Page last updated: 2024-10-25

clofibrate and Uremia

clofibrate has been researched along with Uremia in 12 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Clofibrate has particular dangers in patients with uraemia or hypoproteinaemia, and we recommend that it be used with great caution in patients with renal disease."1.26Clofibrate-induced complications in renal disease: a case report. ( Gregory, MC; Pokroy, N; Ress, S, 1977)
" The most appropriate drug, clofibrate, is renally excreted and can be used safely if the dosage is markedly reduced."1.26Uremic hyperlipidemia: the nature of the problem. ( Brunzell, JD; Sherrard, DJ, 1977)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Robertz, GM1
Dengler, HJ1
Giorcelli, G1
Vacha, G1
Icardi, GP1
Bjornsson, TD1
Meffin, PJ1
Peters, FA1
Blaschke, TF1
Pokroy, N1
Ress, S1
Gregory, MC1
Sherrard, DJ2
Brunzell, JD2
Kijima, Y1
Sasaoka, T1
Kanayama, M1
Kubota, S1
Goldberg, AP1
Haas, LB1
Bruderlein, H1
Robinson, WT1
Kraml, M1
Dvornik, D1
Drüeke, TB1
Pujade-Lauraine, E1
Poisson, M1
Zingraff, J1
Ulmann, A1
Crosnier, J1
Calvo, R1
Carlos, R1
Erill, S1
O'Reilly, RA1
Aggeler, PM1
Hellem, AJ1

Reviews

2 reviews available for clofibrate and Uremia

ArticleYear
Determinants of the response to oral anticoagulant drugs in man.
    Pharmacological reviews, 1970, Volume: 22, Issue:1

    Topics: Administration, Oral; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anticoagulants; Blood

1970
Metabolic disorders of platelets.
    Advances in internal medicine, 1971, Volume: 17

    Topics: Adenine; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Cell Aggregation; Clofibrate; Fi

1971

Other Studies

10 other studies available for clofibrate and Uremia

ArticleYear
Endogenous ligand(s) decrease drug--protein binding in uremic sera: a fluorescence probe study.
    Klinische Wochenschrift, 1983, Jul-01, Volume: 61, Issue:13

    Topics: Adult; Clofibrate; Clofibric Acid; Dansyl Compounds; Female; Fluorescent Dyes; Glycine; Humans; Kidn

1983
Drug treatment of hypertriglyceridaemia in chronic uraemic patients: preliminary report on D,L-carnitine and thiadenol.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1980, Volume: 17

    Topics: Carnitine; Chronic Disease; Clofibrate; Fatty Alcohols; Humans; Hyperlipoproteinemias; Lipid Metabol

1980
Saliva and plasma levels and plasma protein binding of clofibrinic acid in uremic patients.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:2

    Topics: Adult; Aged; Blood Proteins; Clofibrate; Clofibric Acid; Humans; Kidney Failure, Chronic; Middle Age

1980
Clofibrate-induced complications in renal disease: a case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Nov-05, Volume: 52, Issue:20

    Topics: Adult; Clofibrate; Humans; Male; Muscular Diseases; Nephrotic Syndrome; Peripheral Nervous System Di

1977
Uremic hyperlipidemia: the nature of the problem.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1977, Volume: 7

    Topics: Cholesterol; Clofibrate; Humans; Hyperlipidemias; Lipoproteins, HDL; Renal Dialysis; Uremia

1977
Untoward effects of clofibrate in hemodialyzed patients.
    The New England journal of medicine, 1977, Mar-03, Volume: 296, Issue:9

    Topics: Clofibrate; Humans; Hyperlipidemias; Muscular Diseases; Renal Dialysis; Uremia

1977
Control of clofibrate toxicity in uremic hypertriglyceridemia.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:3

    Topics: Adult; Cholesterol; Clofibrate; Creatine Kinase; Dose-Response Relationship, Drug; Drug Administrati

1977
A gas-liquid chromatographic determination of p-chlorophenoxyisobutyric acid and its comparison to an ultra violet method.
    Clinical biochemistry, 1975, Volume: 8, Issue:4

    Topics: Animals; Chromatography, Gas; Clofibrate; Dogs; Humans; Nephrosis; Rats; Spectrophotometry, Ultravio

1975
Measles virus and Guillain-Barré syndrome during long-term hemodialysis.
    The American journal of medicine, 1976, Volume: 60, Issue:3

    Topics: Adult; Antibodies, Viral; Clofibrate; Humans; Male; Measles; Measles virus; Polyradiculopathy; Renal

1976
Underestimation of albumin content by bromocresol green, induced by drug displacers and uremia.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:2

    Topics: Adult; Bromcresol Green; Clofibrate; Clofibric Acid; Cresols; Electrophoresis, Cellulose Acetate; Hu

1985