Page last updated: 2024-10-25

clofibric acid and Disease Models, Animal

clofibric acid has been researched along with Disease Models, Animal in 9 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Fenofibrate treatment decreased hepatic macrophage accumulation and abolished steatosis."1.33Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. ( Buffat, L; Gijbels, MJ; Hofker, MH; Maeda, N; Noel, B; Shiri-Sverdlov, R; Staels, B; van Bilsen, M; van Gorp, PJ; Wouters, K, 2006)
"Clofibric acid (CL) is a compound used to control hypertriglyceridemia, and ethacrynic acid (ET) is administered to enhance diuresis."1.33Aryloxoalcanoic compounds induce resistance to antibiotic therapy in urinary tract infection caused by Escherichia coli. ( Balagué, C; De Duffard, AM; De Ruiz, CS; Duffard, R; Nader-Macías, ME; Rey, R; Stürtz, N, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Maiguma, T1
Fujisaki, K1
Itoh, Y1
Makino, K1
Teshima, D1
Takahashi-Yanaga, F1
Sasaguri, T1
Oishi, R1
Shiri-Sverdlov, R1
Wouters, K1
van Gorp, PJ1
Gijbels, MJ1
Noel, B1
Buffat, L1
Staels, B1
Maeda, N1
van Bilsen, M1
Hofker, MH1
Balagué, C1
Stürtz, N1
Rey, R1
De Ruiz, CS1
Nader-Macías, ME1
Duffard, R1
De Duffard, AM1
Yokoyama, Y1
Xin, B1
Shigeto, T1
Umemoto, M1
Kasai-Sakamoto, A1
Futagami, M1
Tsuchida, S1
Al-Mulla, F1
Mizunuma, H1
Betz, E1
Quack, G1
Mohan, PF1
Cleary, MP1
Kasiske, BL1
O'Donnell, MP1
Garvis, WJ1
Keane, WF1
Wirth, PJ1
Rao, MS1
Evarts, RP1

Other Studies

9 other studies available for clofibric acid and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric

2003
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates.
    Journal of hepatology, 2006, Volume: 44, Issue:4

    Topics: Animals; Apolipoprotein E2; Apolipoproteins E; ATP-Binding Cassette Transporters; Clofibric Acid; Di

2006
Aryloxoalcanoic compounds induce resistance to antibiotic therapy in urinary tract infection caused by Escherichia coli.
    FEMS immunology and medical microbiology, 2006, Volume: 48, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Clofibric Acid; Disease Models, Animal; Diuretics; Drug Int

2006
Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:4

    Topics: Alcohol Oxidoreductases; Animals; Anticholesteremic Agents; Apoptosis; Ascites; Cell Line, Tumor; Ce

2007
Effect of etofibrate on the development and the regression of atheromas in a rabbit model of atherosclerosis.
    VASA. Zeitschrift fur Gefasskrankheiten, 1990, Volume: 19, Issue:2

    Topics: Animals; Arteriosclerosis; Clofibrate; Clofibric Acid; Disease Models, Animal; Hypolipidemic Agents;

1990
Comparison of dehydroepiandrosterone and clofibric acid treatments in obese Zucker rats.
    The Journal of nutrition, 1989, Volume: 119, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Clofibrate; Clofibric Acid; Dehydroepiandrosterone; Disease Mod

1989
Pharmacologic treatment of hyperlipidemia reduces glomerular injury in rat 5/6 nephrectomy model of chronic renal failure.
    Circulation research, 1988, Volume: 62, Issue:2

    Topics: Animals; Cholesterol; Clofibrate; Clofibric Acid; Disease Models, Animal; Glomerulonephritis; Glomer

1988
Coordinate polypeptide expression during hepatocarcinogenesis in male F-344 rats: comparison of the Solt-Farber and Reddy models.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Animals; Clofibric Acid; Computers; Cytosol; Diethylnitrosamine; Dihydrolipoamide Dehydrogenase; Dis

1987