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clofibric acid and Drug Overdose

clofibric acid has been researched along with Drug Overdose in 2 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"(1) Renal failure, either pre-existing or induced by a nephrotoxic drug, increases the risk of adverse effects in patients taking colchicine; (2) Combining colchicines with a macrolide (except for spiramycin) carries a risk of life-threatening pancytopenia; (3) Ciclosporin co-administration can aggravate the neuromuscular adverse effects of colchicine; (4) Combining colchicine with lipid-lowering drugs (statins and fibrates) can cause myopathy; (5) Several mechanisms have been implicated: competition for cytochrome P450 or P-glycoprotein, additive adverse effects (especially on muscle), and colchicine accumulation due to a reduction in its renal excretion; (6) Patients with gout should use colchicine only after failure of symptomatic treatment: ice application, paracetamol, and possibly ibuprofen, a nonsteroidal antiinflammatory drug with well-documented adverse effects; (7) If colchicine is nevertheless used, it should be at the minimum effective dose."3.74Colchicine: serious interactions. ( , 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giraud, O1
Chanu, B1
Farge, D1
Parrot, F1
Brestescher, C1
Rouffy, J1

Other Studies

2 other studies available for clofibric acid and Drug Overdose

ArticleYear
Colchicine: serious interactions.
    Prescrire international, 2008, Volume: 17, Issue:96

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Clofibric Acid; Colchicine; Cycl

2008
[Acute rhabdomyolysis associated with digestive disorders during a voluntary overdose of ciprofibrate].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:2

    Topics: Abdominal Pain; Acute Disease; Adult; Clofibric Acid; Diarrhea; Drug Overdose; Fibric Acids; Humans;

1995