clofibrate has been researched along with Jaundice, Neonatal in 16 studies
angiokapsul: contains clofibrate & insoitolnicotinate
Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A single dose of 50 mg/kg clofibrate in treatment of neonatal hyperbilirubinemia is effective, safe and cost effective in view of reducing hospital stay days." | 2.77 | Single dose of 50 mg/kg clofibrate in jaundice of healthy term neonates: randomised clinical trial of efficacy and safety. ( Fallah, R; Islami, Z; Lotfi, SR, 2012) |
| "Clofibrate is an effective adjunctive drug in neonatal hyperbilirubinemia, which results in decreased TSB level and reduced duration of phototherapy in late pre-term newborns." | 2.74 | The effect of clofibrate with phototherapy in late pre-term newborns with non-hemolytic jaundice. ( Gharehbaghi, MM; Rahbani, ME; Sakha, SH, 2009) |
| "Hyperbilirubinemia is a common problem in newborn infants." | 2.73 | Effect of clofibrate in jaundiced full-term infants:a randomized clinical trial. ( Ahmadpour-Kacho, M; Hajiahmadi, M; Naderi, S; Zahedpasha, Y, 2007) |
| "Treatment with clofibrate also resulted in a shorter duration of jaundice and a decreased use of phototherapy (P < 0." | 2.71 | Effect of clofibrate in jaundiced term newborns. ( Farhat, ASh; Iranpour, R; Mohammadzadeh, A, 2005) |
| " Further studies will allow to define the exact dosage according to gestational age." | 2.66 | [Preventive treatment of jaundice in premature newborn infants with clofibrate. Double-blind controlled therapeutic trial]. ( Benattar, C; Dehan, M; Delaporte, B; Gabilan, JC; Gerbet, D; Leluc, R; Lindenbaum, A; Magny, JF, 1985) |
| "Clofibrate treatment also resulted in a shorter duration of jaundice and a restricted use of phototherapy." | 2.65 | [Clofibrate for the treatment of hyperbilirubinemia in neonates born at term: a double blind controlled study (author's transl)]. ( Benattar, C; Dehan, M; Foliot, A; Gabilan, JC; Hernandorena, X; Janaud, JC; Leluc, R; Lindenbaum, A; Vial, M, 1981) |
| "Clofibrate is a better enhancer of glucuronosyl transferase induction than phenobarbital and causes 100% increase of hepatic bilirubin clearance within 6 hours." | 1.30 | [Pharmacologic treatment of neonatal jaundice. A new approach]. ( Gabilan, JC, 1998) |
| "Clofibrate (CFB) has been proposed to increase elimination of bilirubin in neonates with hyperbilirubinemia." | 1.29 | [Pharmacokinetics of clofibrate in jaundiced newborn infants at term]. ( Bourget, P; Broise, I; Gabilan, JC; Quinquis-Desmaris, V, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chawla, D | 1 |
| Zahedpasha, Y | 2 |
| Ahmadpour-Kacho, M | 2 |
| Hajiahmadi, M | 2 |
| Naderi, S | 2 |
| Kamali, AA | 1 |
| Sakha, SH | 1 |
| Gharehbaghi, MM | 1 |
| Rahbani, ME | 1 |
| Fallah, R | 1 |
| Islami, Z | 1 |
| Lotfi, SR | 1 |
| Dennery, PA | 1 |
| Mohammadzadeh, A | 1 |
| Farhat, ASh | 1 |
| Iranpour, R | 1 |
| Wazir, S | 1 |
| Angiti, RR | 1 |
| Kumar, P | 1 |
| Barré, J | 1 |
| Houin, G | 1 |
| Shastri, RA | 1 |
| Benattar, C | 4 |
| Lindenbaum, A | 4 |
| Tillement, JP | 1 |
| Hernandorena, X | 1 |
| Vial, M | 1 |
| Janaud, JC | 1 |
| Dehan, M | 2 |
| Foliot, A | 1 |
| Leluc, R | 2 |
| Gabilan, JC | 6 |
| Bourget, P | 1 |
| Broise, I | 1 |
| Quinquis-Desmaris, V | 1 |
| Erkul, I | 1 |
| Yavuz, H | 1 |
| Ozel, A | 1 |
| Delaporte, B | 1 |
| Magny, JF | 1 |
| Gerbet, D | 1 |
2 reviews available for clofibrate and Jaundice, Neonatal
| Article | Year |
|---|---|
Pharmacological interventions for the treatment of neonatal jaundice.
Topics: Agar; Bilirubin; Charcoal; Clofibrate; Drugs, Chinese Herbal; Heme; Humans; Infant, Newborn; Jaundic | 2002 |
[Pharmacologic treatment of neonatal jaundice].
Topics: Clofibrate; Humans; Infant, Newborn; Jaundice, Neonatal; Metalloporphyrins; Phenazines; Phenobarbita | 1991 |
7 trials available for clofibrate and Jaundice, Neonatal
| Article | Year |
|---|---|
Efficacy of clofibrate on severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency (a randomized clinical trial).
Topics: Bilirubin; Clofibrate; Combined Modality Therapy; Female; Glucosephosphate Dehydrogenase Deficiency; | 2008 |
The effect of clofibrate with phototherapy in late pre-term newborns with non-hemolytic jaundice.
Topics: Bilirubin; Clofibrate; Combined Modality Therapy; Double-Blind Method; Female; Humans; Hyperbilirubi | 2009 |
Single dose of 50 mg/kg clofibrate in jaundice of healthy term neonates: randomised clinical trial of efficacy and safety.
Topics: Clofibrate; Female; Humans; Infant, Newborn; Jaundice, Neonatal; Male; Single-Blind Method | 2012 |
Effect of clofibrate in jaundiced term newborns.
Topics: Bilirubin; Clofibrate; Combined Modality Therapy; Female; Humans; Infant, Newborn; Jaundice, Neonata | 2005 |
Effect of clofibrate in jaundiced full-term infants:a randomized clinical trial.
Topics: Administration, Oral; Bilirubin; Clofibrate; Combined Modality Therapy; Female; Humans; Hypolipidemi | 2007 |
[Clofibrate for the treatment of hyperbilirubinemia in neonates born at term: a double blind controlled study (author's transl)].
Topics: ABO Blood-Group System; Blood Group Incompatibility; Clinical Trials as Topic; Clofibrate; Double-Bl | 1981 |
[Preventive treatment of jaundice in premature newborn infants with clofibrate. Double-blind controlled therapeutic trial].
Topics: Bilirubin; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Female; Gestational Age; Human | 1985 |
7 other studies available for clofibrate and Jaundice, Neonatal
| Article | Year |
|---|---|
Clofibrate in Neonatal Hyperbilirubinemia.
Topics: Clofibrate; Humans; Hyperbilirubinemia, Neonatal; Infant, Newborn; Jaundice, Neonatal | 2017 |
Effect of clofibrate in jaundiced term neonates.
Topics: Cholagogues and Choleretics; Clofibrate; Humans; Infant, Newborn; Jaundice, Neonatal; Phototherapy; | 2006 |
Effect of hyperbilirubinaemia on the plasma protein binding of chlorophenoxyisobutyric acid in neonates.
Topics: Bilirubin; Blood Proteins; Clofibrate; Clofibric Acid; Humans; Infant, Newborn; Jaundice, Neonatal; | 1984 |
[Pharmacokinetics of clofibrate in jaundiced newborn infants at term].
Topics: Anticholesteremic Agents; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Humans; | 1995 |
[Pharmacologic treatment of neonatal jaundice. A new approach].
Topics: Clofibrate; Combined Modality Therapy; Enzyme Inhibitors; Female; Humans; Infant, Newborn; Jaundice, | 1998 |
Clofibrate treatment of neonatal jaundice.
Topics: Animals; Clofibrate; Humans; Infant, Newborn; Jaundice, Neonatal; Muscular Diseases; Rats | 1991 |
Clofibrate treatment of neonatal jaundice.
Topics: Clinical Trials as Topic; Clofibrate; France; Humans; Infant, Newborn; Jaundice, Neonatal | 1990 |