Page last updated: 2024-10-25

clofibrate and Enlarged Liver

clofibrate has been researched along with Enlarged Liver in 22 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Research Excerpts

ExcerptRelevanceReference
"However, no hepatomegaly was observed in these animals."1.27Factors which may be significant regarding regulation of the clofibrate-dependent induction of hepatic peroxisomal beta-oxidation and hepatomegaly. ( Eliassen, K; Osmundsen, H, 1984)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199016 (72.73)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asaoka, Y1
Togashi, Y1
Mutsuga, M1
Imura, N1
Miyoshi, T1
Miyamoto, Y1
Makino, T1
Kinoshita, J1
Arakawa, S1
Ito, K1
Ando, Y1
Yamoto, T1
Teranishi, M1
Sanbuissho, A1
Nakayama, H1
Nemoto, K3
Tanaka, T1
Ikeda, A1
Ito, S1
Mizukami, M1
Hikida, T1
Gamou, T3
Habano, W2
Ozawa, S3
Inoue, K3
Yoshida, M3
Nishikawa, A3
Degawa, M3
Fujimoto, N1
Youssef, JA1
Bouziane, M1
Badr, MZ1
BEST, MM1
DUNCAN, CH1
AZARNOFF, DL1
TUCKER, DR1
BARR, GA1
Kawashima, Y1
Katoh, H1
Kozuka, H1
Eliassen, K1
Osmundsen, H1
Fort, FL1
Stein, HH1
Langenberg, K1
Lewkowski, JP1
Heyman, IA1
Kesterson, JW1
Berman, JS1
Hiley, CR1
Wilson, AC1
Lazarow, PB1
Shio, H1
Leroy-Houyet, MA1
Schladt, L1
Hartmann, R1
Timms, C1
Strolin-Benedetti, M1
Dostert, P1
Wörner, W1
Oesch, F1
Lake, BG1
Kozlen, SL1
Evans, JG1
Gray, TJ1
Young, PJ1
Gangolli, SD1
Dalton, C1
Hope, WC1
Hope, HR1
Sheppard, H1
Baird, MB1
Zimmerman, JA1
Massie, HR1
Samis, HV1
Rozé, C1
Debray, C1
Vaille, C1
Souchard, M1
Hruban, Z1
Gotoh, M1
Slesers, A1
Chou, SF1
Kritchevsky, D1
Tepper, SA1
Elwood, JC1
Richert, DA1
Westerfeld, WW1
Beckett, RB1
Weiss, R1
Stitzel, RE1
Cenedella, RJ1

Other Studies

22 other studies available for clofibrate and Enlarged Liver

ArticleYear
Histopathological image analysis of chemical-induced hepatocellular hypertrophy in mice.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2016, Volume: 68, Issue:4

    Topics: Animals; Cell Nucleus; Clofibrate; Hepatocytes; Hepatomegaly; Hypertrophy; Image Processing, Compute

2016
Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:6

    Topics: Acyl-CoA Dehydrogenase; Animals; Carnitine O-Palmitoyltransferase; Clofibrate; Dogs; Electrophoresis

2009
Super-induced gene expression of the N-methyl-D-aspartate receptor 2C subunit in chemical-induced hypertrophic liver in rats.
    The Journal of toxicological sciences, 2011, Volume: 36, Issue:5

    Topics: Animals; Clofibrate; Disease Models, Animal; Gene Expression; Hepatomegaly; Liver; Male; Oligonucleo

2011
Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats.
    The Journal of toxicological sciences, 2011, Volume: 36, Issue:5

    Topics: Animals; Cell Cycle Proteins; Clofibrate; Cytochrome P-450 Enzyme System; DNA Damage; Down-Regulatio

2011
Estrogen and androgen receptor status in hepatocellular hypertrophy induced by phenobarbital, clofibrate, and piperonyl butoxide in F344 rats.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:2

    Topics: Animals; Carcinogens; CD36 Antigens; Clofibrate; Estrogen Receptor alpha; Female; Hepatomegaly; Leuk

2012
Age-dependent effects of nongenotoxic hepatocarcinogens on liver apoptosis in vivo.
    Mechanisms of ageing and development, 2003, Volume: 124, Issue:3

    Topics: Aging; Animals; Apoptosis; Carcinogens; Cell Count; Cholesterol; Clofibrate; Hepatocytes; Hepatomega

2003
HYPOLIPEMIA AND HEPATOMEGALY FROM ETHYL CHLOROPHENOXYISOBUTYRATE (CPIB) IN THE RAT.
    The Journal of laboratory and clinical medicine, 1964, Volume: 64

    Topics: Adrenalectomy; Androsterone; Anticholesteremic Agents; Butyrates; Castration; Cholesterol; Clofibrat

1964
STUDIES WITH ETHYL CHLOROPHENOXYISOBUTYRATE (CLOFIBRATE).
    Metabolism: clinical and experimental, 1965, Volume: 14

    Topics: Anticholesteremic Agents; Butyrates; Carbon Dioxide; Cholesterol; Clofibrate; Glycerides; Hepatomega

1965
Differential effects of altered hormonal state on the induction of acyl-CoA hydrolases and peroxisomal beta-oxidation by clofibric acid.
    Biochimica et biophysica acta, 1983, Feb-07, Volume: 750, Issue:2

    Topics: Adrenalectomy; Animals; Clofibrate; Clofibric Acid; Dexamethasone; Diabetes Mellitus, Experimental;

1983
Factors which may be significant regarding regulation of the clofibrate-dependent induction of hepatic peroxisomal beta-oxidation and hepatomegaly.
    Biochemical pharmacology, 1984, Apr-01, Volume: 33, Issue:7

    Topics: Adenosylmethionine Decarboxylase; Adrenalectomy; Animals; Clofibrate; Eflornithine; Hepatomegaly; Hy

1984
Cetaben versus clofibrate: comparison of toxicity and peroxisome proliferation in rats.
    Toxicology, 1983, Volume: 28, Issue:4

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Animals; Body Weight; Catalase; Clofibrate; Female; Hepatomegal

1983
Comparison of the effects of the hypolipidaemic agents ICI53072 and clofibrate with those of phenobarbitone on liver size, blood flow and DNA content in the rat.
    British journal of pharmacology, 1983, Volume: 78, Issue:3

    Topics: Animals; Bile; Cardiac Output; Clofibrate; DNA; Hepatomegaly; Hypolipidemic Agents; Liver; Liver Cir

1983
Specificity in the action of hypolipidemic drugs: increase of peroxisomal beta-oxidation largely dissociated from hepatomegaly and peroxisome proliferation in the rat.
    Journal of lipid research, 1982, Volume: 23, Issue:2

    Topics: Animals; Bezafibrate; Cell Division; Cell Fractionation; Clofibrate; Clofibric Acid; Female; Hepatom

1982
Concomitant induction of cytosolic but not microsomal epoxide hydrolase with peroxisomal beta-oxidation by various hypolipidemic compounds.
    Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3

    Topics: Animals; Aspirin; Clofibrate; Cytosol; Dose-Response Relationship, Drug; Enzyme Induction; Epoxide H

1987
Effect of prolonged administration of clofibric acid and di-(2-ethylhexyl)phthalate on hepatic enzyme activities and lipid peroxidation in the rat.
    Toxicology, 1987, Volume: 44, Issue:2

    Topics: Animals; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Hepatomegaly; Lipid Peroxides; Liver; M

1987
Relationship of serum triglyceride lowering to changes in hepatic composition induced by different classes of drugs.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Cholesterol; Clofibrate; Dactinomycin; DNA; Dose-Response Relationship, Drug; Glycolates; H

1974
Response of liver and kidney catalase to alpha-p-chlorophenoxyisobutyrate (clofibrate) in C57B1/6J male mice of different ages.
    Gerontologia, 1974, Volume: 20, Issue:3

    Topics: Aging; Animals; Catalase; Clofibrate; Hepatomegaly; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; O

1974
[Induced hypercholeresis and excretion of bile salts after treatment with clofibrate].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1972, Jun-19, Volume: 274, Issue:25

    Topics: Animals; Bicarbonates; Bile; Bile Acids and Salts; Bilirubin; Chlorine; Clofibrate; Hepatomegaly; Li

1972
Structure of hepatic microbodies in rats treated with acetylsalicylic acid, clofibrate, and dimethrin.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 30, Issue:1

    Topics: Animals; Aspirin; Benzyl Compounds; Body Weight; Carboxylic Acids; Cholesterol; Chrysanthemum cinera

1974
Effect of 2-acetoamidoethyl (p-chlorophenyl) (m-trifluoromethylphenoxy) acetate (halofenate) on cholesterol oxidation by rat liver mitochondria.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:4

    Topics: Acetamides; Animals; Anticholesteremic Agents; Autoradiography; Carbon Isotopes; Cholesterol; Clofib

1972
A comparison of hypolipidemic drugs in the prevention of an orotic acid fatty liver.
    Biochemical pharmacology, 1972, Apr-15, Volume: 21, Issue:8

    Topics: Animals; Clofibrate; Diet; Electrophoresis; Ethylamines; Fatty Liver; Glucosephosphate Dehydrogenase

1972
Studies on the hepatomegaly caused by the hypolipidemic drugs nafenopin and clofibrate.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:1

    Topics: Aniline Compounds; Animals; Clofibrate; DNA; Drug Interactions; Endoplasmic Reticulum; Hepatomegaly;

1972