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clofibrate and Necrosis

clofibrate has been researched along with Necrosis in 9 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart."7.66Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)
" To examine the role of stimulated FAO during ischemia, Etomoxir (Eto), clofibrate, and WY-14,643 compounds were given 5 days prior to the induction of ischemia/reperfusion (I/R) injury."3.70Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure. ( Crew, MD; Dai, G; Gonzalez, FJ; Peters, JM; Portilla, D; Proia, AD, 2000)
"Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart."3.66Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, C2
Hennig, GE2
Whiteley, HE2
Manautou, JE3
Hoivik, DJ1
Tveit, A1
Hart, SG1
Khairallah, EA1
Cohen, SD1
Portilla, D1
Dai, G1
Peters, JM1
Gonzalez, FJ1
Crew, MD1
Proia, AD1
Corton, JC1
Kumamoto, T1
Wexler, BC1
Greenberg, BP1
Savoie, LL1
Haft, JI1
Kranz, PD1
Albert, F1
Oestreicher, R1
Wilke, H1
Frahm, H1
Zsernaviezky, J1
von Torklus, D1

Reviews

1 review available for clofibrate and Necrosis

ArticleYear
[Necrotizing myopathies].
    Ryoikibetsu shokogun shirizu, 2001, Issue:36

    Topics: Acute Disease; Aminocaproic Acid; Anti-Inflammatory Agents; Clofibrate; Diagnosis, Differential; Hum

2001

Other Studies

8 other studies available for clofibrate and Necrosis

ArticleYear
Protection against acetaminophen hepatotoxicity by clofibrate pretreatment: role of catalase induction.
    Journal of biochemical and molecular toxicology, 2002, Volume: 16, Issue:5

    Topics: Acetaminophen; Administration, Oral; Amitrole; Analgesics, Non-Narcotic; Animals; Bile; Catalase; Ch

2002
Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity.
    Toxicology and applied pharmacology, 1994, Volume: 129, Issue:2

    Topics: Acetaminophen; Analysis of Variance; Animals; Blotting, Western; Carrier Proteins; Clofibrate; Cytoc

1994
Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure.
    American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:4

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Carnitine O-Palmitoyltransferase; Clofibrate; Cre

2000
Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:2

    Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Chemical and Drug Induced Liver Injury; Cl

2000
Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats.
    Atherosclerosis, 1978, Volume: 29, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Clof

1978
[Role of magnesium, potassium, antikaliuretic agents and hypocholesteremic agents in cardiac lesion development in rats fed a thrombogenic diet and Na 2 HPO 4 ].
    Pathologie-biologie, 1972, Volume: 20, Issue:19

    Topics: Animals; Anticholesteremic Agents; Clofibrate; Diet, Atherogenic; Diuretics; Estrogens, Conjugated (

1972
Protection against epinephrine induced myocardial necrosis with clofibrate.
    American heart journal, 1973, Volume: 86, Issue:6

    Topics: Animals; Cardiomyopathies; Clofibrate; Dogs; Drug Antagonism; Epinephrine; Myocardium; Necrosis; Pla

1973
[Multiple aseptic bone necrosis in hyperlipidaemia, hyperuricaemia, and latent diabetes mellitus (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Jul-19, Volume: 99, Issue:29

    Topics: Adult; Allopurinol; Bone Diseases; Clofibrate; Diet Therapy; Dietary Carbohydrates; Femur Head Necro

1974