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clofibrate and Body Weight

clofibrate has been researched along with Body Weight in 176 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"This study analyzed the effects of the chronic administration of clofibrate, a peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist, on the development and established hemodynamic, morphologic, metabolic, and renal manifestations of hyperthyroidism in rats."7.74Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats. ( Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F, 2008)
"Some patients with familial hypercholesterolemia (FHC, type II) are highly responsive to the cholesterol-lowering effect of clofibrate, while others are not only resistant to this effect but may even show an increase in plasma beta-lipoproteins."7.65Pharmacokinetics of clofibrate in familial hypercholesterolemia. ( Boulet, L; Davignon, J; Pichardo, R, 1977)
"This study analyzed the effects of the chronic administration of clofibrate, a peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist, on the development and established hemodynamic, morphologic, metabolic, and renal manifestations of hyperthyroidism in rats."3.74Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats. ( Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F, 2008)
"All animals were fed HFD but only 2/12 animals were fed HFD plus clofibrate-developed fatty liver."3.72Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver. ( Akbiyik, F; Bozkaya, H; Cinar, K; Demirpence, E; Haziroglu, R; Ozsullu, T; Tunca, R; Uzunalimoglu, O; Yurdaydin, C, 2004)
"Rainbow trout (Salmo gairdneri), average body weight of 450 g, were treated with 15, 25, or 35 mg/kg of ciprofibrate via intraperitoneal injection every other day for 2 to 3 weeks."3.68Induction of peroxisome proliferation in rainbow trout exposed to ciprofibrate. ( Baldwin, LA; Calabrese, EJ; Kostecki, PT; Yang, JH, 1990)
"The effects of administration of phenformin and clofibrate to 32 breast cancer patients who underwent radical mastectomy and suffered from hormonal metabolic disturbances involving a decline in immunologic response were investigated."3.66Metabolic immunodepression and metabolic immunotherapy: an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances. ( Berstein, LM; Buslaeva, VP; Dilman, VM; Fedorov, SN; Kondratjev, VB; Nemirovsky, VS; Nikiforov, YF; Ostroumova, MN; Poroshina, TE; Seleznev, IK; Semiglazov, VF; Tsyrlina, EV; Vasilyeva, IA, 1982)
"Some patients with familial hypercholesterolemia (FHC, type II) are highly responsive to the cholesterol-lowering effect of clofibrate, while others are not only resistant to this effect but may even show an increase in plasma beta-lipoproteins."3.65Pharmacokinetics of clofibrate in familial hypercholesterolemia. ( Boulet, L; Davignon, J; Pichardo, R, 1977)
"Hens treated with clofibrate also had lower mRNA concentrations of fatty acid synthase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, and low-density lipoprotein receptor, proteins involved in fatty acid biosynthesis and cholesterol biosynthesis and uptake, than hens fed the control diet (P<0."2.73Effects of clofibrate treatment in laying hens. ( Brandsch, C; Eder, K; Haase, K; Kluge, H; König, B; Stangl, GI, 2007)
" Patients receiving clofibrate and both estrogen dosage groups had the highest incidence of cholecystitis or cholelithiasis."2.64Gallbladder disease as a side effect of drugs influencing lipid metabolism. Experience in the Coronary Drug Project. ( , 1977)
"Hypertriglyceridemia has been recently recognized as a vascular risk factor, based on both clinical and experimental findings."2.38Pharmacological control of hypertriglyceridemia. ( Franceschini, G; Paoletti, R, 1993)
"Clofibrate treatment was shown to concomitantly decrease the liver levels of HNF1α, HNF4α and PCSK9 mRNA, as well as serum PCSK9, TAGs and total cholesterol concentrations in CRF rats."1.43Up-regulation of Hnf1α gene expression in the liver of rats with experimentally induced chronic renal failure - A possible link between circulating PCSK9 and triacylglycerol concentrations. ( Rutkowski, B; Sucajtys-Szulc, E; Swierczynski, J; Szolkiewicz, M, 2016)
"Clofibrate did not increase the frequency of MNed cells in the bone marrow in the 14-day study, whereas a slight increase was observed at the highest dose in the 28-day study."1.42Repeated dose liver micronucleus assay using clofibrate in young adult rats. ( Fujii, W; Hori, H; Kawasako, K; Takashima, R; Takayanagi, T; Tanaka, Y; Wako, Y, 2015)
"Pigs treated with clofibrate had higher relative mRNA concentrations of OCTN2 in liver (3."1.35Clofibrate treatment up-regulates novel organic cation transporter (OCTN)-2 in tissues of pigs as a model of non-proliferating species. ( Eder, K; Fischer, M; Geissler, S; Hirche, F; Kluge, H; Luci, S; Ringseis, R; Spielmann, J; Wen, G, 2008)
"Pigs treated with clofibrate had heavier livers, moderately increased mRNA concentrations of various PPAR-alpha target genes in liver and adipose tissue, a higher concentration of 3-hydroxybutyrate, and markedly lower concentrations of triglycerides and cholesterol in plasma and lipoproteins than control pigs (P < 0."1.34Clofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs. ( Eder, K; Giemsa, B; Kluge, H; Luci, S, 2007)
"Pigs treated with clofibrate had higher hepatic activities of T(3)- and T(4)-UDP glucuronosyltransferases (UGT) and lower concentrations of total and free T(4) and total T(3) in plasma than control pigs (P < 0."1.33Clofibrate increases hepatic triiodothyronine (T3)- and thyroxine (T4)-glucuronosyltransferase activities and lowers plasma T3 and T4 concentrations in pigs. ( Eder, K; Hirche, F; Kluge, H; Luci, S, 2006)
" Analysis of dose-response exposures to DEHP by reverse transcription (RT)-PCR confirm these results and also shows that GRP58 is not altered in kidney or testis."1.30A glucose-regulated protein, GRP58, is down-regulated in C57B6 mouse liver after diethylhexyl phthalate exposure. ( Gill, SS; Muhlenkamp, CR, 1998)
"Clofibrate-treated rats showed typical changes with increases in hepatic PCoA oxidase and CAT activity (5."1.30Investigation of the potential of conjugated linoleic acid (Cla) to cause peroxisome proliferation in rats. ( Jones, PA; Lea, LJ; Pendlington, RU, 1999)
"Incidences of hepatocellular carcinomas were 75% (9/12, P < 0."1.30Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation. ( Hagiwara, A; Hasegawa, R; Imaida, K; Ito, N; Sano, M; Shirai, T; Tamano, S, 1999)
"The hypolipidemic drug ethyl chlorophenoxyisobutyrate (clofibrate) is known to induce peroxisome proliferation and to be carcinogenic after long term administration to rats and mice."1.29Effects of chronic administration of the peroxisome proliferator, clofibrate, on cytosolic acetyl-CoA hydrolase in rat liver. ( Isohashi, F; Nakanishi, Y; Okamoto, K, 1993)
"Uracil was administered during weeks 9-11 at a dietary level of 3."1.28Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. ( Asakawa, E; Fukushima, S; Hagiwara, A; Ogiso, T; Tamano, S, 1990)
"Ciprofibrate was fed to female Sprague-Dawley rats at concentrations of 0, 0."1.28Effect of the peroxisome proliferator ciprofibrate on hepatic DNA synthesis and hepatic composition following partial hepatectomy in rats. ( Chow, CK; Glauert, HP; Srinivasan, SR, 1990)
"Clofibrate was more than 10 times less potent than YM-95831 in the hypolipidemic activity."1.27Aminophenyl ether compound (YM-95831), a new hypolipidemic agent with a high density lipoprotein elevating activity in rats. ( Maeno, H; Nitatori, R; Ohata, I; Sakamoto, N, 1983)
" at an overall dosage of 1275 mg/kg, 2-(p-chlorophenoxy)propionic acid (0."1.27Effect of phenoxy acids on rat liver regeneration. ( Gershbein, LL, 1984)
"Clofibrate treatment decreased drastically the activity of serum postheparin lipoprotein lipase of rats fed with fat-free test diet but had no effect on hepatic lipase."1.27Clofibrate decreases jejunal cholesterol synthesis and activity of postheparin plasma lipoprotein lipase in the rat. ( Kuusi, T; Miettinen, TA; Strandberg, TE; Tilvis, RS, 1983)
"Nafenopin was also added to either a high carbohydrate (70% of kilocalories from glucose) or high fat (70% of kilocalories from lard) diet and fed to rats for either 1 or 3 weeks."1.27The effect of three hypolipidemic drugs on catalase activity and peroxisomal and mitochondrial palmitate oxidation in rat cardiac and skeletal muscle. ( MacDonald, RS; Swan, PB, 1986)
"Clofibrate caused an increase in liver weight without affecting body weight."1.27Alterations in rat serum lipids and apolipoproteins following clofibrate treatment. ( Dashti, N; Ontko, JA, 1983)
"Rats treated with clofibrate revealed foci of cellular alteration that were more often basophilic and occurred slightly sooner (wk 42) than those in untreated controls (wk 60)."1.27Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility. ( Greaves, P; Irisarri, E; Monro, AM, 1986)
"Clofibrate was used as the standard product."1.26Toxicological studies of plafibride. Part 2: Subacute and subchronic toxicity in rats and chronic toxicity in dogs. ( Bruseghini, L; Sanfeliu, C; Zapatero, J, 1981)
"Niceritrol treatment was associated with increased blood glucose, decreased K value, elevated fasting serum insulin and serum insulin at 60 min during IVGTT."1.26Changes in glucose tolerance and plasma insulin during lipid-lowering treatment with diet, clofibrate and niceritrol. ( Hellsing, K; Lithell, H; Vessby, B, 1982)
"Clofibrate treatment also induced an increase of many times in the activities of mitochondrial alpha-GPD and carnitine acyltransferases, the effect increasing with the dose used."1.26Effect of clofibrate and gemfibrozil on the activities of mitochondrial carnitine acyltransferases in rat liver. Dose--response relations. ( Kähönen, MT; Ylikahri, RH, 1979)
"Ciprofibrate was convenient to take and was without subjective side effects."1.26Dose-response study of the effect of ciprofibrate on serum lipoprotein concentrations in hyperlipoproteinaemia. ( Olsson, AG; Orö, L, 1982)
"The pathogenesis of arteriosclerosis is unknown."1.26[Lipid lowering treatment and regression of arteriosclerosis (author's transl)]. ( Greten, H; Klose, G, 1980)
"If the hypercholesterolemia was continued for 18 months, no significant change in the cholesterol ester content in the aorta occurred; in the coronary arteries there was a significant decrease in these older pigs."1.26Experimental atherosclerosis in hypercholesterolemic mini-pigs. Regression of cholesterol ester accumulation in aorta and coronary arteries after treatment with clofibrate, beta-pyridylcarbinol or a normo-lipidemic diet. ( Jacobsson, L; Lundholm, L, 1982)
"Clofibrate treatment resulted in a reduction of plasma cholesterol, hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities."1.26Effect of probucol on cholesterol metabolism in the rat. ( Holets, RJ; Kottke, BA; Li, JR, 1980)
"Bezafibrate is a potent lipid-lowering agent of the new generation."1.26Clinical experience with bezafibrate. ( Hausmann, L; Kaffarnik, H; Mühlfellner, G; Mühlfellner, O; Schneider, J; Schubotz, R, 1980)
" No significant differences were seen in the pharmacokinetic parameters observed for antipyrine, a drug which is less than 10% bound to plasms proteins."1.25Pharmacokinetics of drugs in patients with the nephrotic syndrome. ( Azarnoff, DL; Cohlmia, JB; Gugler, R; Huffman, DH; Shoeman, DW, 1975)
" In 6 patients given cholestyramine together with clofibrate, there was no significant alteration in fasting plasma CPIB levels, 24-hour urinary and faecal excretion of CPIB or in the half-life and pool size of the drug."1.25Lack of effect of cholestyramine on the pharmacokinetics of clofibrate in man. ( Ahrens, EH; Sedaghat, A, 1975)
"Nephrotic syndrome was induced by a single i."1.25Efficacy and interactions of oxandrolone, halo-fenate and clofibrate in a factorial study on experimental acute nephrotic hyperlipidemia. ( Edwards, KD; Schapel, GJ, 1975)

Research

Studies (176)

TimeframeStudies, this research(%)All Research%
pre-1990133 (75.57)18.7374
1990's29 (16.48)18.2507
2000's10 (5.68)29.6817
2010's3 (1.70)24.3611
2020's1 (0.57)2.80

Authors

AuthorsStudies
Baggaley, KH1
Fears, R1
Hindley, RM1
Morgan, B1
Murrell, E1
Thorne, DE1
Wyrick, SD2
Hall, IH2
Piantadosi, C2
Fenske, CR1
Ishaq, KS1
Bennett, GB1
Houlihan, WJ1
Mason, RB1
Engstrom, RG1
Ashton, MJ1
Ashford, A1
Loveless, AH1
Riddell, D1
Salmon, J1
Stevenson, GV1
Xie, YD1
Chen, ZZ1
Shao, LH1
Wang, QT1
Li, N1
Lu, WF1
Xu, YH1
Gao, YQ1
Guo, LY1
Liu, HL1
Li, YP1
Yang, GD1
Bian, XL1
Chen, YT1
Jenq, CC1
Hsu, CK1
Yu, YC1
Chang, CH1
Fan, PC1
Pan, HC1
Wu, IW1
Cherng, WJ1
Chen, YC1
Takayanagi, T1
Takashima, R1
Wako, Y1
Kawasako, K1
Tanaka, Y1
Hori, H1
Fujii, W1
Sucajtys-Szulc, E1
Szolkiewicz, M1
Swierczynski, J1
Rutkowski, B1
STRISOWER, EH1
STRISOWER, B1
Savolainen, K1
Kotti, TJ1
Schmitz, W1
Savolainen, TI1
Sormunen, RT1
Ilves, M1
Vainio, SJ1
Conzelmann, E1
Hiltunen, JK1
Akbiyik, F1
Cinar, K1
Demirpence, E1
Ozsullu, T1
Tunca, R1
Haziroglu, R1
Yurdaydin, C1
Uzunalimoglu, O1
Bozkaya, H1
Luci, S3
Kluge, H4
Hirche, F2
Eder, K4
Giemsa, B1
König, B1
Haase, K1
Brandsch, C1
Stangl, GI1
Rodríguez-Gómez, I1
Cruz, A1
Moreno, JM1
Soler, A1
Osuna, A1
Vargas, F1
Ringseis, R1
Spielmann, J1
Fischer, M2
Geissler, S1
Wen, G1
Raheja, KL1
Lincheer, WG1
Cho, C1
Numoto, S1
Furukawa, K2
Furuya, K1
Williams, GM2
Romics, L1
Dashti, N1
Ontko, JA1
Kunitomo, M3
Takaoka, K1
Matsumoto, J1
Iwai, H1
Bando, Y1
Fort, FL1
Stein, HH1
Langenberg, K1
Lewkowski, JP1
Heyman, IA1
Kesterson, JW1
Calatayud, JM1
Ohata, I1
Sakamoto, N1
Nitatori, R1
Maeno, H1
Rao, MS1
Lalwani, ND1
Watanabe, TK1
Reddy, JK1
Gershbein, LL1
Jacobsson, L1
Lundholm, L1
Klose, G1
Greten, H1
Miettinen, TA2
Huttunen, JK1
Ehnholm, C1
Kumlin, T1
Mattila, S1
Naukkarinen, V1
Lang, PD2
Vollmar, J2
Strandberg, TE1
Kuusi, T1
Tilvis, RS1
Nyitray, M1
Szaszovsky, E1
Druga, A1
Olsson, AG1
Orö, L1
Pissarek, D1
Panzram, G1
Lundershausen, R1
Adolph, W1
Senf, L1
Vessby, B3
Lithell, H3
Hellsing, K3
Ostlund-Lindqvist, AM1
Gustafsson, IB1
Boberg, J2
Ledermann, H1
Dilman, VM1
Berstein, LM1
Ostroumova, MN1
Fedorov, SN1
Poroshina, TE1
Tsyrlina, EV2
Buslaeva, VP1
Semiglazov, VF1
Seleznev, IK1
Vasilyeva, IA1
Kondratjev, VB1
Nemirovsky, VS1
Nikiforov, YF1
Mochizuki, Y1
Sawada, N1
Krause, BR1
Hartman, AD1
Wirth, A1
Middelhoff, G1
Braeuning, C1
Schlierf, G1
Mizugaki, M1
Nishimaki, T1
Yamamoto, H1
Sagi, M1
Yamanaka, H1
Vogelberg, KH2
Cicmir, I1
Heggen, ME1
Sterner, W2
Chibanguza, G1
Metz, G1
Zapatero, J1
Sanfeliu, C1
Bruseghini, L1
Stratmann, FW1
Holler, HD1
Hofmann, H1
Schubotz, R1
Schneider, J1
Hausmann, L1
Mühlfellner, G1
Mühlfellner, O1
Kaffarnik, H1
Arteaga, A1
Maiz, A1
Lathrop, R1
Brook, JG1
Lavy, A1
Aviram, M1
Zinder, O1
Li, JR1
Holets, RJ1
Kottke, BA1
Barnard, SD1
Molello, JA1
Caldwell, WJ1
Lebeau, JE1
Shand, JH2
West, DW2
Hamdoune, M1
Duclos, S1
Mounie, J1
Santona, L1
Lhuguenot, JC1
Magdalou, J2
Goudonnet, H1
Stanko, RT1
Sekas, G1
Isaacson, IA1
Clarke, MR1
Billiar, TR1
Paul, HS1
Nakanishi, Y1
Okamoto, K1
Isohashi, F1
Wysynski, AM1
Baldwin, LA2
Leonard, DA1
Calabrese, EJ2
Franceschini, G1
Paoletti, R1
Yamoto, T1
Ohashi, Y1
Furukawa, T1
Teranishi, M1
Manabe, S1
Makita, T1
Simpson, AE1
Brammar, WJ1
Pratten, MK1
Elcombe, CR1
Muhlenkamp, CR1
Gill, SS1
Kim, DJ1
Lee, KK1
Hong, JT1
Sano, M1
Hagiwara, A2
Tamano, S2
Hasegawa, R1
Imaida, K1
Ito, N2
Shirai, T1
Dobashi, K1
Asayama, K1
Nakane, T1
Hayashibe, H1
Kodera, K1
Uchida, N1
Nakazawa, S1
Shoda, T1
Mitsumori, K1
Onodera, H1
Toyoda, K1
Uneyama, C1
Imazawa, T1
Hirose, M1
Jones, PA1
Lea, LJ1
Pendlington, RU1
Qu, B1
Halliwell, B1
Ong, CN1
Lee, BL1
Li, QT1
Pugh, G1
Isenberg, JS1
Kamendulis, LM1
Ackley, DC1
Clare, LJ1
Brown, R1
Lington, AW1
Smith, JH1
Klaunig, JE1
Hamano, T1
Kobayashi, K1
Sakairi, T1
Hayashi, M1
Mutai, M1
Cayen, MN1
Dubuc, J1
Dvornik, D1
Gotoh, M2
Griffin, C1
Hruban, Z3
Rider, AK1
Stone, MC1
Thorp, JM1
Wain, JS1
Schwandt, P2
Weisweiler, P2
Neureuther, G1
Wilkening, J1
Miyazawa, S1
Sakurai, T1
Imura, M1
Hashimoto, T1
Hedstrand, H2
Pichardo, R1
Boulet, L1
Davignon, J4
Gianoulakis, C2
Passerini, L1
Lis, M1
Chrétien, M2
Koschinsky, T2
Gries, FA2
Hansen, W1
Nijssen, J1
Beckmann, R1
Luepker, RV2
Smith, LK2
Rothchild, SS2
Gillis, A2
Kochman, L2
Warbasse, JR2
Wallentin, L1
Stejskal, R1
Itabashi, M1
Stanek, J1
Ljunghall, S1
Falkensammer, C1
Singhal, AK1
Brill, DR1
Schaffner, CP1
Nestruck, AC1
Kähönen, MT1
Ylikahri, RH1
Fredj, G1
Clenet, M1
Cuchet, P2
Rousselet, F1
Rozé, C2
Christiansen, RZ1
Norseth, J1
Christiansen, N1
Kutz, K1
Schulte, A1
Just, C1
Lindstaedt, H1
Reiter, B1
Gustafson, A1
Chhabra, S2
Rasheed, BK1
Kurup, CK3
Magnusson, O4
Hayashi, E3
Yamada, J1
Terada, M1
Sato, M1
Rees, ED1
Hamilton, RD1
Kanner, IF1
Wasson, S1
Hearn, T1
Goldberg, AP1
Mellon, WS1
Witiak, DT3
Feller, DR3
Souchard, M1
Vaille, C1
Debray, C1
Owen, JS1
Billimoria, JD1
Markwell, MA1
Bieber, LL1
Tolbert, NE1
Lenhard, P1
Wolfram, G2
Gugler, R1
Shoeman, DW1
Huffman, DH1
Cohlmia, JB1
Azarnoff, DL2
Sedaghat, A1
Ahrens, EH1
Hosokawa, T1
Suzuki, K1
sawada, M1
Ando, K1
Schapel, GJ1
Edwards, KD1
Dil'man, VM1
Bershteĭn, LM1
Bobrov, IuF1
Kovaleva, IG1
Bohmer, T1
Olsson, U1
Garberg, P1
Lundgren, B1
Andersson, K1
Hultenby, K1
Bergstrand, A1
Eriksson, AM1
Högberg, J1
DePierre, JW1
Watanabe, T1
Okawa, S1
Itoga, H1
Imanaka, T1
Suga, T1
Shoji, S1
Gerbracht, U1
Bursch, W1
Kraus, P1
Putz, B1
Reinacher, M1
Timmermann-Trosiener, I1
Schulte-Hermann, R2
Chinje, E1
Gibson, GG2
Sato, A1
Watanabe, K1
Fukuzumi, H1
Hase, K1
Ishida, F1
Kamei, T1
Schön, HJ1
Kremser, K1
Prager, C1
Kramar, R1
Yamaguchi, Y1
Yamada, K1
Kitagawa, S1
Ogiso, T1
Asakawa, E1
Fukushima, S1
Butler, EG1
Ichida, T1
Maruyama, H1
Yang, JH1
Kostecki, PT1
Srinivasan, SR1
Chow, CK1
Glauert, HP1
Makowska, JM1
Anders, C1
Goldfarb, PS1
Bonner, F1
Esbenshade, TA1
Kamanna, VS1
Newman, HA1
Tortorella, V1
Mohan, PF1
Cleary, MP1
Hosokawa, S1
Tatematsu, M1
Aoki, T1
Nakanowatari, J1
Igarashi, T1
Ujházy, E1
Onderová, E1
Horáková, M1
Bencová, E1
Durisová, M1
Nosál, R1
Balonová, T1
Zeljenková, D1
Greaves, P1
Irisarri, E1
Monro, AM1
Fournel, S1
Pinon, P1
Siest, G1
Bergseth, S1
Christiansen, EN1
Bremer, J1
Silva, MH1
Wixtrom, RN1
Hammock, BD1
Cibelli, A1
Stefanini, S1
Ceru, MP1
Ohta, F1
Gaudemer, F1
Lutton, C1
Wójcicki, J1
Samochowiec, L1
Bartłomowicz, B1
Hinek, A1
Jaworska, M1
Gawrońska-Szklarz, B1
MacDonald, RS1
Swan, PB1
Hoogwerf, BJ1
Peters, JR1
Frantz, ID1
Hunninghake, DB1
Wilson, DE1
Lees, RS1
Tomita, T2
Yamamura, Y1
Nagakura, T2
Levy, RI1
von Löwis, P1
Klemens, UH1
Albrink, MJ1
Krishnakantha, TP1
Schultz, A1
Takeshita, R1
Dujovne, CA1
Hurwitz, A1
Kauffman, RE1
Ciświcka-Sznajderman, M1
Page, W1
Vanderveiken, F1
Van Melsen, A1
Van Melsen, Y1
Vastesaeger, M1
Muggeo, M1
Fedele, D1
Tiengo, A1
Crepaldi, G2
Irsigler, K2
Flegel, U2
Kühn, P1
Schubert, H1
Iván, E1
Biro, L1
Székely, L1
Goodman, DS1
Noble, RP1
Dell, RB1
Kritchevsky, D1
Tepper, SA1
Scott, PJ1
Weber, K1
Braun-Falco, O1
Carter, EA1
Isselbacher, KJ1
Fellin, R1
Briani, G1
Bondesson, G3
Hedbom, C1
Högberg, T1
Stjernström, NE3
Carlson, LA1
Lewis, NJ1
Poochikian, GK1
Fenderson, RW1
Sekowski, I1
Mohan, C1
Deutsch, S1
Benjamin, F1
Samuel, P1
Slesers, A1
Chou, SF1
Gronowitz, S2
Svenson, R1
Dafgård, B1
Kim, DN1
Lee, KT1
Reiner, JM1
Thomas, WA1
Berkowitz, D1
Mertz, DP1
Schwoerer, P1
Babucke, G1
Kannel, WB1
Garcia, MJ1
McNamara, PM1
Pearson, G1
Bagdade, JD1
Bierman, EL1
Porte, D1
Thistle, JL1
Schoenfield, LJ1
Segall, MM1
Fosbrooke, AS1
Lloyd, JK1
Wolff, OH1
Page, IH1
Lewis, LA1
Kokatnur, MG1
Malcom, GT1
Duncan, CH1
Best, MM1
Casdorph, HR1
Grafnetter, D1
Mrhová, O1
Janda, J1
Aubry, F1
Lapierre, YL1
Noël, C1
Maha, GE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000482]Phase 30 participants Interventional1965-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for clofibrate and Body Weight

ArticleYear
Drug treatment of hyperlipoproteinaemia.
    Therapia Hungarica (English edition), 1983, Volume: 31, Issue:4

    Topics: Body Weight; Clofibrate; Gonadal Steroid Hormones; Humans; Hyperlipoproteinemias; Hypolipidemic Agen

1983
Pharmacological control of hypertriglyceridemia.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:3

    Topics: Body Weight; Cardiovascular Diseases; Clofibrate; Exercise; Fatty Acids, Omega-3; Humans; Hypertrigl

1993
Dietary and drug treatment of hyperlipidemia in diabetes.
    Diabetes, 1974, Volume: 23, Issue:11

    Topics: Arteriosclerosis; Blood Protein Disorders; Body Weight; Cholestyramine Resin; Clofibrate; Diabetes M

1974

Trials

16 trials available for clofibrate and Body Weight

ArticleYear
Effects of clofibrate treatment in laying hens.
    Poultry science, 2007, Volume: 86, Issue:6

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Chickens; Cholesterol

2007
Effect of long-term antihypertensive and hypolipidemic treatment on high density lipoprotein cholesterol and apolipoproteins A-I and A-II.
    Atherosclerosis, 1980, Volume: 36, Issue:2

    Topics: Antihypertensive Agents; Apolipoproteins; Body Weight; Cholesterol; Clofibrate; Humans; Hyperlipopro

1980
[Intensified therapy of newly detected maturity onset diabetes].
    Endokrinologie, 1980, Volume: 75, Issue:1

    Topics: Biguanides; Body Weight; Clofibrate; Diabetes Mellitus; Diet, Diabetic; Female; Glucose Tolerance Te

1980
Treatment of familial hypercholesterolemia with a combination of bezafibrate and guar.
    Atherosclerosis, 1982, Volume: 45, Issue:3

    Topics: Adult; Apolipoproteins; Bezafibrate; Body Weight; Cholesterol; Cholesterol, LDL; Clofibrate; Clofibr

1982
[The influence of clofibrate on elevated serum lactate levels in diabetic patients treated with biguanides (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:4

    Topics: Adult; Biguanides; Body Weight; Clofibrate; Diabetes Mellitus; Enzymes; Female; Humans; Hypoglycemic

1980
[Treatment of primary hyperlipoproteinemias of type IIB and IV with butylbiguanide and clofibrate (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1977, May-20, Volume: 119, Issue:20

    Topics: Adult; Aged; Biguanides; Blood Glucose; Body Weight; Buformin; Cholesterol; Clofibrate; Drug Therapy

1977
Management of hypercholesterolemia: evaluation of practical clinical approaches in healthy young adults.
    The American journal of cardiology, 1978, Volume: 41, Issue:3

    Topics: Adult; Body Weight; Cholesterol; Clofibrate; Dietary Fats; Female; Humans; Hypercholesterolemia; Lip

1978
Gallbladder disease as a side effect of drugs influencing lipid metabolism. Experience in the Coronary Drug Project.
    The New England journal of medicine, 1977, 05-26, Volume: 296, Issue:21

    Topics: Adult; Age Factors; Anticholesteremic Agents; Body Height; Body Weight; Cholecystitis; Cholelithiasi

1977
Effects of clofibrate on glucose tolerance, serum insulin, serum lipoproteins and plasma fibrinogen.
    European journal of clinical pharmacology, 1977, Aug-17, Volume: 12, Issue:1

    Topics: Blood Glucose; Blood Sedimentation; Body Weight; Cholesterol; Clinical Trials as Topic; Clofibrate;

1977
[New drug combination for medical management of hyperlipemia: clinical study].
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:12

    Topics: Aged; Blood Glucose; Body Weight; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid;

1977
Halofenate in the treatment of type II hyperlipoproteinemia. Double blind comparison with clofibrate.
    Atherosclerosis, 1976, Volume: 24, Issue:3

    Topics: Adult; Blood Chemical Analysis; Body Weight; Cholesterol; Clinical Trials as Topic; Clofibrate; Fema

1976
[Treatment of primary hyperlipoproteinemia type IIb and IV. Comparison of the lipid lowering effect of phenformin, clofibrate, and a combination of both (author's transl)].
    Medizinische Klinik, 1977, Sep-23, Volume: 72, Issue:38

    Topics: Adult; Body Weight; Cholesterol; Clofibrate; Drug Therapy, Combination; Female; Humans; Hyperlipidem

1977
Management of type IV hyperlipoproteinemia. Evaluation of practical clinical approaches.
    Annals of internal medicine, 1976, Volume: 84, Issue:1

    Topics: Adult; Arteriosclerosis; Body Weight; Cholesterol; Clinical Trials as Topic; Clofibrate; Female; Hum

1976
[Treatment of primary hyperlipoproteinaemia types, IIa, IIb, 3 and IV with clofibrate (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1973, Dec-07, Volume: 98, Issue:49

    Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Ambulatory Care; Anticoagulants; Aspartate

1973
Colestipol and clofibrate in hypercholesterolemia.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Analysis of Variance; Anticholesteremic Agents; Blood Pressure; B

1974
Effects of a phenolic ether, Su-13437, on serum cholesterol, triglyceride, and transaminase levels of human subjects.
    Circulation, 1970, Volume: 42, Issue:5

    Topics: Adult; Aged; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Body Weigh

1970

Other Studies

157 other studies available for clofibrate and Body Weight

ArticleYear
Hypolipidemic analogues of ethyl 4-benzyloxybenzoate.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:11

    Topics: Animals; Benzoates; Body Weight; Cholesterol; Fatty Acids; Hypolipidemic Agents; Liver; Male; Organ

1977
Cycloalkanones. 8. Hypocholesterolemic activity of long-chain ketones related to pentadecanone.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:2

    Topics: Animals; Anticholesteremic Agents; Body Weight; Castration; Cell Membrane; Cholesterol; DNA; Eating;

1976
Hypocholesterolemic activity of 1,3-bis(substituted phenoxy)-2-propanones.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:2

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Depression, Chemical; DNA; Female; Fert

1976
Synthesis and biological evaluation of substituted 2,2'-oxybis(propionic acid) derivatives and related compounds.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:5

    Topics: Animals; Body Weight; Cholesterol; Depression, Chemical; Furans; Hypoglycemic Agents; Male; Morpholi

1976
Heterocyclic analogues of chlorcyclizine with potent hypolipidemic activity.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:10

    Topics: Animals; Body Weight; Chemical Phenomena; Chemistry; Cholesterol, Dietary; Eating; Hypolipidemic Age

1984
A new multifunctional hydroxytyrosol-clofibrate with hypolipidemic, antioxidant, and hepatoprotective effects.
    Bioorganic & medicinal chemistry letters, 2018, 10-01, Volume: 28, Issue:18

    Topics: Animals; Antioxidants; Body Weight; Clofibrate; Dose-Response Relationship, Drug; Hepatocytes; Hypol

2018
Acute kidney disease and acute kidney injury biomarkers in coronary care unit patients.
    BMC nephrology, 2020, 06-01, Volume: 21, Issue:1

    Topics: Acute Disease; Acute Kidney Injury; Age Factors; Aged; Biomarkers; Body Weight; Clofibrate; Coronary

2020
Repeated dose liver micronucleus assay using clofibrate in young adult rats.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 780-781

    Topics: Administration, Oral; Age Factors; Animals; Body Weight; Bone Marrow; Cell Division; Clofibrate; Com

2015
Up-regulation of Hnf1α gene expression in the liver of rats with experimentally induced chronic renal failure - A possible link between circulating PCSK9 and triacylglycerol concentrations.
    Atherosclerosis, 2016, Volume: 248

    Topics: Actins; Animals; Apolipoprotein B-100; Body Weight; Carrier Proteins; Clofibrate; Disease Models, An

2016
THE SEPARATE HYPOLIPOPROTEINEMIC EFFECTS OF DEXTROTHYROXINE AND ETHYL CHLOROPHENOXYISOBUTYRATE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Androsterone; Biomedical Research; Blood Chemical Analysis; Blood Proteins; Body Weight; Butyrates;

1964
A mouse model for alpha-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids.
    Human molecular genetics, 2004, May-01, Volume: 13, Issue:9

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bile Acids and Salts; Body Weight; Cholesterol; Cholesterol

2004
Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver.
    European journal of clinical investigation, 2004, Volume: 34, Issue:6

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Oxidase; Animals; Antioxidants; Body Weight; Clofibrate; Dietary Fa

2004
Clofibrate increases hepatic triiodothyronine (T3)- and thyroxine (T4)-glucuronosyltransferase activities and lowers plasma T3 and T4 concentrations in pigs.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:11

    Topics: Animals; Body Weight; Clofibrate; Gene Expression; Glucuronosyltransferase; Hypolipidemic Agents; Li

2006
Clofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Anticholesteremic Agents; Apolipoprotein A-I; Apolip

2007
Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats.
    American journal of hypertension, 2008, Volume: 21, Issue:3

    Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Clofibrate; Disease Models, Animal; Glucuron

2008
Clofibrate treatment up-regulates novel organic cation transporter (OCTN)-2 in tissues of pigs as a model of non-proliferating species.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: Animals; Betaine; Body Weight; Carnitine; Clofibrate; Eating; Enterocytes; gamma-Butyrobetaine Dioxy

2008
Glycogenolytic and hypolipidemic effect of clofibrate (CPIB) in the hypothyroid chick.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1980, Volume: 66, Issue:2

    Topics: Animals; Bile; Blood Glucose; Body Weight; Chickens; Clofibrate; Hypothyroidism; Kidney; Lipid Metab

1980
Effects of the hepatocarcinogenic peroxisome-proliferating hypolipidemic agents clofibrate and nafenopin on the rat liver cell membrane enzymes gamma-glutamyltranspeptidase and alkaline phosphatase and on the early stages of liver carcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: 2-Acetylaminofluorene; Alkaline Phosphatase; Animals; Body Weight; Cell Division; Cell Membrane; Clo

1984
Alterations in rat serum lipids and apolipoproteins following clofibrate treatment.
    Atherosclerosis, 1983, Volume: 49, Issue:3

    Topics: Animals; Apolipoprotein A-I; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins B; Apolipoprotei

1983
Consensus conference: Treatment of hypertriglyceridemia.
    JAMA, 1984, Mar-02, Volume: 251, Issue:9

    Topics: Body Weight; Cardiovascular Diseases; Clofibrate; Gemfibrozil; Humans; Hyperlipidemias; Hyperlipopro

1984
[Experimental induction of atherosclerosis in guinea pigs fed a cholesterol and vitamin D2-rich diet].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 81, Issue:4

    Topics: 4-Aminobenzoic Acid; Animals; Aorta; Arteriosclerosis; Body Weight; Calcium; Cholesterol; Clofibrate

1983
Cetaben versus clofibrate: comparison of toxicity and peroxisome proliferation in rats.
    Toxicology, 1983, Volume: 28, Issue:4

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Animals; Body Weight; Catalase; Clofibrate; Female; Hepatomegal

1983
Favorable effects of the lipid-lowering and platelet antiaggregant Plafibride on the aging process of mice of the C57bl/6J strain.
    Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:10

    Topics: Aging; Animal Feed; Animals; Body Weight; Clofibrate; Clofibric Acid; Hypolipidemic Agents; Lipofusc

1983
Aminophenyl ether compound (YM-95831), a new hypolipidemic agent with a high density lipoprotein elevating activity in rats.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:2

    Topics: Anilides; Animals; Body Weight; Cholesterol; Cholesterol, HDL; Clofibrate; Diet; Hypolipidemic Agent

1983
Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator.
    Cancer research, 1984, Volume: 44, Issue:3

    Topics: Animals; Anisoles; Antioxidants; Body Weight; Butylated Hydroxyanisole; Carcinogens; Clofibrate; Clo

1984
Effect of phenoxy acids on rat liver regeneration.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 43, Issue:2

    Topics: Animals; Body Weight; Carboxylic Acids; Clofibrate; Diet; Female; Hepatectomy; Liver; Liver Regenera

1984
Experimental atherosclerosis in hypercholesterolemic mini-pigs. Regression of cholesterol ester accumulation in aorta and coronary arteries after treatment with clofibrate, beta-pyridylcarbinol or a normo-lipidemic diet.
    Atherosclerosis, 1982, Volume: 45, Issue:2

    Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cholesterol; Cholesterol

1982
[Lipid lowering treatment and regression of arteriosclerosis (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Mar-28, Volume: 122, Issue:13

    Topics: Animals; Arteriosclerosis; Body Weight; Cholesterol; Cholesterol, Dietary; Clofibrate; Colestipol; C

1980
[Bezafibrate and delayed action etofibrate in hyperlipidemia].
    Deutsche medizinische Wochenschrift (1946), 1983, Feb-25, Volume: 108, Issue:8

    Topics: Bezafibrate; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Aci

1983
Clofibrate decreases jejunal cholesterol synthesis and activity of postheparin plasma lipoprotein lipase in the rat.
    Pharmacology, 1983, Volume: 26, Issue:5

    Topics: Animals; Body Weight; Cholesterol; Clofibrate; Diet; Intestinal Mucosa; Intestines; Jejunum; Lipopro

1983
Clofibrate and the development of rats.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 4

    Topics: Animals; Body Weight; Clofibrate; Female; Gestational Age; Growth; Liver; Organ Size; Pregnancy; Rat

1980
Dose-response study of the effect of ciprofibrate on serum lipoprotein concentrations in hyperlipoproteinaemia.
    Atherosclerosis, 1982, Volume: 42, Issue:2-3

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Sedimentation; Body Weight; Cholesterol; Ch

1982
Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters.
    Atherosclerosis, 1980, Volume: 37, Issue:2

    Topics: Adult; Apolipoproteins; Bezafibrate; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Clofibric

1980
Changes in glucose tolerance and plasma insulin during lipid-lowering treatment with diet, clofibrate and niceritrol.
    Atherosclerosis, 1982, Volume: 43, Issue:2-3

    Topics: Aged; Arteriosclerosis; Blood Glucose; Body Weight; Clofibrate; Dietary Carbohydrates; Female; Gluco

1982
Metabolic immunodepression and metabolic immunotherapy: an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances.
    Oncology, 1982, Volume: 39, Issue:1

    Topics: Age Factors; Body Weight; Breast Neoplasms; Clofibrate; Female; Hormones; Humans; Hypersensitivity,

1982
Effects of various concentrations of ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat.
    Carcinogenesis, 1982, Volume: 3, Issue:9

    Topics: Animals; Body Weight; Clofibrate; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship,

1982
Accumulation of adipocyte cholesterol during hypolipidemic drug treatment in cholesterol-fed rats.
    Biochimica et biophysica acta, 1982, Dec-13, Volume: 713, Issue:3

    Topics: Adipose Tissue; Animals; Body Weight; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Clofi

1982
Studies on the metabolism of unsaturated fatty acids. XI. Alterations in the activities of enoyl-CoA hydratase, 3-hydroxyacyl-CoA epimerase and 2,4-dienyl-CoA reductase in rat liver mitochondria and peroxisomes by clofibrate.
    Journal of biochemistry, 1982, Volume: 92, Issue:6

    Topics: Animals; Body Weight; Clofibrate; Enoyl-CoA Hydratase; Fatty Acid Desaturases; Hydro-Lyases; Isomera

1982
[Evaluation of the antilipaemic potential of etofylline clofibrate, its metabolites and clofibrate in dietary-induced hyperlipidaemia in the rat (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:11b

    Topics: Animals; Body Weight; Clofibrate; Diet; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Rats

1980
Toxicological studies of plafibride. Part 2: Subacute and subchronic toxicity in rats and chronic toxicity in dogs.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a

    Topics: Animals; Blood Cell Count; Body Weight; Clofibrate; Clofibric Acid; Dogs; Female; Male; Organ Size;

1981
[Effect of bezafibrate on the carbohydrate metabolism of 17 diabetics with hyperlipidemia].
    Die Medizinische Welt, 1981, Feb-20, Volume: 32, Issue:8

    Topics: Anticholesteremic Agents; Bezafibrate; Body Weight; Carbohydrate Metabolism; Clofibrate; Clofibric A

1981
Clinical experience with bezafibrate.
    Artery, 1980, Volume: 8, Issue:6

    Topics: Bezafibrate; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Clofibric Acid; Coronary Disease;

1980
[Hyperlipoproteinemias: experience of out-patient treatment of 112 patients (author's transl)].
    Revista medica de Chile, 1981, Volume: 109, Issue:10

    Topics: Body Weight; Cholesterol; Cholestyramine Resin; Clofibrate; Humans; Hyperlipoproteinemias; Hypolipid

1981
The concentration of high density lipoprotein in patients with type IV hyperlipoproteinemia and the effect of clofibrate.
    Atherosclerosis, 1980, Volume: 36, Issue:4

    Topics: Adult; Body Weight; Cholesterol; Clofibrate; Humans; Hyperlipoproteinemia Type IV; Lipoproteins, HDL

1980
Effect of probucol on cholesterol metabolism in the rat.
    Atherosclerosis, 1980, Volume: 36, Issue:4

    Topics: Animals; Body Weight; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Hydroxymethylglutary

1980
[Comparative study of the effects of probucol, fenofibrate and clofibrate on liver ultrastructure in rats (author's transl)].
    La Nouvelle presse medicale, 1980, Oct-30, Volume: 9, Issue:40

    Topics: Animals; Body Weight; Clofibrate; Fenofibrate; Hypolipidemic Agents; Lipids; Liver; Microbodies; Mic

1980
The effects of probucol and clofibrate alone and in combination on hepatic cholesterol metabolism in the male rat.
    Biochimica et biophysica acta, 1995, Mar-16, Volume: 1255, Issue:2

    Topics: Animals; Body Weight; Cholesterol; Clofibrate; Cytosol; Lipid Metabolism; Lipids; Liver; Male; Micro

1995
In vitro glucuronidation of peroxisomal proliferators: 2-ethylhexanoic acid enantiomers and their structural analogs.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:2

    Topics: Animals; Body Weight; Caproates; Chromatography, High Pressure Liquid; Clofibrate; Glucuronates; Glu

1995
The effects of clofibrate and bezafibrate on cholesterol metabolism in the liver of the male rat.
    Lipids, 1994, Volume: 29, Issue:11

    Topics: Animals; Bezafibrate; Body Weight; Cholesterol; Cholesterol Esters; Clofibrate; Cytosol; Liver; Male

1994
Pyruvate inhibits clofibrate-induced hepatic peroxisomal proliferation and free radical production in rats.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:2

    Topics: Animals; Body Weight; Catalase; Clofibrate; Diet; Drug Interactions; Free Radicals; Lipofuscin; Live

1995
Effects of chronic administration of the peroxisome proliferator, clofibrate, on cytosolic acetyl-CoA hydrolase in rat liver.
    Biochemical pharmacology, 1993, Apr-06, Volume: 45, Issue:7

    Topics: Acetyl-CoA Hydrolase; Animals; Biomarkers; Body Weight; Clofibrate; Cytosol; Diet; Enzyme Induction;

1993
Interactive potential of omega-3 fatty acids with clofibrate or DEHP on hepatic peroxisome proliferation in male Wistar rats.
    Human & experimental toxicology, 1993, Volume: 12, Issue:4

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Oxidase; Animals; Body Weight; Cell Division; Clofibrate;

1993
Change of the sex-dependent response to clofibrate in F344 rat liver during postnatal development.
    Toxicology letters, 1996, Volume: 85, Issue:2

    Topics: Administration, Oral; Aging; Animals; Body Weight; Cholesterol; Clofibrate; Cytochrome P-450 Enzyme

1996
Translactational induction of CYP4A expression in 10.5-day neonatal rats by the hypolipidemic drug clofibrate.
    Biochemical pharmacology, 1995, Dec-22, Volume: 50, Issue:12

    Topics: Animals; Animals, Newborn; Animals, Suckling; Base Sequence; Blotting, Northern; Blotting, Western;

1995
A glucose-regulated protein, GRP58, is down-regulated in C57B6 mouse liver after diethylhexyl phthalate exposure.
    Toxicology and applied pharmacology, 1998, Volume: 148, Issue:1

    Topics: Animals; Base Sequence; Body Weight; Clofibrate; Diethylhexyl Phthalate; DNA Primers; DNA, Complemen

1998
Differential effects of nongenotoxic and genotoxic carcinogens on the preneoplastic lesions in the rat liver.
    Archives of pharmacal research, 1998, Volume: 21, Issue:4

    Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Cell Count; Clofibrate; Diethylnitrosamine;

1998
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.
    The Journal of toxicological sciences, 1999, Volume: 24, Issue:3

    Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinoma, Hepatocellular; Clofibrate; Cocarcinogenesis;

1999
Effect of peroxisome proliferator on extracellular glutathione peroxidase in rat.
    Free radical research, 1999, Volume: 31, Issue:3

    Topics: Aldehydes; Animals; Blotting, Northern; Body Weight; Catalase; Clofibrate; Diethylhexyl Phthalate; E

1999
The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat.
    Archives of toxicology, 1999, Volume: 73, Issue:7

    Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Clofibrate; Connexins; Cytochrome P-450 En

1999
Investigation of the potential of conjugated linoleic acid (Cla) to cause peroxisome proliferation in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:11

    Topics: Animals; Body Weight; Carnitine O-Acetyltransferase; Clofibrate; Cytochrome P-450 Enzyme System; Dri

1999
Caloric restriction prevents oxidative damage induced by the carcinogen clofibrate in mouse liver.
    FEBS letters, 2000, May-04, Volume: 473, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acyl-CoA Oxidase; Animals; Body Weight; Carcinogens; Cell Nucleus; Clof

2000
Effects of di-isononyl phthalate, di-2-ethylhexyl phthalate, and clofibrate in cynomolgus monkeys.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 56, Issue:1

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Body Weight; Cell Communication; Clofibrate

2000
Peroxisome proliferator-activated receptor alpha (PPAR alpha) agonist, WY-14,643, increased transcription of myosin light chain-2 in cardiomyocytes.
    The Journal of toxicological sciences, 2001, Volume: 26, Issue:5

    Topics: Animals; Body Weight; Cardiac Myosins; Cell Line; Clofibrate; Diethylhexyl Phthalate; Dose-Response

2001
Effect of clofibrate on lipid metabolism in streptozotocin diabetic rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 148, Issue:3

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Diabetes Mellitus; Eat

1975
Effect of citrate and aminotriazole on matrical plates induced in hepatic microbodies.
    Virchows Archiv. B, Cell pathology, 1975, Volume: 17, Issue:4

    Topics: Amitrole; Animals; Aspirin; Body Weight; Carboxylic Acids; Catalase; Citrates; Clofibrate; Cycloprop

1975
Should hyperlipoproteinemia be treated in patients with coronary artery disease?
    JAMA, 1975, Jul-21, Volume: 233, Issue:3

    Topics: Adolescent; Adult; Aged; Arteriosclerosis; Body Weight; Cholestyramine Resin; Clofibrate; Coronary D

1975
Experimental and clinical evaluation of two "Atromid-S" analogues in relation to their differential modes of action.
    Advances in experimental medicine and biology, 1975, Volume: 63

    Topics: Animals; Body Weight; Butyrates; Clofenapate; Clofibrate; Diabetes Mellitus; Fatty Acids, Nonesterif

1975
[Effect of clofibrate on glucose tolerance and insulin secretion in patients with endogenous hypertriglyceridemia (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Mar-19, Volume: 118, Issue:12

    Topics: Administration, Oral; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Glucose; Glucose Toleranc

1976
Effects of ethyl p-chlorophenoxyisobutyrate on carbohydrate and fatty acid metabolism in rat liver.
    Journal of biochemistry, 1975, Volume: 78, Issue:6

    Topics: Animals; Body Weight; Carbohydrate Metabolism; Cholesterol; Clofibrate; Cytoplasm; Diet; Fatty Acids

1975
Dietary and drug treatment of hyperlipidaemia. A feasibility study in asymptomatic middle-aged men.
    Upsala journal of medical sciences, 1976, Volume: 81, Issue:2

    Topics: Body Weight; Cholesterol; Clofibrate; Follow-Up Studies; Humans; Hypercholesterolemia; Hyperlipidemi

1976
Pharmacokinetics of clofibrate in familial hypercholesterolemia.
    Atherosclerosis, 1977, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Body Weight; Cholesterol; Clofibrate; Dose-Response Relationship, Drug; Drug Resi

1977
Effect of clofibrate treatment on chronic hyperlipidemia induced by an ACTH-producing tumor.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Cholesterol; Clofibrate; Growth Hormone; Hyperlip

1977
Lecithin:cholesterol acyl transfer rate and high density lipoproteins in plasma during dietary and clofibrate treatment of hypertriglyceridemic subjects.
    Atherosclerosis, 1978, Volume: 31, Issue:1

    Topics: Body Weight; Clofibrate; Humans; Hyperlipidemias; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Ac

1978
Experimental porphyria induced by 3-(2,4,6-trimethylphenyl)-thioethyl)-4 methylsydnone.
    Virchows Archiv. B, Cell pathology, 1975, Volume: 18, Issue:2

    Topics: Alcohol Oxidoreductases; Animals; Bile Ducts, Intrahepatic; Body Weight; Catalase; Chemical and Drug

1975
Effect of clofibrate on cholesterol and DNA synthesis in rat ventral prostate.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 160, Issue:4

    Topics: Animals; Body Weight; Castration; Cholesterol; Clofibrate; Depression, Chemical; DNA; Liver; Male; O

1979
Hyperlipoproteinemia induced by a transplantable pituitary tumor in the rat.
    Atherosclerosis, 1979, Volume: 32, Issue:1

    Topics: Animals; Body Weight; Cholesterol; Clofibrate; Electrophoresis, Agar Gel; Electrophoresis, Polyacryl

1979
Effect of clofibrate and gemfibrozil on the activities of mitochondrial carnitine acyltransferases in rat liver. Dose--response relations.
    Atherosclerosis, 1979, Volume: 32, Issue:1

    Topics: Acyltransferases; Animals; Body Weight; Carnitine Acyltransferases; Clofibrate; Dose-Response Relati

1979
Action of tiadenol and clofibrate on biliary excretions of cholesterol and bile salts in rats.
    Digestion, 1979, Volume: 19, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Body Weight; Cholesterol; Clofibrate; Fatty Alcohols; Hypolipid

1979
The effect of clofibrate on heart and plasma lipids in rats fed a diet containing rapeseed oil.
    Lipids, 1979, Volume: 14, Issue:7

    Topics: Animals; Arachis; Body Weight; Brassica; Clofibrate; Dietary Fats; Fatty Acids; Lipid Metabolism; Li

1979
Bile formation and biliary lipid composition under the influence of clofibrate and phenobarbital pretreatment in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 308, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Body Weight; Cholesterol; Clofibrate; Lipid Metabolism; Liver;

1979
Treatment of hyperlipoproteinemia type II with etofibrate.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:12

    Topics: Body Weight; Cholesterol; Clofibrate; Clofibric Acid; Glucose Tolerance Test; Humans; Hyperlipoprote

1979
Effect of clofibrate administration on metabolic changes in the starving rat.
    Indian journal of biochemistry & biophysics, 1979, Volume: 16, Issue:6

    Topics: Animals; Body Weight; Clofibrate; Liver; Male; Organ Size; Rats; Starvation

1979
Animal models for screening hypolipidemic agents. I. Response to clofibrate in NMRI-mice of different body-weights.
    Zeitschrift fur Versuchstierkunde, 1978, Volume: 20, Issue:1

    Topics: Animals; Body Weight; Clofibrate; Disease Models, Animal; Drug Evaluation, Preclinical; Hyperlipidem

1978
Fundamental studies on physiological and pharmacological actions of L-ascorbate 2-sulfate. V. On the hypolipidemic and antiatherosclerotic effects of L-ascorbate 2-sulfate in rabbits.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:1

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Ascorbic Acid; Body Weight; Cholesterol; Clofibrate; Hyp

1978
Maternal transport of chlorophenoxyisobutyrate at the foetal and neonatal stages of development.
    Biochemical pharmacology, 1978, Volume: 27, Issue:16

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Clofibrate; Female; Fetus; In Vitro Techniques; Liver

1978
Comparison of hypocholesterolemic activity for cyclic analogs of clofibrate in normolipemic rats.
    Atherosclerosis, 1977, Volume: 27, Issue:1

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Clofibrate; Glucose Oxidase; Male; Micr

1977
The effects of tiadenol, clofibrate and clofibride on bile composition in the rat.
    European journal of pharmacology, 1977, May-01, Volume: 43, Issue:1

    Topics: Amides; Animals; Bile; Bile Acids and Salts; Body Weight; Cholesterol; Clofibrate; Fatty Alcohols; H

1977
Hypocholesterolaemia in the rat after p-chlorophenoxyisobutyric acid (CPIB) administration as a synthetic triglyceride, 1,3-dipalmitoyl 2(p-chlorophenoxyisobutyroyl)-rac-glycerol.
    Clinica chimica acta; international journal of clinical chemistry, 1977, Sep-01, Volume: 79, Issue:2

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Clofibrate; Lipid Metabolism; Lipids; L

1977
Differential increase of hepatic peroxisomal, mitochondrial and microsomal carnitine acyltransferases in clofibrate-fed rats.
    Biochemical pharmacology, 1977, Sep-15, Volume: 26, Issue:18

    Topics: Acyltransferases; Animals; Body Weight; Carnitine Acyltransferases; Centrifugation, Density Gradient

1977
Pharmacokinetics of drugs in patients with the nephrotic syndrome.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:6

    Topics: Adult; Antipyrine; Blood Proteins; Body Weight; Clofibrate; Dose-Response Relationship, Drug; Female

1975
Lack of effect of cholestyramine on the pharmacokinetics of clofibrate in man.
    European journal of clinical investigation, 1975, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Bile; Body Weight; Cholestyramine Resin; Clofibrate; Drug Interactions; Fec

1975
Effect of ascofuranone on serum lipids of rats fed a cholesterol rich diet.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Proteins; Body Weight; Cholesterol

1975
Efficacy and interactions of oxandrolone, halo-fenate and clofibrate in a factorial study on experimental acute nephrotic hyperlipidemia.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:1

    Topics: Animals; Body Weight; Butyrates; Cholesterol; Clofibrate; Dose-Response Relationship, Drug; Drug Eva

1975
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
    Voprosy onkologii, 1975, Volume: 21, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C

1975
[Letter: Treatment in hypercholestermia].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jan-10, Volume: 96, Issue:1

    Topics: Adult; Body Weight; Clofibrate; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Smoking

1976
The involvement of selenium in peroxisome proliferation caused by dietary administration of clofibrate to rats.
    Chemico-biological interactions, 1992, Nov-30, Volume: 85, Issue:1

    Topics: Animals; Body Weight; Cells, Cultured; Clofibrate; Diet; Glutathione Peroxidase; Glutathione Transfe

1992
Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by hypolipidemic peroxisome proliferators.
    Biochimica et biophysica acta, 1992, Apr-30, Volume: 1135, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bezafibrate; Body Weight; Calmodulin; Catala

1992
Effects of clofibrate on basal and insulin-activated glucose uptake in fast and slow skeletal muscles of rats.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:1-2

    Topics: Animals; Body Weight; Clofibrate; Glucose; Insulin; Male; Muscles; Organ Size; Rats; Rats, Inbred St

1991
Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Animals; Body Weight; Carcinogens; Cell Survival; Clofibrate; Cyproterone; Cyproterone Acetate; Fema

1990
Stereochemical selectivity in the induction of cytochrome P450IVA1 (P452)-dependent fatty acid hydroxylation and peroxisome proliferation.
    Biochemical pharmacology, 1991, Mar-01, Volume: 41, Issue:5

    Topics: Animals; Body Weight; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Fatty Acids; Hyd

1991
Effect of simvastatin (MK-733) on plasma triacylglycerol levels in rats.
    Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8

    Topics: Adipose Tissue; Animals; Body Weight; Clofibrate; Energy Intake; Lipoprotein Lipase; Lipoproteins; L

1991
Enhancement of NAD-linked isocitrate dehydrogenase activity in rat liver by clofibrate feeding.
    Biochemical pharmacology, 1991, Jun-01, Volume: 41, Issue:11

    Topics: Animals; Body Weight; Clofibrate; Diet; Isocitrate Dehydrogenase; Liver; Male; Mitochondria, Liver;

1991
Atherosclerosis mouse model induced by a high-cholesterol diet supplemented with beta-aminopropionitrile: effects of various anti-atherosclerotic agents on the biochemical parameters.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:2

    Topics: 4-Aminobenzoic Acid; Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol;

1990
Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:12

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Clofibrate; Diethylhexyl Phthalate;

1990
Toxicological studies on a benzofurane derivative. II. Demonstration of peroxisome proliferation in rat liver.
    Toxicology and applied pharmacology, 1990, Volume: 106, Issue:3

    Topics: Animals; Benzbromarone; Body Weight; Clofibrate; Liver; Male; Microbodies; Microscopy, Electron; Org

1990
Induction of peroxisome proliferation in rainbow trout exposed to ciprofibrate.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Acyl-CoA Oxidase; Analysis of Variance; Animals; Blotting, Western; Body Weight; Catalase; Clofibrat

1990
Effect of the peroxisome proliferator ciprofibrate on hepatic DNA synthesis and hepatic composition following partial hepatectomy in rats.
    Toxicology, 1990, Volume: 62, Issue:3

    Topics: Administration, Oral; Animals; Body Weight; Clofibrate; Clofibric Acid; DNA; Female; Fibric Acids; H

1990
Characterization of the hepatic responses to the short-term administration of ciprofibrate in several rat strain. Co-induction of microsomal cytochrome P-450 IVA1 and peroxisome proliferation.
    Biochemical pharmacology, 1990, Sep-01, Volume: 40, Issue:5

    Topics: Administration, Oral; Animals; Body Weight; Cell Division; Clofibrate; Clofibric Acid; Cytochrome P-

1990
In vivo and in vitro peroxisome proliferation properties of selected clofibrate analogues in the rat. Structure-activity relationships.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Acyl-CoA Oxidase; Animals; Body Weight; Cell Division; Choleste

1990
Comparison of dehydroepiandrosterone and clofibric acid treatments in obese Zucker rats.
    The Journal of nutrition, 1989, Volume: 119, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Clofibrate; Clofibric Acid; Dehydroepiandrosterone; Disease Mod

1989
Modulation of diethylnitrosamine-initiated placental glutathione S-transferase positive preneoplastic and neoplastic lesions by clofibrate, a hepatic peroxisome proliferator.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Animals; Body Weight; Clofibrate; Diethylnitrosamine; Female; Glutathione Transferase; Immunoenzyme

1989
Teratological study of the hypolipidaemic drugs etofylline clofibrate (VULM) and fenofibrate in Swiss mice.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:3

    Topics: Animals; Body Weight; Clofibrate; Female; Fenofibrate; Fetus; Gestational Age; Hypolipidemic Agents;

1989
Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:3

    Topics: Animals; Body Weight; Clofibrate; Diethylnitrosamine; gamma-Glutamyltransferase; Glucosephosphate De

1986
Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:4

    Topics: Animals; Biphenyl Compounds; Body Weight; Butyrophenones; Clofibrate; Clofibric Acid; Cytochrome P-4

1987
The effect of feeding fish oils, vegetable oils and clofibrate on the ketogenesis from long chain fatty acids in hepatocytes.
    Lipids, 1986, Volume: 21, Issue:8

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Body Weight; Carbon Radioisotopes; Clofibrate; Fatty A

1986
Epoxide-metabolizing enzymes in mammary gland and liver from BALB/c mice and effects of inducers on enzyme activity.
    Cancer research, 1988, Mar-15, Volume: 48, Issue:6

    Topics: Animals; Body Weight; Chromatography, Affinity; Clofibrate; Enzyme Induction; Enzyme-Linked Immunoso

1988
Peroxisomal beta-oxidation and catalase activities in fetal rat liver: effect of maternal treatment with clofibrate.
    Cellular and molecular biology, 1988, Volume: 34, Issue:2

    Topics: Animals; Body Weight; Catalase; Clofibrate; Female; Liver; Maternal-Fetal Exchange; Microbodies; Org

1988
Hypocholesterolemic activity of racemic dichlorophenoxypropionic acid or its enantiomers in rats.
    Bulletin of environmental contamination and toxicology, 1987, Volume: 39, Issue:6

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Clofibr

1987
Effect of pollen extract on the development of experimental atherosclerosis in rabbits.
    Atherosclerosis, 1986, Volume: 62, Issue:1

    Topics: Animals; Arteriosclerosis; Body Weight; Cholesterol, Dietary; Cholesterol, HDL; Clofibrate; Diet, At

1986
The effect of three hypolipidemic drugs on catalase activity and peroxisomal and mitochondrial palmitate oxidation in rat cardiac and skeletal muscle.
    Biochimica et biophysica acta, 1986, Feb-19, Volume: 880, Issue:2-3

    Topics: Animals; Body Weight; Catalase; Clofibrate; Clofibric Acid; Fibric Acids; Hypolipidemic Agents; Male

1986
Effect of clofibrate and colestipol singly and in combination on plasma lipids and lipoproteins in type III hyperlipoproteinemia.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:10

    Topics: Adult; Body Weight; Cholesterol; Clofibrate; Colestipol; Drug Therapy, Combination; Humans; Hyperlip

1985
Metabolic relationships among the plasma lipoproteins. Reciprocal changes in the concentrations of very low and low density lipoproteins in man.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Angina Pectoris; Body Weight; Cholesterol; Clofibrate; Coronary Disease; Female;

1972
Pharmacological study of hydroxy bis-[2-(p-chlorophenoxy)-isobutyric acid] aluminium. II. The effect of hydroxy bis-[2-(-chlorophenoxy)-isobutyric acid] aluminum on lipid metabolism in hypercholesterolimic rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Adipose Tissue; Animals; Anticholesteremic Agents; Body Weight; Brain; Cholesterol; Cholesterol, Die

1973
Hyperlipoproteinemia. Some basic concepts on diagnosis and management.
    JAMA, 1973, Nov-05, Volume: 226, Issue:6

    Topics: Adult; Age Factors; Aged; Aminosalicylic Acids; Blood Protein Disorders; Body Weight; Cholesterol; C

1973
A kinetic comparison of the physiological effects of clofibrate and clofenapate in the rat.
    Environmental physiology & biochemistry, 1974, Volume: 4, Issue:2

    Topics: Animals; Body Weight; Butyrates; Catalase; Cell Nucleus; Cholesterol; Clofenapate; Clofibrate; Depre

1974
[Lipid depression by etofibrate in a comparative study in rats with artificial hyperlipidemia].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Body Weight; Cholesterol; Clofibrate; Depressio

1974
Pharmacological study of hydroxy bis-[2-(p-chlorophenoxy)-isobutyric acid] aluminium. I. The effect of hydroxy bis-[2-(p-chlorophenoxy)-isobutyric acid] aluminum on lipid metabolism in normal rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Aluminum; Animals; Anticholesteremic Agents; Body Weight; Butyrates; Cholesterol; Clofibrate; Fatty

1973
Studies of primary hyperlipoproteinemias. IV. Treatment.
    Polish medical journal, 1972, Volume: 11, Issue:5

    Topics: Adult; Blood Protein Disorders; Body Weight; Cholesterol; Clofibrate; Diet Therapy; Humans; Lipoprot

1972
[Clinical and epidemiological aspects of human glyceridemia. IV. Etiological diagnosis and treatment of hyperglyceridemia. Practical aspects].
    Bruxelles medical, 1972, Volume: 52, Issue:12

    Topics: Alcohol Drinking; Body Weight; Clofibrate; Diet; Dietary Carbohydrates; Electrophoresis, Starch Gel;

1972
Growth hormone secretion in primary endogenous hypertriglyceridemia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1973, Volume: 5, Issue:3

    Topics: Adult; Arginine; Blood Glucose; Body Weight; Clofibrate; Fatty Acids, Nonesterified; Female; Glucago

1973
[Does magnesium-orotate improve the effect of lipid lowering drugs?].
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 8, Issue:1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Body Weight; Cholesterol; Clofibra

1973
The effects of colestipol resin and of colestipol plus clofibrate on the turnover of plasma cholesterol in man.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:10

    Topics: Adult; Anticholesteremic Agents; Body Weight; Carbon Isotopes; Cholesterol; Clofibrate; Drug Synergi

1973
Effect of SaH 42-348, an analog of clofibrate, on lipid metabolism in rats.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:6

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Cholesterol, Dietary; Clofibrate; Diet,

1973
Editorial: Diet and drugs for hyperlipidaemia.
    Drugs, 1973, Volume: 6, Issue:1

    Topics: Body Height; Body Weight; Clofibrate; Diet; Humans; Hyperlipidemias; Patient Care Planning; Vascular

1973
[Hyperlipoproteinemia type 3. Report on 5 cases].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:5

    Topics: Adult; Blood Protein Electrophoresis; Body Weight; Cholesterol; Clofibrate; Diagnosis, Differential;

1973
The effect of ethyl-alpha-p-chlorophenoxisobutyrate (clofibrate) on alcohol metabolism.
    Life sciences, 1973, Oct-01, Volume: 13, Issue:7

    Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Body Weight; Carbon Radioisotopes; Catalase;

1973
Treatment of type II and type IV Fredrickson's hyperlipoproteinemia.
    Advances in experimental medicine and biology, 1973, Volume: 38

    Topics: Adolescent; Adult; Alcohol Drinking; Body Weight; Child; Cholesterol, Dietary; Cholestyramine Resin;

1973
Potential hypolipidemic agents. 7. Synthesis and lipid-lowering properties of 2-(dibenzofuranyloxy)-2-methylpropionates and related compounds.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:1

    Topics: Animals; Benzofurans; Body Weight; Butyrates; Cholesterol; Clofibrate; Hypolipidemic Agents; Male; M

1974
Differential effects of benzodioxane, chroman, and dihydrobenzofuran analogs of clofibrate on various parameters of hepatic drug metabolism.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:1

    Topics: Aniline Compounds; Animals; Benzofurans; Benzopyrans; Body Weight; Clofibrate; Cytochrome P-450 Enzy

1974
Effect of clofibrate on plasma glucose and serum immunoreactive insulin in patients with hyperlipoproteinemia.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:1

    Topics: Adult; Aged; Antigens; Blood Glucose; Blood Protein Disorders; Body Weight; Clofibrate; Fatty Acids,

1974
Structure of hepatic microbodies in rats treated with acetylsalicylic acid, clofibrate, and dimethrin.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 30, Issue:1

    Topics: Animals; Aspirin; Benzyl Compounds; Body Weight; Carboxylic Acids; Cholesterol; Chrysanthemum cinera

1974
Potential hypolipidemic agents. IX. Heterocyclic compouns related to methyl clofenapate.
    Acta pharmaceutica Suecica, 1974, Volume: 11, Issue:3

    Topics: Animals; Appetite; Body Weight; Chemical Phenomena; Chemistry; Cholesterol; Clofibrate; Depression,

1974
Potential hypolipidemic agents. 8. 2-Chloro-5-piperidinosulphono-3-thiophenecarboxylic acids.
    Acta pharmaceutica Suecica, 1974, Volume: 11, Issue:3

    Topics: Animals; Body Weight; Carboxylic Acids; Cholesterol; Clofibrate; Depression, Chemical; Drug Evaluati

1974
Restraint of cholesterol accumulation in tissue pools associated with drastic short-term lowering of serum cholesterol levels by clofibrate or cholestyramine in hypercholesterolemic swine.
    Journal of lipid research, 1974, Volume: 15, Issue:4

    Topics: Animals; Bile Acids and Salts; Body Weight; Carbon Radioisotopes; Cholesterol; Cholesterol, Dietary;

1974
Long-term treatment of hyperlipidemic patients with clofibrate.
    JAMA, 1971, Nov-15, Volume: 218, Issue:7

    Topics: Adult; Aged; Body Weight; Cholesterol; Clofibrate; Female; Glucose; Glucose Tolerance Test; Humans;

1971
[Classification of hyperlipoproteinaemia in primary gout].
    Deutsche medizinische Wochenschrift (1946), 1972, Apr-14, Volume: 97, Issue:15

    Topics: Adult; Aged; Arteriosclerosis; Blood Protein Disorders; Body Weight; Carbohydrate Metabolism; Clofib

1972
Serum lipid precursors of coronary heart disease.
    Human pathology, 1971, Volume: 2, Issue:1

    Topics: Adult; Aged; Arteriosclerosis; Blood Protein Disorders; Body Weight; Cholesterol; Cholestyramine Res

1971
Influence of obesity on the relationship between insulin and triglyceride levels in endogenous hypertriglyceridemia.
    Diabetes, 1971, Volume: 20, Issue:10

    Topics: Adult; Blood Glucose; Body Weight; Clofibrate; Dietary Carbohydrates; Fatty Acids, Nonesterified; Gl

1971
Induced alterations in composition of bile of persons having cholelithiasis.
    Gastroenterology, 1971, Volume: 61, Issue:4

    Topics: Bile; Bile Acids and Salts; Body Weight; Cholecystokinin; Cholelithiasis; Cholesterol; Cholestyramin

1971
Treatment of familial hypercholesterolemia in children.
    American heart journal, 1971, Volume: 82, Issue:5

    Topics: Adolescent; Arteriosclerosis; Body Weight; Child; Child, Preschool; Cholesterol; Clofibrate; Diet Th

1971
[Antilipidemic agents].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 5, Issue:3

    Topics: Adult; Alcohols; Anticholesteremic Agents; Biguanides; Blood Protein Disorders; Body Weight; Cholest

1971
A long-time study of the blood lipids of two students of atherosclerosis.
    Circulation, 1969, Volume: 40, Issue:6

    Topics: Age Factors; Aged; Arteriosclerosis; Body Weight; Cholesterol; Clofibrate; Coronary Disease; Diet; D

1969
Lipid lowering influence of ethyl p-chlorophenoxyisobutyrate in liver of rats fed high fat diets.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:2

    Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Clofibrate; Depre

1970
Treatment of the hyperlipidemic states with special emphasis on the place of cholestyramine in therapy.
    Angiology, 1970, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Aged; Body Weight; Child; Cholesterol; Cholestyramine Resin; Clofibrate; Dextroth

1970
Effect of atromid-S and high fat diet on lipid contents and lipolysis in rat tissues and serum.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 190, Issue:1

    Topics: Anticholesteremic Agents; Body Weight; Cholesterol; Clofibrate; Dietary Fats; Hypercholesterolemia;

1971
Ultracentrifugal demonstration of floating beta lipoproteins in type 3 hyperlipoproteinemia. Diagnostic value.
    Annals of internal medicine, 1971, Volume: 75, Issue:2

    Topics: Angina Pectoris; Blood Protein Disorders; Blood Protein Electrophoresis; Body Weight; Cholesterol; C

1971
Diet and drug therapy for hyperlipoproteinemia.
    Medical times, 1971, Volume: 99, Issue:8

    Topics: Anticholesteremic Agents; Body Weight; Cholestyramine Resin; Clofibrate; Diet Therapy; Dietary Carbo

1971