Relevance | Reference |
---|---|---|
"We have examined the ability of HepG2 human hepatoblastoma cells and 7800 C1 Morris rat hepatoma cells to convert 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid (THCA) and 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) to cholic acid and chenodeoxycholic acid, respectively." | 3.68 | Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation. ( Farrants, AK; Nilsson, A; Pedersen, JI, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Farrants, AK | 1 |
Nilsson, A | 1 |
Pedersen, JI | 1 |
Duclos, S | 1 |
Bride, J | 1 |
Ramirez, LC | 1 |
Bournot, P | 1 |
2 other studies available for clofibric acid and Hepatoblastoma
Article | Year |
---|---|
Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholesterol 7-alpha-Hydroxylase; | 1993 |
Peroxisome proliferation and beta-oxidation in Fao and MH1C1 rat hepatoma cells, HepG2 human hepatoblastoma cells and cultured human hepatocytes: effect of ciprofibrate.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Cells, Cultured; Clofibric Acid; Enoyl-CoA Hydratase; Fen | 1997 |