Compounds > clofibrate
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clofibrate and Muscular Diseases

clofibrate has been researched along with Muscular Diseases in 33 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"Clofibrate has been considered to be a relatively safe antidiuretic in the treatment of diabetes insipidus."7.66Clofibrate-induced myopathy in patients with diabetes insipidus. ( Chihara, K; Fujita, T; Matsukura, S; Matsumoto, J; Yoshimoto, Y, 1980)
"Acute inflammatory muscular syndromes secondary to clofibrate therapy are rare."3.67[Atypical muscular syndrome with myolysis during long-term treatment with fibrates]. ( Brechenmacher, C; Chauvin, M; Zupan, M, 1988)
"Clofibrate has been considered to be a relatively safe antidiuretic in the treatment of diabetes insipidus."3.66Clofibrate-induced myopathy in patients with diabetes insipidus. ( Chihara, K; Fujita, T; Matsukura, S; Matsumoto, J; Yoshimoto, Y, 1980)
"Severe cases of rhabdomyolysis are rarer, but may have a significant mortality."2.41Myopathy and rhabdomyolysis with lipid-lowering drugs. ( Hodel, C, 2002)
"Clofibrate has particular dangers in patients with uraemia or hypoproteinaemia, and we recommend that it be used with great caution in patients with renal disease."1.26Clofibrate-induced complications in renal disease: a case report. ( Gregory, MC; Pokroy, N; Ress, S, 1977)
" If such therapy is contemplated it must be cautiously instituted at low dosage and the patient monitored by regular assessment of serum C."1.25Clofibrate-induced muscle damage in patients with chronic renal failure. ( Alvarez-Ude, F; Kerr, DN; Pierides, AM, 1975)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199028 (84.85)18.7374
1990's2 (6.06)18.2507
2000's3 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okada, M1
Inoue, Y1
Ube, M1
Sano, F1
Ikeda, I1
Sugimoto, J1
Takagi, S1
Rimon, D1
Ludatscher, R1
Cohen, L1
Schneider, J2
Heidemann, H1
Bock, KD1
Wójcicki, J1
Matsukura, S1
Matsumoto, J1
Chihara, K1
Yoshimoto, Y1
Fujita, T1
Mühlfellner, G1
Kaffarnik, H1
Kumamoto, T1
Hodel, C1
Pierides, AM1
Alvarez-Ude, F1
Kerr, DN1
Rumpf, KW2
Albers, R1
Scheler, F2
Pokroy, N1
Ress, S1
Gregory, MC1
Abourizk, N1
Khalil, BA1
Bahuth, N1
Afifi, AK1
Bojs, G1
Fahlén, M1
Lapidus, L1
Cario, WR1
Hoffmann, J1
Hübschmann, K1
Kunze, D1
Regling, G1
Colombo, L1
Monarca, A1
Goldberg, D1
Zanetta, R1
Kijima, Y2
Makise, J1
Sasaoka, T2
Kanayama, M2
Kubota, S2
Smals, AG1
Beex, LV1
Kloppenborg, PW1
Teräväinen, H1
Larsen, A1
Hillbom, M1
Quellhrost, E1
Magarian, GJ1
Lucas, LM1
Colley, C1
Erkul, I1
Yavuz, H1
Ozel, A1
Chauvin, M1
Zupan, M1
Brechenmacher, C1
Rush, P1
Baron, M1
Kapusta, M1
Bardosi, A1
Scheidt, P1
Goebel, HH1
Bridgman, JF1
Rosen, SM1
Thorp, JM1
Denizot, M2
Fabre, J2
Pometta, D1
Wildi, E2
Micheli, H1
Berthoud, S1
Kra, SJ1
Katsilambros, N1
Braaten, J1
Ferguson, BD1
Bradley, RF1
Sekowski, I1
Samuel, P1
Smith, AF1
Macfie, WG1
Oliver, MF1

Reviews

4 reviews available for clofibrate and Muscular Diseases

ArticleYear
[Necrotizing myopathies].
    Ryoikibetsu shokogun shirizu, 2001, Issue:36

    Topics: Acute Disease; Aminocaproic Acid; Anti-Inflammatory Agents; Clofibrate; Diagnosis, Differential; Hum

2001
Myopathy and rhabdomyolysis with lipid-lowering drugs.
    Toxicology letters, 2002, Mar-10, Volume: 128, Issue:1-3

    Topics: Animals; Clofibrate; Female; Humans; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Muscular D

2002
Gemfibrozil-induced myopathy.
    Archives of internal medicine, 1991, Volume: 151, Issue:9

    Topics: Clofibrate; Drug Therapy, Combination; Gemfibrozil; Humans; Hypertriglyceridemia; Lovastatin; Male;

1991
Clofibrate myopathy: a case report and a review of the literature.
    Seminars in arthritis and rheumatism, 1986, Volume: 15, Issue:3

    Topics: Aged; Blood Sedimentation; Clofibrate; Creatine Kinase; Electromyography; Humans; Isoenzymes; Male;

1986

Trials

1 trial available for clofibrate and Muscular Diseases

ArticleYear
Clofibrate, serum enzymes, and muscle pain.
    British medical journal, 1970, Apr-11, Volume: 2, Issue:5701

    Topics: Adult; Alkaline Phosphatase; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Clo

1970

Other Studies

28 other studies available for clofibrate and Muscular Diseases

ArticleYear
Skeletal muscle susceptibility to clofibrate induction of lesions in rats.
    Toxicologic pathology, 2007, Volume: 35, Issue:4

    Topics: Animals; Clofibrate; Diaphragm; Female; Hypolipidemic Agents; Microscopy, Electron; Mitochondria, Mu

2007
Clofibrate-induced muscular syndrome. Case report with ultrastructural findings and review of the literature.
    Israel journal of medical sciences, 1984, Volume: 20, Issue:11

    Topics: Aged; Clofibrate; Humans; Male; Muscles; Muscular Atrophy; Muscular Diseases; Syndrome

1984
Clinical importance of clofibrate induced increase of creatine kinase catalytic activity concentration in serum.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1981, Volume: 19, Issue:8

    Topics: Clofibrate; Creatine Kinase; Humans; Hyperlipidemias; Male; Middle Aged; Muscular Diseases

1981
[Rhabdomyolysis with acute renal failure due to bezafibrate].
    Klinische Wochenschrift, 1981, Apr-15, Volume: 59, Issue:8

    Topics: Acute Kidney Injury; Bezafibrate; Clofibrate; Clofibric Acid; Humans; Male; Middle Aged; Muscular Di

1981
[Current data on adverse effects of clofibrate].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Jan-07, Volume: 35, Issue:1

    Topics: Biliary Tract Diseases; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Clofibrate;

1980
Clofibrate-induced myopathy in patients with diabetes insipidus.
    Endocrinologia japonica, 1980, Volume: 27, Issue:3

    Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Clofibrate; Creatine Kinase; Diabetes

1980
Creatinekinase in hyperlipoproteinemic patients treated with clofibrate.
    Artery, 1980, Volume: 8, Issue:2

    Topics: Clofibrate; Creatine Kinase; Female; Humans; Hyperlipoproteinemias; Male; Middle Aged; Muscular Dise

1980
Clofibrate-induced muscle damage in patients with chronic renal failure.
    Lancet (London, England), 1975, Dec-27, Volume: 2, Issue:7948

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Butyrates; Cholesterol; Clofibrate; Creati

1975
Letter: Clofibrate-induced myopathy syndrome.
    Lancet (London, England), 1976, Jan-31, Volume: 1, Issue:7953

    Topics: Adult; Clofibrate; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hypothyroidism; Kidney

1976
Clofibrate-induced complications in renal disease: a case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Nov-05, Volume: 52, Issue:20

    Topics: Adult; Clofibrate; Humans; Male; Muscular Diseases; Nephrotic Syndrome; Peripheral Nervous System Di

1977
Clofibrate-induced muscular syndrome. Report of a case with clinical, electromyographic and pathologic observations.
    Journal of the neurological sciences, 1979, Volume: 42, Issue:1

    Topics: Adult; Capillaries; Clofibrate; Creatine Kinase; Diabetes Insipidus; Electromyography; Female; Human

1979
[Clofibrate-induced muscle problems].
    Lakartidningen, 1979, Jul-25, Volume: 76, Issue:30-31

    Topics: Adult; Aged; Clofibrate; Female; Humans; Male; Middle Aged; Muscular Diseases

1979
Myopathy induced by clofibrate treatment in normolipaemic patients.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1979, Volume: 20, Issue:1

    Topics: Child; Clofibrate; Creatine Kinase; Diabetes Insipidus; Female; Humans; Injections, Intravenous; Lip

1979
[Tolerability and side-effects of bis-(hydroxy-2-ethylthio)-1,10-decane (BS 530) as compared with clofibrate in the therapy of hyperlipemia].
    La Clinica terapeutica, 1979, Oct-31, Volume: 91, Issue:2

    Topics: Clofibrate; Fatty Alcohols; Gastrointestinal Diseases; Headache; Humans; Hyperlipidemias; Hyperlipop

1979
[The adverse actions of clofibrate in chronic hemodialysis patients--acute muscular syndrome and others (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:9

    Topics: Acute Disease; Adult; Clofibrate; Female; Humans; Male; Middle Aged; Muscular Diseases; Renal Dialys

1978
Untoward effects of clofibrate in hemodialyzed patients.
    The New England journal of medicine, 1977, Mar-03, Volume: 296, Issue:9

    Topics: Clofibrate; Humans; Hyperlipidemias; Muscular Diseases; Renal Dialysis; Uremia

1977
Clofibrate-induced muscle damage with myoglobinuria and cardiomyopathy.
    The New England journal of medicine, 1977, Apr-21, Volume: 296, Issue:16

    Topics: Adolescent; Cardiomyopathies; Clofibrate; Diabetes Insipidus; Humans; Male; Muscular Diseases; Myogl

1977
Clofibrate-induced myopathy in the rat.
    Acta neuropathologica, 1977, Aug-16, Volume: 39, Issue:2

    Topics: Animals; Clofibrate; Female; Microscopy, Electron; Muscles; Muscular Diseases; Rats; Time Factors

1977
[Diabetic nephropathy, hypothyroidism and colfibrate-induced myopathy (author's transl)].
    Medizinische Klinik, 1976, Nov-12, Volume: 71, Issue:46

    Topics: Adult; Clofibrate; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabet

1976
Clofibrate treatment of neonatal jaundice.
    Pediatrics, 1991, Volume: 88, Issue:6

    Topics: Animals; Clofibrate; Humans; Infant, Newborn; Jaundice, Neonatal; Muscular Diseases; Rats

1991
[Atypical muscular syndrome with myolysis during long-term treatment with fibrates].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81, Issue:7

    Topics: Clofibrate; Creatine Kinase; Fructose-Bisphosphate Aldolase; Humans; Male; Middle Aged; Muscular Dis

1988
Mitochondrial myopathy--a result of clofibrate/etofibrate treatment? Case report.
    Acta neuropathologica, 1985, Volume: 68, Issue:2

    Topics: Aged; Clofibrate; Clofibric Acid; Humans; Hypolipidemic Agents; Kearns-Sayre Syndrome; Male; Microsc

1985
Complications during clofibrate treatment of nephrotic-syndrome hyperlipoproteinaemia.
    Lancet (London, England), 1972, Sep-09, Volume: 2, Issue:7776

    Topics: Adult; Binding Sites; Blood Protein Disorders; Clofibrate; Female; Fructose-Bisphosphate Aldolase; H

1972
Clofibrate, nephrotic syndrome, and histological changes in muscle.
    Lancet (London, England), 1973, Jun-09, Volume: 1, Issue:7815

    Topics: Adult; Clofibrate; Humans; Male; Muscles; Muscular Diseases; Nephrotic Syndrome

1973
[Hypolipemic property and myotoxic action of clofibrate in a case of nephrotic syndrome].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Jun-05, Volume: 62, Issue:23

    Topics: Adult; Arteriosclerosis; Cholesterol; Clofibrate; Glomerulonephritis; Humans; Hyperlipidemias; Male;

1973
Muscle syndrome with clofibrate usage.
    Connecticut medicine, 1974, Volume: 38, Issue:7

    Topics: Clofibrate; Electromyography; Female; Humans; Middle Aged; Muscular Diseases

1974
Muscular syndrome after clofibrate.
    The New England journal of medicine, 1972, May-18, Volume: 286, Issue:20

    Topics: Adult; Clofibrate; Female; Humans; Muscular Diseases

1972
Clofibrate-induced acute muscular syndrome.
    The American journal of cardiology, 1972, Volume: 30, Issue:5

    Topics: Acute Disease; Aspartate Aminotransferases; Clofibrate; Creatine Kinase; Female; Humans; Male; Middl

1972