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clofibrate and Breast Cancer

clofibrate has been researched along with Breast Cancer in 9 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Research Excerpts

ExcerptRelevanceReference
"A patient developed severe hypertriglyceridemia while on treatment with Tamoxifen after a mastectomy and with a statin for a lipid disorder."7.70Tamoxifen and hypertriglyceridemia. ( Jonkers, GH, 1999)
"Clofibrate treatment significantly induced PPARα DNA binding activity, and remarkably reduced cyclooxygenase-2/PGE2 and 5-lipoxygenase/LTB4 inflammatory pathways."5.43Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer. ( Chandran, K; Goswami, S; Sharma-Walia, N, 2016)
"It was shown that in patients with breast cancer and cancer of the corpus uteri in the presence of hypercholesterinemia and hypertriglyceridemia the level of blood somatomedin activity would be 3--5 times the control values, being 3."5.26[Effect of phenformin and miscleron on the blood somatomedin activity level in breast cancer]. ( Bershteĭn, LM; Dil'man, VM; Ostroumova, MN; Vasil'eva, IA, 1980)
"A patient developed severe hypertriglyceridemia while on treatment with Tamoxifen after a mastectomy and with a statin for a lipid disorder."3.70Tamoxifen and hypertriglyceridemia. ( Jonkers, GH, 1999)
"The effects of administration of phenformin and clofibrate to 32 breast cancer patients who underwent radical mastectomy and suffered from hormonal metabolic disturbances involving a decline in immunologic response were investigated."3.66Metabolic immunodepression and metabolic immunotherapy: an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances. ( Berstein, LM; Buslaeva, VP; Dilman, VM; Fedorov, SN; Kondratjev, VB; Nemirovsky, VS; Nikiforov, YF; Ostroumova, MN; Poroshina, TE; Seleznev, IK; Semiglazov, VF; Tsyrlina, EV; Vasilyeva, IA, 1982)
"Some preliminary results of using phenformin and miscleron in 17 breast cancer patients, previously radically operated upon, have been assessed as being characterized by metabolic disturbances associated with the reduced cell immunity level."3.66[Effect of fenformin and miscleron on the delayed hypersensitivity reaction in breast cancer patients]. ( Bershteĭn, LM; Buslaeva, VP; Kondrat'ev, VB; Ostroumova, MN; Semiglazov, VF, 1980)
"Clofibrate treatment significantly induced PPARα DNA binding activity, and remarkably reduced cyclooxygenase-2/PGE2 and 5-lipoxygenase/LTB4 inflammatory pathways."1.43Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer. ( Chandran, K; Goswami, S; Sharma-Walia, N, 2016)
"The promotion of proliferation in breast cancer cell lines following PPARalpha activation was in stark contrast to the effects of PPARgamma-activating ligands that decrease proliferation in human breast cancer cells."1.31Peroxisome proliferator-activated receptor alpha in the human breast cancer cell lines MCF-7 and MDA-MB-231. ( Holman, NA; Lee, WJ; May, FJ; Monteith, GR; Roberts-Thomson, SJ; Robinson, JA; Suchanek, KM, 2002)
"It was shown that in patients with breast cancer and cancer of the corpus uteri in the presence of hypercholesterinemia and hypertriglyceridemia the level of blood somatomedin activity would be 3--5 times the control values, being 3."1.26[Effect of phenformin and miscleron on the blood somatomedin activity level in breast cancer]. ( Bershteĭn, LM; Dil'man, VM; Ostroumova, MN; Vasil'eva, IA, 1980)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Chen, H2
Liu, Y1
Yin, Z1
Wang, Y1
Qian, Y1
Chandran, K1
Goswami, S1
Sharma-Walia, N1
Suchanek, KM1
May, FJ1
Robinson, JA1
Lee, WJ1
Holman, NA1
Monteith, GR1
Roberts-Thomson, SJ1
Dilman, VM2
Berstein, LM2
Ostroumova, MN4
Fedorov, SN1
Poroshina, TE2
Tsyrlina, EV2
Buslaeva, VP2
Semiglazov, VF2
Seleznev, IK1
Vasilyeva, IA1
Kondratjev, VB1
Nemirovsky, VS1
Nikiforov, YF1
Vasil'eva, IA1
Bershteĭn, LM3
Dil'man, VM2
Kondrat'ev, VB1
Jonkers, GH1
Bobrov, IuF1
Kovaleva, IG2
Revskoy, SY1

Other Studies

9 other studies available for clofibrate and Breast Cancer

ArticleYear
Homologous repair deficiency-associated genes in invasive breast cancer revealed by WGCNA co-expression network analysis and genetic perturbation similarity analysis.
    Cell cycle (Georgetown, Tex.), 2023, Volume: 22, Issue:9

    Topics: Breast; Breast Neoplasms; Clofibrate; Female; Humans; Molecular Docking Simulation; Protein Serine-T

2023
Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer.
    Oncotarget, 2016, Mar-29, Volume: 7, Issue:13

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Clofibrate; Female; H

2016
Peroxisome proliferator-activated receptor alpha in the human breast cancer cell lines MCF-7 and MDA-MB-231.
    Molecular carcinogenesis, 2002, Volume: 34, Issue:4

    Topics: Breast Neoplasms; Cell Division; Clofibrate; Female; Gene Expression Regulation, Neoplastic; Humans;

2002
Metabolic immunodepression and metabolic immunotherapy: an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances.
    Oncology, 1982, Volume: 39, Issue:1

    Topics: Age Factors; Body Weight; Breast Neoplasms; Clofibrate; Female; Hormones; Humans; Hypersensitivity,

1982
[Effect of phenformin and miscleron on the blood somatomedin activity level in breast cancer].
    Voprosy onkologii, 1980, Volume: 26, Issue:9

    Topics: Adult; Aged; Breast Neoplasms; Clofibrate; Female; Humans; Hyperlipidemias; Middle Aged; Phenformin;

1980
[Effect of fenformin and miscleron on the delayed hypersensitivity reaction in breast cancer patients].
    Voprosy onkologii, 1980, Volume: 26, Issue:12

    Topics: Breast Neoplasms; Clofibrate; Dinitrochlorobenzene; Drug Therapy, Combination; Female; Humans; Hyper

1980
Tamoxifen and hypertriglyceridemia.
    The Netherlands journal of medicine, 1999, Volume: 55, Issue:2

    Topics: Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Atorvastatin; Breast Neoplasms; Clofibrat

1999
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
    Voprosy onkologii, 1975, Volume: 21, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C

1975
Age-dependent metabolic immunodepression and cancer.
    IARC scientific publications, 1985, Issue:58

    Topics: Age Factors; Biguanides; Blood Viscosity; Breast Neoplasms; Cholesterol; Clofibrate; Female; Humans;

1985