clofibrate has been researched along with Hyperplasia in 7 studies
angiokapsul: contains clofibrate & insoitolnicotinate
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We showed previously that the peroxisome proliferators di(2-ethylhexyl)phthalate (DEHP), clofibrate, and 4-chloro-6-(2,3 xylidino)-2-pyrimidinylthio (N-beta-hydroxyl)acetamide (BR931) alter hepatic sex steroid metabolism and receptor expression during induction of hepatic hyperplasia and hepatocellular carcinoma (HCC) in rats." | 3.69 | Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth. ( Brady, EP; Chandar, N; Eagon, PK; Elm, MS; Kelly, RH; Rao, B; Rao, KN; Shinozuka, H, 1997) |
| " It is suggested that the liver lesions of this woman may be related to long-term administration of hypolipidemic drug clofibrate for hypercholesteremia and the lesions could be one of the precursor changes of human hepatocellular carcinoma." | 3.66 | Adenoma with multiple hyperplastic nodules in noncirrhotic liver possibly related to long-term administration of a hypolipidemic drug. ( Mori, H; Sugie, S; Takahashi, M; Tanaka, T, 1982) |
| "Rats treated with clofibrate revealed foci of cellular alteration that were more often basophilic and occurred slightly sooner (wk 42) than those in untreated controls (wk 60)." | 1.27 | Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility. ( Greaves, P; Irisarri, E; Monro, AM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mori, H | 1 |
| Tanaka, T | 1 |
| Sugie, S | 1 |
| Takahashi, M | 1 |
| Rao, KN | 1 |
| Elm, MS | 1 |
| Kelly, RH | 1 |
| Chandar, N | 1 |
| Brady, EP | 1 |
| Rao, B | 1 |
| Shinozuka, H | 1 |
| Eagon, PK | 1 |
| Tsukada, H | 3 |
| Gotoh, M | 1 |
| Mochizuki, Y | 3 |
| Furukawa, K | 1 |
| Itabashi, M | 1 |
| Goto, M | 1 |
| Greaves, P | 1 |
| Irisarri, E | 1 |
| Monro, AM | 1 |
| Bittard, M | 1 |
1 review available for clofibrate and Hyperplasia
| Article | Year |
|---|---|
[Prognosis of primary tumors of the bladder].
Topics: Aged; Alkylating Agents; Amines; Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Clofi | 1985 |
6 other studies available for clofibrate and Hyperplasia
| Article | Year |
|---|---|
Adenoma with multiple hyperplastic nodules in noncirrhotic liver possibly related to long-term administration of a hypolipidemic drug.
Topics: Aged; Carcinoma, Hepatocellular; Clofibrate; Female; Humans; Hypercholesterolemia; Hyperplasia; Hype | 1982 |
Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth.
Topics: Animals; Blotting, Western; Carcinogens; Cell Division; Cholesterol; Clofibrate; Diethylhexyl Phthal | 1997 |
Changes in peroxisomes in preneoplastic liver and hepatoma of mice induced by alpha-benzene hexachloride.
Topics: Animals; Clofibrate; Hexachlorocyclohexane; Hyperplasia; Liver Neoplasms, Experimental; Male; Mice; | 1979 |
Changes in peroxisomes in preneoplastic liver of rats induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Differentiation; Clofibrate; Enzyme Induction; Hy | 1977 |
[Proceedings: Peroxisome in 2-fluorenylacetamide-induced hyperplastic liver nodule cells].
Topics: 2-Acetylaminofluorene; Animals; Clofibrate; Fluorenes; Hyperplasia; Liver Neoplasms; Microbodies; Or | 1975 |
Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility.
Topics: Animals; Body Weight; Clofibrate; Diethylnitrosamine; gamma-Glutamyltransferase; Glucosephosphate De | 1986 |