Page last updated: 2024-10-25

clofibrate and Heart Disease, Ischemic

clofibrate has been researched along with Heart Disease, Ischemic in 6 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Research Excerpts

ExcerptRelevanceReference
"Clofibrate was able to decrease Angiotensin II (AngII), AngII AT1-receptor, whereas Ang-(1-7) and AngII AT2-receptor expression increased."5.38Clofibrate PPARα activation reduces oxidative stress and improves ultrastructure and ventricular hemodynamics in no-flow myocardial ischemia. ( Cervantes-Pérez, LG; Del Valle-Mondragón, L; Hong, E; Ibarra-Lara, L; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC, 2012)
" Male Wistar rats (weighing 300-350 g) were assigned to the following groups: (1) sham, (2) myocardial ischemia vehicle-treated (MI-V), and (3) myocardial ischemia clofibrate-treated."3.81PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System. ( Cervantes-Pérez, LG; del Valle-Mondragón, L; Hong, E; Ibarra-Lara, L; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Aguilar, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC, 2015)
"Clofibrate was able to decrease Angiotensin II (AngII), AngII AT1-receptor, whereas Ang-(1-7) and AngII AT2-receptor expression increased."1.38Clofibrate PPARα activation reduces oxidative stress and improves ultrastructure and ventricular hemodynamics in no-flow myocardial ischemia. ( Cervantes-Pérez, LG; Del Valle-Mondragón, L; Hong, E; Ibarra-Lara, L; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Ibarra-Lara, L3
Sánchez-Aguilar, M2
Del Valle-Mondragón, L3
Soria-Castro, E3
Cervantes-Pérez, LG3
Pastelín-Hernández, G1
Sánchez-Mendoza, A3
Hong, E2
Pérez-Severiano, F2
Torres-Narváez, JC2
Ramírez-Ortega, M2
Pastelín-Hernández, GS2
Fowler, PB1
Heady, JA2
Morris, JN2
Oliver, MF2

Trials

2 trials available for clofibrate and Heart Disease, Ischemic

ArticleYear
WHO clofibrate/cholesterol trial: clarifications.
    Lancet (London, England), 1993, Jan-30, Volume: 341, Issue:8840

    Topics: Cholesterol; Clofibrate; Female; Humans; Male; Myocardial Ischemia; Thyroid Diseases; World Health O

1993
WHO clofibrate/cholesterol trial: clarifications.
    Lancet (London, England), 1992, Dec-05, Volume: 340, Issue:8832

    Topics: Clofibrate; Humans; Hypercholesterolemia; Male; Meta-Analysis as Topic; Myocardial Ischemia; Researc

1992

Other Studies

4 other studies available for clofibrate and Heart Disease, Ischemic

ArticleYear
Clofibrate improves myocardial ischemia-induced damage through regulation of renin-angiotensin system and favours a pro-vasodilator profile in left ventricle.
    Journal of pharmacological sciences, 2020, Volume: 144, Issue:4

    Topics: Angiotensin II; Animals; Clofibrate; Fibrosis; Heart Ventricles; Male; Myocardial Ischemia; Myocardi

2020
PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System.
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:5

    Topics: Angiotensin-Converting Enzyme 2; Animals; Bradykinin; Clofibrate; Disease Models, Animal; Enzyme Act

2015
Clofibrate PPARα activation reduces oxidative stress and improves ultrastructure and ventricular hemodynamics in no-flow myocardial ischemia.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:4

    Topics: Animals; Antioxidants; Catalase; Clofibrate; Disease Models, Animal; Hemodynamics; Lipid Peroxidatio

2012
Ischaemic heart disease and cholesterol ... and mislead on adverse effects.
    BMJ (Clinical research ed.), 1994, Apr-16, Volume: 308, Issue:6935

    Topics: Clinical Trials as Topic; Clofibrate; Humans; Male; Myocardial Ischemia

1994