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clofibrate and Diabetes Mellitus, Type 2

clofibrate has been researched along with Diabetes Mellitus, Type 2 in 10 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"Clofibrate 1500 mg was administered for 1 month to 15 patients, and 75 g oral glucose tolerance test and insulin tolerance test were carried out before and after 1 month of the treatment."1.27Clofibrate enhances the affinity of insulin receptors in non-insulin dependent diabetes mellitus. ( Kobayashi, M; Koh, H; Murakami, K; Nambu, S; Shigeta, Y, 1984)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henke, BR1
Abramson, J1
Murakami, K1
Nambu, S2
Koh, H1
Kobayashi, M2
Shigeta, Y2
Skrha, J1
Sindelka, G1
Haas, T1
Hilgertová, J1
Justová, V1
Welborn, TA1
Rajecová, E1
Klimes, I1
Seböková, E1
Rychnavská, E1
Pleváková, L1
Linke-Cvrkalová, A1
Langrová, H1
Wang, MY1
Koyama, K1
Shimabukuro, M1
Mangelsdorf, D1
Newgard, CB1
Unger, RH1
Gómez Gómez, M1
Valdivieso Martínez, B1
Jaén Martínez, F1
Hanefeld, M1
Schulze, J1
Fischer, S1
Rössger, G1
Lindner, J1
Groh, G1
Nehring, A1
Capek, R1
Hirata, Y1
Omori, Y1
Sakamoto, N1
Baba, S1

Reviews

2 reviews available for clofibrate and Diabetes Mellitus, Type 2

ArticleYear
Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes.
    Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17

    Topics: Animals; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Models, Molecular; M

2004
Dyslipidaemia in non-insulin dependent diabetes: the need for a clinical intervention trial.
    Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:1

    Topics: Cholesterol, HDL; Clinical Trials as Topic; Clofibrate; Coronary Disease; Diabetes Mellitus, Type 2;

1994

Trials

2 trials available for clofibrate and Diabetes Mellitus, Type 2

ArticleYear
[Intensive basic therapy decreases the need for drug treatment and improves glucose control: an important result of the diabetes intervention study].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1988, Dec-15, Volume: 43, Issue:24

    Topics: Clinical Trials as Topic; Clofibrate; Clofibric Acid; Combined Modality Therapy; Diabetes Mellitus,

1988
Improvement of glucose tolerance in NIDDM by clofibrate. Randomized double-blind study.
    Diabetes care, 1988, Volume: 11, Issue:6

    Topics: Blood Glucose; Clinical Trials as Topic; Clofibrate; Diabetes Mellitus, Type 2; Double-Blind Method;

1988

Other Studies

6 other studies available for clofibrate and Diabetes Mellitus, Type 2

ArticleYear
Comments on the MRC/BHF Heart Protection Study.
    Lancet (London, England), 2003, Aug-30, Volume: 362, Issue:9385

    Topics: Adult; Antihypertensive Agents; Cholesterol; Clofibrate; Coronary Disease; Cost-Benefit Analysis; Di

2003
Clofibrate enhances the affinity of insulin receptors in non-insulin dependent diabetes mellitus.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:1

    Topics: Blood Glucose; Clofibrate; Diabetes Mellitus, Type 2; Erythrocytes; Female; Glucose Tolerance Test;

1984
[Relation between hypertriacylglycerolemia and the action of insulin in type 2 diabetes mellitus].
    Casopis lekaru ceskych, 1994, Aug-22, Volume: 133, Issue:16

    Topics: Adult; Aged; Clofibrate; Diabetes Mellitus, Type 2; Female; Fenofibrate; Humans; Hypertriglyceridemi

1994
[Etofylline clofibrate in the treatment of diabetic dyslipidemia: results of a 6-month period of therapy].
    Vnitrni lekarstvi, 1995, Volume: 41, Issue:10

    Topics: Clofibrate; Diabetes Mellitus, Type 2; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoprotei

1995
Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-29, Volume: 95, Issue:20

    Topics: Animals; Base Sequence; Carrier Proteins; Clofibrate; Diabetes Mellitus, Type 2; DNA Primers; DNA-Bi

1998
[Drug interactions in geriatrics. Apropos a case].
    Atencion primaria, 1989, Volume: 6, Issue:5

    Topics: Aged; Clofibrate; Diabetes Mellitus, Type 2; Drug Synergism; Glyburide; Humans; Hypoglycemia; Male

1989