Page last updated: 2024-10-25

clofibric acid and Aging

clofibric acid has been researched along with Aging in 5 studies

Clofibric Acid: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
clofibric acid : A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Clofibrate treatment in vivo (of which clofibric acid is the ester hydrolysis product) had no effect on clofibric acid glucuronidation in vitro."1.27Hepatic microsomal glucuronidation of clofibric acid in the adult and neonate albino rat. ( Odum, J; Orton, TC, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnaud, J1
Akbaraly, TN1
Hininger-Favier, I1
Berr, C1
Roussel, AM1
Odum, J1
Orton, TC1
Calatayud, JM1
Verbeeck, RK1
Wallace, SM1
Loewen, GR1
Yamoto, T1
Ohashi, Y1
Teranishi, M1
Takaoka, M1
Manabe, S1
Matsunuma, N1
Makita, T1

Other Studies

5 other studies available for clofibric acid and Aging

ArticleYear
Fibrates but not statins increase plasma selenium in dyslipidemic aged patients--the EVA study.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2009, Volume: 23, Issue:1

    Topics: Aged; Aging; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Dyslipidemias; Female; Humans; Hydr

2009
Hepatic microsomal glucuronidation of clofibric acid in the adult and neonate albino rat.
    Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23

    Topics: Aging; Animals; Animals, Newborn; Clofibrate; Clofibric Acid; Digitonin; Enzyme Activation; Enzyme I

1983
Favorable effects of the lipid-lowering and platelet antiaggregant Plafibride on the aging process of mice of the C57bl/6J strain.
    Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:10

    Topics: Aging; Animal Feed; Animals; Body Weight; Clofibrate; Clofibric Acid; Hypolipidemic Agents; Lipofusc

1983
Reduced elimination of ketoprofen in the elderly is not necessarily due to impaired glucuronidation.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:6

    Topics: Aged; Aging; Clofibric Acid; Diflunisal; Glucuronates; Humans; Ketoprofen; Phenylpropionates; Proben

1984
Age-related changes in the susceptibility to clofibric acid, a hypolipidemic agent, of male rat liver.
    Toxicology letters, 1995, Volume: 78, Issue:2

    Topics: Administration, Oral; Aging; Animals; Body Weight; Cholesterol; Clofibric Acid; Cytochrome P-450 Enz

1995