clofibrate has been researched along with Hypertrophy in 7 studies
angiokapsul: contains clofibrate & insoitolnicotinate
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study analyzed the effects of the chronic administration of clofibrate, a peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist, on the development and established hemodynamic, morphologic, metabolic, and renal manifestations of hyperthyroidism in rats." | 7.74 | Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats. ( Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F, 2008) |
| "By analysis of the data from the Toxicogenomics Database (TG-GATEs), histidine decarboxylase gene (Hdc) was identified as largely and commonly upregulated by three fibrates, clofibrate, fenofibrate, and WY-14,643, which are known to induce hepatocellular hypertrophy and proliferation via stimulation of peroxisome proliferator-activated receptor α (PPARα) in rodents." | 3.96 | Peroxisome proliferator-activated receptor α agonist-induced histidine decarboxylase gene expression in the rat and mouse liver. ( Amagase, Y; Mizukawa, Y; Urushidani, T, 2020) |
| "This study analyzed the effects of the chronic administration of clofibrate, a peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist, on the development and established hemodynamic, morphologic, metabolic, and renal manifestations of hyperthyroidism in rats." | 3.74 | Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats. ( Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Amagase, Y | 1 |
| Mizukawa, Y | 1 |
| Urushidani, T | 1 |
| Asaoka, Y | 1 |
| Togashi, Y | 1 |
| Mutsuga, M | 1 |
| Imura, N | 1 |
| Miyoshi, T | 1 |
| Miyamoto, Y | 1 |
| Rodríguez-Gómez, I | 1 |
| Cruz, A | 1 |
| Moreno, JM | 1 |
| Soler, A | 1 |
| Osuna, A | 1 |
| Vargas, F | 1 |
| Shoda, T | 1 |
| Mitsumori, K | 1 |
| Onodera, H | 1 |
| Toyoda, K | 1 |
| Uneyama, C | 1 |
| Imazawa, T | 1 |
| Hirose, M | 1 |
| Tomarelli, RM | 1 |
| Bauman, LM | 1 |
| Savini, S | 1 |
| Kolde, G | 1 |
| Roessner, A | 1 |
| Themann, H | 1 |
| Martin, E | 1 |
| Feldmann, G | 1 |
7 other studies available for clofibrate and Hypertrophy
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor α agonist-induced histidine decarboxylase gene expression in the rat and mouse liver.
Topics: Animals; Cell Proliferation; Cells, Cultured; Clofibrate; Databases, Genetic; Fenofibrate; Gene Expr | 2020 |
Histopathological image analysis of chemical-induced hepatocellular hypertrophy in mice.
Topics: Animals; Cell Nucleus; Clofibrate; Hepatocytes; Hepatomegaly; Hypertrophy; Image Processing, Compute | 2016 |
Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats.
Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Clofibrate; Disease Models, Animal; Glucuron | 2008 |
The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Clofibrate; Connexins; Cytochrome P-450 En | 1999 |
Effect of Wy-14,643 on cholesterol metabolism in normal and hypercholesterolemic rats.
Topics: Animals; Cholesterol; Clofibrate; Feces; Hypercholesterolemia; Hypertrophy; Hypolipidemic Agents; Li | 1978 |
Effects of clofibrate (alpha-p-chlorophenoxyisobutyryl-ethyl-ester) on male rat liver.
Topics: Animals; Catalase; Clofibrate; Endoplasmic Reticulum; Hypertrophy; Liver; Male; Microscopy, Electron | 1976 |
[Histological and ultrastuctural study of the rat liver following subacute administration of a new hypolipemic agent, bis-(hydroxy-ethyl-thio) 1-10 decane].
Topics: Animals; Clofibrate; Endoplasmic Reticulum; Hypertrophy; Hypolipidemic Agents; Liver; Microscopy, El | 1974 |