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clofibric acid and Fatty Liver

clofibric acid has been researched along with Fatty Liver in 5 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
" Dyslipidemia in patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis may improve with use of statins, fibrates, niacin, and thiazolidinediones, but the data are presently very limited."4.82Management of dyslipidemia in patients with complicated metabolic syndrome. ( Davidson, MH, 2005)
"Fenofibrate treatment decreased hepatic macrophage accumulation and abolished steatosis."1.33Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. ( Buffat, L; Gijbels, MJ; Hofker, MH; Maeda, N; Noel, B; Shiri-Sverdlov, R; Staels, B; van Bilsen, M; van Gorp, PJ; Wouters, K, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karahashi, M1
Hoshina, M1
Yamazaki, T1
Sakamoto, T1
Mitsumoto, A1
Kawashima, Y1
Kudo, N1
Hwang, B1
Wu, P1
Harris, RA1
Davidson, MH1
Shiri-Sverdlov, R1
Wouters, K1
van Gorp, PJ1
Gijbels, MJ1
Noel, B1
Buffat, L1
Staels, B1
Maeda, N1
van Bilsen, M1
Hofker, MH1
Miyazawa, S1
Furuta, S1
Hashimoto, T1

Reviews

1 review available for clofibric acid and Fatty Liver

ArticleYear
Management of dyslipidemia in patients with complicated metabolic syndrome.
    The American journal of cardiology, 2005, Aug-22, Volume: 96, Issue:4A

    Topics: Clofibric Acid; Fatty Liver; HIV-Associated Lipodystrophy Syndrome; Humans; Hydroxymethylglutaryl-Co

2005

Other Studies

4 other studies available for clofibric acid and Fatty Liver

ArticleYear
Fibrates reduce triacylglycerol content by upregulating adipose triglyceride lipase in the liver of rats.
    Journal of pharmacological sciences, 2013, Volume: 123, Issue:4

    Topics: Animals; Bezafibrate; Clofibric Acid; Fatty Liver; Fenofibrate; Lipase; Lipid Peroxidation; Liver; M

2013
Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet.
    The FEBS journal, 2012, Volume: 279, Issue:10

    Topics: Animals; Clofibric Acid; Diet, High-Fat; Fatty Liver; Hypolipidemic Agents; Isoenzymes; Mice; Mice,

2012
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates.
    Journal of hepatology, 2006, Volume: 44, Issue:4

    Topics: Animals; Apolipoprotein E2; Apolipoproteins E; ATP-Binding Cassette Transporters; Clofibric Acid; Di

2006
Reduction of beta-oxidation capacity of rat liver mitochondria by feeding orotic acid.
    Biochimica et biophysica acta, 1982, Jun-11, Volume: 711, Issue:3

    Topics: Acyl-CoA Dehydrogenases; Adenine; Animals; Clofibric Acid; Diet; Fatty Acids; Fatty Liver; Male; Mit

1982