clofibrate has been researched along with Neoplasms in 26 studies
angiokapsul: contains clofibrate & insoitolnicotinate
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "Sphingosine kinase (SphK) is an oncogenic lipid kinase that regulates the sphingolipid metabolic pathway that has been shown to play a role in numerous hyperproliferative/inflammatory diseases." | 2.50 | Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. ( Amin, S; Plano, D; Sharma, AK, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willson, TM | 1 |
| Brown, PJ | 1 |
| Sternbach, DD | 1 |
| Henke, BR | 1 |
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Plano, D | 1 |
| Amin, S | 1 |
| Sharma, AK | 1 |
| Penna, F | 1 |
| Bonelli, G | 1 |
| Baccino, FM | 1 |
| Costelli, P | 1 |
| Oliver, MF | 2 |
| Heller, RF | 1 |
| Heller, F | 1 |
| Pourbaix, S | 1 |
| Epstein, LH | 1 |
| Fabbrocini, V | 1 |
| Boumendil, EF | 1 |
| Balkau, B | 1 |
| Charles, MA | 1 |
| Eschwège, E | 1 |
| Downie, CC | 1 |
| Dilman, VM | 2 |
| Gianoulakis, C | 1 |
| Nestruck, AC | 1 |
| Lis, M | 1 |
| Davignon, J | 1 |
| Chrétien, M | 1 |
| Wedel, H | 1 |
| Vedin, A | 1 |
| Wilhelmsen, L | 1 |
| de Gennes, JL | 1 |
| Schiffman, FJ | 1 |
| Fisher, JM | 1 |
| Rabinovitz, M | 1 |
| Dil'man, VM | 1 |
| Bershteĭn, LM | 1 |
| Tsyrlina, EV | 1 |
| Bobrov, IuF | 1 |
| Kovaleva, IG | 2 |
| Revskoy, SY | 1 |
| Poroshina, TE | 1 |
| Berstein, LM | 1 |
| Ostroumova, MN | 1 |
| Fenwick, GR | 1 |
| Hanley, AB | 1 |
8 reviews available for clofibrate and Neoplasms
| Article | Year |
|---|---|
The PPARs: from orphan receptors to drug discovery.
Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligand | 2000 |
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors.
Topics: Clofibrate; Drug Combinations; Enzyme Inhibitors; Humans; Isoenzymes; Lysophospholipids; Neoplasms; | 2014 |
Cytotoxic properties of clofibrate and other peroxisome proliferators: relevance to cancer progression.
Topics: Animals; Clofibrate; Cytotoxins; Disease Progression; Humans; Neoplasms; Peroxisome Proliferator-Act | 2010 |
[Peroxisomes and hypolipidemic agents ].
Topics: Animals; Clofibrate; Cricetinae; Energy Metabolism; Female; Humans; Hydrogen Peroxide; Hypolipidemic | 1982 |
The direct effects of compliance on health outcome.
Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug T | 1984 |
The genus Allium--Part 3.
Topics: Allium; Animals; Arteriosclerosis; Asthma; Bacteria; Blood Glucose; Blood Protein Electrophoresis; C | 1985 |
7 trials available for clofibrate and Neoplasms
| Article | Year |
|---|---|
WHO cooperative trial on primary prevention of ischaemic heart disease with clofibrate to lower serum cholesterol: final mortality follow-up. Report of the Committee of Principal Investigators.
Topics: Cholesterol; Clinical Trials as Topic; Clofibrate; Coronary Disease; Follow-Up Studies; Humans; Male | 1984 |
The direct effects of compliance on health outcome.
Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug T | 1984 |
Clofibrate.
Topics: Clinical Trials as Topic; Clofibrate; Coronary Disease; Drug Evaluation; Humans; Hyperlipidemias; Ne | 1979 |
A co-operative trial in the primary prevention of ischaemic heart disease using clofibrate. Report from the Committee of Principal Investigators.
Topics: Adult; Cardiovascular Diseases; Cholelithiasis; Cholesterol; Clinical Trials as Topic; Clofibrate; C | 1978 |
Cholesterol, coronaries, clofibrate and death.
Topics: Adult; Cholesterol; Clinical Trials as Topic; Clofibrate; Coronary Disease; Death, Sudden; Humans; H | 1978 |
[Increased mortality with clofibrate].
Topics: Adult; Cardiovascular Diseases; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Humans; M | 1979 |
[Real or alleged risks of clofibrate derivatives and certain risks of their prohibition].
Topics: Adult; Arteriosclerosis; Cholelithiasis; Clinical Trials as Topic; Clofibrate; Coronary Disease; Eur | 1979 |
12 other studies available for clofibrate and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Cholesterol-lowering and cancer in the prevention of cardiovascular disease.
Topics: Cardiovascular Diseases; Clofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperch | 2010 |
The clofibrate problem: a different viewpoint.
Topics: Animals; Biotransformation; Clofibrate; Coronary Disease; Humans; Neoplasms; Phenoxyacetates; Rats | 1980 |
Coronary heart disease, cancer, lipoproteins, and the effects of clofibrate: is enzyme induction a common link and are lipoproteins red herrings?
Topics: Carcinogens; Cholesterol; Cholesterol, HDL; Clofibrate; Coronary Disease; Enzyme Induction; Humans; | 1981 |
[Study of clofibrate. The opinion of Prof. D. Kritchevsky].
Topics: Adult; Arteriosclerosis; Cholelithiasis; Clofibrate; Coronary Disease; Drug Evaluation; Humans; Hype | 1980 |
Mortality from non-cardiovascular disease and diabetes mellitus.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cause of Death; Clofibrate; Diabetes Mellitus; Fr | 1998 |
High death rate from neoplasms in French diabetic and non-diabetic men.
Topics: Case-Control Studies; Clofibrate; Diabetes Mellitus; Humans; Hyperlipidemias; Hypolipidemic Agents; | 1998 |
Ageing, metabolic immunodepression and carcinogenesis.
Topics: Adult; Aged; Aging; Cell Transformation, Neoplastic; Cholesterol; Clofibrate; Coronary Disease; Diab | 1978 |
Experimental hyperlipidemia in rats.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Blood Pressure; Cholesterol; Clofibrate; Cycli | 1979 |
Serum displacing agents in cancer chemotherapy.
Topics: Animals; Cattle; Cells, Cultured; Chemical Phenomena; Chemistry; Chlorambucil; Clofibrate; Culture M | 1977 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C | 1975 |
Age-dependent metabolic immunodepression and cancer.
Topics: Age Factors; Biguanides; Blood Viscosity; Breast Neoplasms; Cholesterol; Clofibrate; Female; Humans; | 1985 |