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clofibrate and Cocarcinogenesis

clofibrate has been researched along with Cocarcinogenesis in 7 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Cocarcinogenesis: The combination of two or more different factors in the production of cancer.

Research Excerpts

ExcerptRelevanceReference
"Incidences of hepatocellular carcinomas were 75% (9/12, P < 0."1.30Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation. ( Hagiwara, A; Hasegawa, R; Imaida, K; Ito, N; Sano, M; Shirai, T; Tamano, S, 1999)
"Ciprofibrate treatment did not increase the number or volume of altered hepatic foci (putative preneoplastic lesions)."1.28Lack of initiating activity of the peroxisome proliferator ciprofibrate in two-stage hepatocarcinogenesis. ( Clark, TD; Glauert, HP, 1989)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mochizuki, Y2
Furukawa, K2
Sawada, N2
Sano, M1
Hagiwara, A1
Tamano, S1
Hasegawa, R1
Imaida, K1
Ito, N1
Shirai, T1
Orellana, A1
Hidalgo, PC1
Morales, MN1
Mezzano, D1
Bronfman, M1
Glauert, HP1
Clark, TD1
Fukami, MH1
Eikhom, TS1
Ekanger, R1
Flatmark, T1
Nilsson, A1
Kurokawa, Y1
Takamura, N1
Matushima, Y1
Imazawa, T1
Hayashi, Y1

Other Studies

7 other studies available for clofibrate and Cocarcinogenesis

ArticleYear
Effect of simultaneous administration of clofibrate with diethylnitrosamine on hepatic tumorigenesis in the rat.
    Cancer letters, 1983, Volume: 19, Issue:1

    Topics: Animals; Clofibrate; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver N

1983
Effects of various concentrations of ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat.
    Carcinogenesis, 1982, Volume: 3, Issue:9

    Topics: Animals; Body Weight; Clofibrate; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship,

1982
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.
    The Journal of toxicological sciences, 1999, Volume: 24, Issue:3

    Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinoma, Hepatocellular; Clofibrate; Cocarcinogenesis;

1999
Palmitoyl-CoA and the acyl-CoA thioester of the carcinogenic peroxisome-proliferator ciprofibrate potentiate diacylglycerol-activated protein kinase C by decreasing the phosphatidylserine requirement of the enzyme.
    European journal of biochemistry, 1990, May-31, Volume: 190, Issue:1

    Topics: Acyl Coenzyme A; Animals; Blood Platelets; Brain; Calcium; Clofibrate; Clofibric Acid; Cocarcinogene

1990
Lack of initiating activity of the peroxisome proliferator ciprofibrate in two-stage hepatocarcinogenesis.
    Cancer letters, 1989, Volume: 44, Issue:2

    Topics: Animals; Clofibrate; Clofibric Acid; Cocarcinogenesis; Diet; Dose-Response Relationship, Drug; Femal

1989
Relation between induction of ornithine decarboxylase and specific gene expression in rat liver in response to the tumor promoter agent clofibrate.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: Acyl Coenzyme A; Animals; Carcinogens; Clofibrate; Cocarcinogenesis; Cyclic AMP; Enoyl-CoA Hydratase

1986
Promoting effect of peroxisome proliferators in two-stage rat renal tumorigenesis.
    Cancer letters, 1988, Dec-01, Volume: 43, Issue:1-2

    Topics: Animals; Clofibrate; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosamine; Kidney Neoplasms;

1988