Page last updated: 2024-10-25

clofibrate and Cholelithiasis

clofibrate has been researched along with Cholelithiasis in 49 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).

Research Excerpts

ExcerptRelevanceReference
"A patient with primary biliary cirrhosis is reported in whom the administration of clofibrate in a dose of 1 g per day for 2 months resulted in a marked increase in hypercholesterolemia, and endoscopic retrograde cholangiography showed multiple intrahepatic gallstones."7.65Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones. ( Elias, E; Sherlock, S; Summerfield, JA, 1975)
" Major risk factors associated with cholesterol gallstone formation are American Indian ancestry, female sex, obesity, and ingestion of lithogenic drugs, such as estrogen-containing preparations and clofibrate."3.66Who gets gallstones and why. ( Tangedahl, TN, 1979)
"A patient with primary biliary cirrhosis is reported in whom the administration of clofibrate in a dose of 1 g per day for 2 months resulted in a marked increase in hypercholesterolemia, and endoscopic retrograde cholangiography showed multiple intrahepatic gallstones."3.65Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones. ( Elias, E; Sherlock, S; Summerfield, JA, 1975)
" Patients receiving clofibrate and both estrogen dosage groups had the highest incidence of cholecystitis or cholelithiasis."2.64Gallbladder disease as a side effect of drugs influencing lipid metabolism. Experience in the Coronary Drug Project. ( , 1977)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199045 (91.84)18.7374
1990's4 (8.16)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Loizeau, E1
Hirayama, C1
Kishimoto, Y1
Hüdepohl, JM1
Zielke, R1
Grundy, SM2
Dederer, IuM2
Krylova, NP1
Ustinov, GG2
Paul, R1
Ramesha, CS1
Ganguly, J1
Prokhorov, VI1
Reuter, W2
Fabbrocini, V1
Kawamoto, T3
Kajiyama, G4
Maruhashi, A3
Mizuno, T2
Yamada, K2
Fujiyama, M2
Miyoshi, A3
Chevrel, B1
Takikawa, H1
Yamanaka, M1
Ito, S1
Hasegawa, H1
Nozawa, S1
Ishikawa, H1
Tohyama, C1
Nakazono, K1
Murasawa, A1
Nakano, M1
Onuki, K1
Arakawa, M1
Cooper, J1
Geizerova, H1
Oliver, MF1
Hellström, K1
Einarsson, K1
Vogelberg, KH1
Bennion, LJ1
Dry, J1
Pradalier, A1
de Gennes, JL1
Tangedahl, TN1
Schwandt, P1
Garcia-Romero, E1
Lopez-Cantarero, M1
Arcelus, IM1
Bateson, MC1
Maclean, D1
Ross, PE1
Bouchier, IA1
Palmer, RH1
Paumgartner, G1
Standaert, L1
Morrissey, KP1
Summerfield, JA1
Elias, E1
Sherlock, S1
Modi, RP1
Jain, TC1
Baid, JC1
Maheshwari, M1
Bell, GD1
McNicol, GP1
Davies, JA1
Keclík, M1
Saito, T1
Nakamura, N1
Takahashi, W1
Kobayashi, N1
Pertsemlidis, D1
Panveliwalla, D1
Ahrens, EH1
Dam, H2
Prange, I1
Sondergaard, E1
Thistle, JL1
Schoenfield, LJ1
Besançon, F2
Marche, C2
Barret, C1
Parrot, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000482]Phase 30 participants Interventional1965-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for clofibrate and Cholelithiasis

ArticleYear
[Effects of alcohol and medication on bile acid metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:7

    Topics: Animals; Bile Acids and Salts; Cholelithiasis; Cholesterol, HDL; Clofibrate; Contraceptives, Oral; C

1984
[Iatrogenic cholelithiasis].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:8

    Topics: Bile; Biliary Tract Surgical Procedures; Cholelithiasis; Cholestyramine Resin; Clofibrate; Diet; Est

1982
On the mechanism of hypocholesterolemic effects of polyunsaturated lipids.
    Advances in lipid research, 1980, Volume: 17

    Topics: Animals; Anticholesteremic Agents; Bile; Bile Acids and Salts; Chemical Phenomena; Chemistry; Cholel

1980
[Nonsurgical endoscopic methods of treatment for residual stones in the bile ducts (a review of the Soviet and foreign literature)].
    Vestnik khirurgii imeni I. I. Grekova, 1980, Volume: 125, Issue:8

    Topics: Bile Duct Diseases; Caprylates; Cholelithiasis; Cholestyramine Resin; Cholic Acids; Clofibrate; Endo

1980
[Diseases of the biliary system in obesity].
    Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53 Suppl

    Topics: Cholelithiasis; Cholesterol; Clofibrate; Diet, Reducing; Female; Gastric Bypass; Humans; Male; Obesi

1995
[Etiology, physiopathology and therapy of drug-induced gallbladder lesions].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1995, Feb-10, Volume: 84, Issue:2

    Topics: Aged; Chenodeoxycholic Acid; Cholelithiasis; Clofibrate; Female; Humans; Hypolipidemic Agents; Middl

1995
Bile acid metabolism in hyperlipoproteinaemia.
    Clinics in gastroenterology, 1977, Volume: 6, Issue:1

    Topics: Bile Acids and Salts; Cholelithiasis; Cholesterol; Cholestyramine Resin; Cholic Acids; Chylomicrons;

1977
[Lipid-lowering drugs. Therapeutics and adverse effects].
    Medizinische Klinik, 1979, Aug-10, Volume: 74, Issue:32-33

    Topics: Arteriosclerosis; Child; Cholelithiasis; Cholestyramine Resin; Clofibrate; Colestipol; Dextrothyroxi

1979
The metabolic disorder in cholesterol gall stone disease.
    Nutrition reviews, 1978, Volume: 36, Issue:2

    Topics: Adult; Cholelithiasis; Cholesterol; Clofibrate; Diabetes Complications; Estrogens; Humans; Insulin;

1978
Risk factors for the development of cholelithiasis in man (second of two parts).
    The New England journal of medicine, 1978, Nov-30, Volume: 299, Issue:22

    Topics: Adolescent; Adult; Age Factors; Anemia, Hemolytic; Bile; Cholelithiasis; Clofibrate; Contraceptives,

1978
[Therapeutics in 1978].
    La Revue du praticien, 1978, Sep-21, Volume: 28, Issue:41

    Topics: Amenorrhea; Anticholesteremic Agents; Artificial Organs; Biliary Tract Diseases; Bromocriptine; Chol

1978
[What is reliable in the internal therapy of the gallstone trouble?].
    Der Internist, 1975, Volume: 16, Issue:12

    Topics: Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Clofibrate; Diet; Dose-Response Relationsh

1975
Current concepts of gallstone formation.
    Major problems in clinical surgery, 1975, Volume: 16

    Topics: Animals; Bile; Bile Acids and Salts; Cholecystectomy; Cholelithiasis; Cholesterol; Cholestyramine Re

1975
Advances in medicine.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Anemia, Macrocytic; Anti-Arrhythmia Agents; Anticoagulants; Azathioprine; Chemical and Drug Induced

1972
Determinants of cholesterol cholelithiasis in man and animals.
    The American journal of medicine, 1971, Volume: 51, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Chickens; Cholelithiasis; Cholesterol; Cholestyramine Resin; Cl

1971

Trials

4 trials available for clofibrate and Cholelithiasis

ArticleYear
Letter: Clofibrate and gallstones.
    Lancet (London, England), 1975, May-10, Volume: 1, Issue:7915

    Topics: Adult; Cholelithiasis; Clofibrate; Coronary Disease; Humans; Male; Middle Aged

1975
Gallbladder disease as a side effect of drugs influencing lipid metabolism. Experience in the Coronary Drug Project.
    The New England journal of medicine, 1977, 05-26, Volume: 296, Issue:21

    Topics: Adult; Age Factors; Anticholesteremic Agents; Body Height; Body Weight; Cholecystitis; Cholelithiasi

1977
A co-operative trial in the primary prevention of ischaemic heart disease using clofibrate. Report from the Committee of Principal Investigators.
    British heart journal, 1978, Volume: 40, Issue:10

    Topics: Adult; Cardiovascular Diseases; Cholelithiasis; Cholesterol; Clinical Trials as Topic; Clofibrate; C

1978
[Real or alleged risks of clofibrate derivatives and certain risks of their prohibition].
    La Nouvelle presse medicale, 1979, Mar-31, Volume: 8, Issue:15

    Topics: Adult; Arteriosclerosis; Cholelithiasis; Clinical Trials as Topic; Clofibrate; Coronary Disease; Eur

1979

Other Studies

30 other studies available for clofibrate and Cholelithiasis

ArticleYear
[Nutritional and medicinal factors in biliary cholesterol lithiasis].
    Revue medicale de la Suisse romande, 1984, Volume: 104, Issue:3

    Topics: Cholelithiasis; Cholesterol, Dietary; Clofibrate; Contraceptives, Oral; Dietary Carbohydrates; Dieta

1984
[Formation and modification of bile lipids].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1983, Nov-30, Volume: 59, Issue:33

    Topics: Animals; Bile; Cholelithiasis; Cholesterol; Clofibrate; Contraceptives, Oral, Hormonal; Diabetes Mel

1983
Mechanism of cholesterol gallstones formation.
    Seminars in liver disease, 1983, Volume: 3, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol

1983
[Clofibrate therapy--the status quo].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Jan-15, Volume: 37, Issue:2

    Topics: Carcinogens; Cholelithiasis; Cholesterol; Clofibrate; Humans; Hyperlipoproteinemias; Lipoproteins, L

1982
[Current treatment with clofibrate or clofibric acid (Regadrin)].
    Zeitschrift fur arztliche Fortbildung, 1982, May-15, Volume: 76, Issue:10

    Topics: Cholelithiasis; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hypercholesterolemia; Hyperlipoprot

1982
[Study of clofibrate. The opinion of Prof. D. Kritchevsky].
    Minerva cardioangiologica, 1980, Volume: 28, Issue:11

    Topics: Adult; Arteriosclerosis; Cholelithiasis; Clofibrate; Coronary Disease; Drug Evaluation; Humans; Hype

1980
The influence of dietary cholesterol on the lithogenesity of bile in rats treated with clofibrate (II).
    Hiroshima journal of medical sciences, 1981, Volume: 30, Issue:2

    Topics: Animals; Bile Acids and Salts; Cholelithiasis; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary

1981
[Chenodeoxycholic acid. Indications in biliary pathology and hyperlipoproteinemias].
    Medecine & chirurgie digestives, 1980, Volume: 9, Issue:1

    Topics: Bile Duct Diseases; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Clofibrate; Dilatation, Path

1980
Gallstones in patients with rheumatoid arthritis.
    The Journal of rheumatology, 1999, Volume: 26, Issue:7

    Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bezafibrate; C-Re

1999
Drugs and gallstones.
    Lancet (London, England), 1977, Jul-23, Volume: 2, Issue:8030

    Topics: Adult; Cholelithiasis; Clofibrate; Contraceptives, Oral, Synthetic; Estradiol Congeners; Female; Hum

1977
Who gets gallstones and why.
    Postgraduate medicine, 1979, Volume: 66, Issue:3

    Topics: Bilirubin; Cholelithiasis; Cholesterol; Clofibrate; Estrogens; Hemolysis; Indians, North American; O

1979
Drug interactions and side effects of hypolipidemic drugs.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:8

    Topics: Blood Coagulation; Cholelithiasis; Cholestyramine Resin; Clofibrate; Drug Interactions; Glucose; Hum

1979
Dissolution of human gallstone with clofibrate.
    The Journal of surgical research, 1978, Volume: 24, Issue:1

    Topics: Cholelithiasis; Clofibrate; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Solubilit

1978
Clofibrate therapy and gallstone induction.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:7

    Topics: Adult; Aged; Bile; Bile Acids and Salts; Cholelithiasis; Cholesterol; Clofibrate; Female; Humans; Hy

1978
[Anticholesteremic agents and cholelithiasis].
    Nihon rinsho. Japanese journal of clinical medicine, 1978, Volume: Suppl

    Topics: Animals; Cholelithiasis; Clofibrate; Humans; Rats

1978
The influence of dietary cholesterol on the lithogenesity of bile in rats treated with clofibrate.
    Hiroshima journal of medical sciences, 1978, Volume: 27, Issue:2

    Topics: Animals; Bile Acids and Salts; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Clofibrate; Female

1978
Prevalence of gallstones in hyperlipidemia and incidence during treatment with clofibrate and/or cholestyramine.
    Transactions of the Association of American Physicians, 1978, Volume: 91

    Topics: Cholelithiasis; Cholestyramine Resin; Clofibrate; Dietary Fats; Drug Interactions; Humans; Hyperlipi

1978
Hypolipidemic agents and gallstones.
    The Medical letter on drugs and therapeutics, 1977, Jun-03, Volume: 19, Issue:11

    Topics: Cholelithiasis; Cholestyramine Resin; Clofibrate; Colestipol; Humans; Polyamines

1977
[Iatrogenic cholelithiasis].
    Tijdschrift voor gastro-enterologie, 1977, Volume: 20, Issue:2

    Topics: Cholelithiasis; Clofibrate; Contraceptives, Oral; Dietary Fats; Gastrectomy; Humans; Iatrogenic Dise

1977
Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones.
    Gastroenterology, 1975, Volume: 69, Issue:4

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Clofibrate; Female; Humans; Hypercholesterolemia; Liver Cirrh

1975
Dissolution of gall-stones in vitro.
    Journal of the Indian Medical Association, 1991, Volume: 89, Issue:5

    Topics: Bile Acids and Salts; Cholelithiasis; Clofibrate; Heparin; Humans; In Vitro Techniques

1991
The present position concerning gallstone dissolution.
    Gut, 1974, Volume: 15, Issue:11

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol, Dietary; Cholesty

1974
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 12-1973.
    The New England journal of medicine, 1973, Mar-22, Volume: 288, Issue:12

    Topics: Acute Disease; Adult; Arteriosclerosis; Blood Protein Disorders; Cholecystitis; Cholelithiasis; Chro

1973
[Perspectives of conservative treatment and prevention of cholelithiasis].
    Ceskoslovenska gastroenterologie a vyziva, 1973, Volume: 27, Issue:3

    Topics: Bile Acids and Salts; Cholelithiasis; Cholestyramine Resin; Clofibrate; Female; Humans; Phosphatidyl

1973
Effect of chlorophenoxyisobutyrate on lipids in serum and hepatic bile.
    The Tohoku journal of experimental medicine, 1973, Volume: 110, Issue:4

    Topics: Aged; Bile; Cholelithiasis; Cholesterol; Clofibrate; Female; Humans; Male; Middle Aged; Phospholipid

1973
Effects of clofibrate and of an estrogen-progestin combination on fasting biliary lipids and cholic acid kinetics in man.
    Gastroenterology, 1974, Volume: 66, Issue:4

    Topics: Bile; Bile Acids and Salts; Carbon Radioisotopes; Cholecystectomy; Cholecystography; Cholelithiasis;

1974
Alimentary production of gallstones in hamsters. 25. Inhibition of production of cholesterol gallstones by 2-(p-chlorophenoxy)-isobutyric acid ethyl ester (clofibrate).
    Zeitschrift fur Ernahrungswissenschaft, 1972, Volume: 11, Issue:2

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Cholelithiasis; Cholesterol; Clofibrate; Cr

1972
Induced alterations in composition of bile of persons having cholelithiasis.
    Gastroenterology, 1971, Volume: 61, Issue:4

    Topics: Bile; Bile Acids and Salts; Body Weight; Cholecystokinin; Cholelithiasis; Cholesterol; Cholestyramin

1971
[Pathologic and therapeutic similarities between arteriosclerosis and lithiasic cholecystitis].
    Annales de medecine interne, 1971, Volume: 122, Issue:10

    Topics: Acetamides; Aminosalicylic Acids; Animals; Arteriosclerosis; Aspirin; Cholecystitis; Cholelithiasis;

1971
[Experimental therapy of gallbladder lithiasis. Preventive and curative effects of various drugs in mice].
    Archives francaises des maladies de l'appareil digestif, 1970, Volume: 59, Issue:6

    Topics: Animals; Aspirin; Cholelithiasis; Cholestyramine Resin; Clofibrate; Dehydrocholic Acid; Hydantoins;

1970