clofibric acid has been researched along with Enlarged Liver in 8 studies
Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ciprofibrate was fed at concentrations ranging from 0." | 1.28 | Dose-response relationships of hepatic acyl-CoA oxidase and catalase activity and liver mitogenesis induced by the peroxisome proliferator ciprofibrate in C57BL/6N and BALB/c mice. ( Angeloff, K; Budroe, JD; Umemura, T; Williams, GM, 1992) |
| " The effects of different dosing regimens of three hypolipidaemic, peroxisome-proliferator drugs on hepatic enzymes in the Fischer rat following 26 weeks treatment have been studied." | 1.28 | Hepatic induction potency of hypolipidaemic drugs in the rat following long-term administration: influence of different dosing regimens. ( Bonner, FW; Gibson, GG; Makowska, JM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawashima, Y | 1 |
| Katoh, H | 1 |
| Kozuka, H | 1 |
| Lazarow, PB | 1 |
| Shio, H | 1 |
| Leroy-Houyet, MA | 1 |
| Yamoto, T | 1 |
| Ohashi, Y | 1 |
| Teranishi, M | 1 |
| Takaoka, M | 1 |
| Manabe, S | 1 |
| Matsunuma, N | 1 |
| Makita, T | 1 |
| Nishimaki-Mogami, T | 1 |
| Takahashi, A | 1 |
| Toyoda, K | 1 |
| Hayashi, Y | 1 |
| Barrass, NC | 1 |
| Price, RJ | 1 |
| Lake, BG | 2 |
| Orton, TC | 1 |
| Budroe, JD | 1 |
| Umemura, T | 1 |
| Angeloff, K | 1 |
| Williams, GM | 1 |
| Makowska, JM | 1 |
| Bonner, FW | 1 |
| Gibson, GG | 1 |
| Kozlen, SL | 1 |
| Evans, JG | 1 |
| Gray, TJ | 1 |
| Young, PJ | 1 |
| Gangolli, SD | 1 |
8 other studies available for clofibric acid and Enlarged Liver
| Article | Year |
|---|---|
Differential effects of altered hormonal state on the induction of acyl-CoA hydrolases and peroxisomal beta-oxidation by clofibric acid.
Topics: Adrenalectomy; Animals; Clofibrate; Clofibric Acid; Dexamethasone; Diabetes Mellitus, Experimental; | 1983 |
Specificity in the action of hypolipidemic drugs: increase of peroxisomal beta-oxidation largely dissociated from hepatomegaly and peroxisome proliferation in the rat.
Topics: Animals; Bezafibrate; Cell Division; Cell Fractionation; Clofibrate; Clofibric Acid; Female; Hepatom | 1982 |
Age-related changes in the susceptibility to clofibric acid, a hypolipidemic agent, of male rat liver.
Topics: Administration, Oral; Aging; Animals; Body Weight; Cholesterol; Clofibric Acid; Cytochrome P-450 Enz | 1995 |
Induction of peroxisomal beta-oxidation by a microbial catabolite of cholic acid in rat liver and cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Cholic Acid; Cholic Acids; Clofibric Acid; Enzyme Induction; Fatty Acids; | 1993 |
Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Division; Clofenapate; Clofibric Acid; DNA; Hepatomega | 1993 |
Dose-response relationships of hepatic acyl-CoA oxidase and catalase activity and liver mitogenesis induced by the peroxisome proliferator ciprofibrate in C57BL/6N and BALB/c mice.
Topics: Acyl-CoA Oxidase; Administration, Oral; Animals; Catalase; Clofibric Acid; Dose-Response Relationshi | 1992 |
Hepatic induction potency of hypolipidaemic drugs in the rat following long-term administration: influence of different dosing regimens.
Topics: Animals; Bezafibrate; Clofibric Acid; Fibric Acids; Glutathione Peroxidase; Hepatomegaly; Hypolipide | 1990 |
Effect of prolonged administration of clofibric acid and di-(2-ethylhexyl)phthalate on hepatic enzyme activities and lipid peroxidation in the rat.
Topics: Animals; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Hepatomegaly; Lipid Peroxides; Liver; M | 1987 |