Page last updated: 2024-10-25

clofibrate and Metabolic Syndrome

clofibrate has been researched along with Metabolic Syndrome in 6 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"Treatment with clofibrate is also associated with a decrease in ANP and ANPr expression."5.91PPAR Alpha Activation by Clofibrate Alleviates Ischemia/Reperfusion Injury in Metabolic Syndrome Rats by Decreasing Cardiac Inflammation and Remodeling and by Regulating the Atrial Natriuretic Peptide Compensatory Response. ( Cano-Martínez, A; Castrejón-Téllez, V; Díaz-Díaz, E; Ibarra-Lara, L; Osorio-Yáñez, C; Pavón, N; Rubio-Ruíz, ME; Sánchez-Aguilar, M; Soria-Castro, E, 2023)
"Identification and treatment of the metabolic syndrome is of enormous public health importance because it is associated with a marked elevation in coronary heart disease risk and affects nearly 25% of adults in the United States."2.42Fibrates for treatment of the metabolic syndrome. ( Maki, KC, 2004)
"Metabolic syndrome is associated with increased cardiovascular risk."2.41[Fibrate influence on lipids and insulin resistance in patients with metabolic syndrome]. ( Idzior-Waluś, B, 2001)
"Treatment with clofibrate is also associated with a decrease in ANP and ANPr expression."1.91PPAR Alpha Activation by Clofibrate Alleviates Ischemia/Reperfusion Injury in Metabolic Syndrome Rats by Decreasing Cardiac Inflammation and Remodeling and by Regulating the Atrial Natriuretic Peptide Compensatory Response. ( Cano-Martínez, A; Castrejón-Téllez, V; Díaz-Díaz, E; Ibarra-Lara, L; Osorio-Yáñez, C; Pavón, N; Rubio-Ruíz, ME; Sánchez-Aguilar, M; Soria-Castro, E, 2023)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Pirat, C1
Farce, A1
Lebègue, N1
Renault, N1
Furman, C1
Millet, R1
Yous, S1
Speca, S1
Berthelot, P1
Desreumaux, P1
Chavatte, P1
Sánchez-Aguilar, M1
Ibarra-Lara, L1
Cano-Martínez, A1
Soria-Castro, E1
Castrejón-Téllez, V1
Pavón, N1
Osorio-Yáñez, C1
Díaz-Díaz, E1
Rubio-Ruíz, ME1
Sugatani, J1
Osabe, M1
Wada, T1
Yamakawa, K1
Yamazaki, Y1
Takahashi, T1
Ikari, A1
Miwa, M1
Maki, KC1
Iwasaki, Y1
Takayasu, S1
Nishiyama, M1
Tsugita, M1
Taguchi, T1
Asai, M1
Yoshida, M1
Kambayashi, M1
Hashimoto, K1
Idzior-Waluś, B1

Reviews

3 reviews available for clofibrate and Metabolic Syndrome

ArticleYear
Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.
    Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

    Topics: Animals; Humans; Ligands; Metabolic Syndrome; Models, Molecular; Molecular Targeted Therapy; Peroxis

2012
Fibrates for treatment of the metabolic syndrome.
    Current atherosclerosis reports, 2004, Volume: 6, Issue:1

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Clofibrate; Fenofibrate; Gemfibrozil; Humans; Hyp

2004
[Fibrate influence on lipids and insulin resistance in patients with metabolic syndrome].
    Przeglad lekarski, 2001, Volume: 58, Issue:10

    Topics: Cardiovascular Diseases; Clofibrate; Fenofibrate; Hemostasis; Humans; Hyperinsulinism; Hyperlipidemi

2001

Other Studies

3 other studies available for clofibrate and Metabolic Syndrome

ArticleYear
PPAR Alpha Activation by Clofibrate Alleviates Ischemia/Reperfusion Injury in Metabolic Syndrome Rats by Decreasing Cardiac Inflammation and Remodeling and by Regulating the Atrial Natriuretic Peptide Compensatory Response.
    International journal of molecular sciences, 2023, Mar-10, Volume: 24, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Atrial Natriuretic Factor; Clofibrate; Inflammation; Ischemia; Metabo

2023
Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet.
    European journal of nutrition, 2008, Volume: 47, Issue:4

    Topics: Animals; Biomarkers; Blood Chemical Analysis; Blood Glucose; Clofibrate; Dietary Fats; Dietary Sucro

2008
Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11beta-hydroxysteroid dehydrogenase type 1) gene.
    Molecular and cellular endocrinology, 2008, Mar-26, Volume: 285, Issue:1-2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Anticholesteremic Agents; Base Sequence; Cell

2008