clofibrate has been researched along with Aortic Coarctation in 2 studies
angiokapsul: contains clofibrate & insoitolnicotinate
Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, our aim was to study whether clofibrate-induced peroxisome proliferator-activated receptor-alpha (PPAR-α) stimulation is able to prevent alterations in cardiac functioning derived from RAS overstimulation in the left ventricle of rats with hypertension secondary to aortic coarctation and to improve antioxidant defenses." | 3.83 | Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle. ( Cervantes-Pérez, LG; Del Valle-Mondragón, L; Ibarra-Lara, L; Oidor-Chan, VH; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Aguilar, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC; Zarco-Olvera, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibarra-Lara, L | 2 |
| Del Valle-Mondragón, L | 1 |
| Soria-Castro, E | 2 |
| Torres-Narváez, JC | 1 |
| Pérez-Severiano, F | 2 |
| Sánchez-Aguilar, M | 2 |
| Ramírez-Ortega, M | 1 |
| Cervantes-Pérez, LG | 2 |
| Pastelín-Hernández, GS | 2 |
| Oidor-Chan, VH | 1 |
| Zarco-Olvera, G | 1 |
| Sánchez-Mendoza, A | 2 |
| Del Valle, L | 1 |
| Rubio-Ruíz, E | 1 |
| Martínez-Lazcano, JC | 1 |
2 other studies available for clofibrate and Aortic Coarctation
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Aortic Coarct | 2016 |
PPARalpha stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner.
Topics: Angiotensin II; Animals; Antioxidants; Aortic Coarctation; Blood Pressure; Clofibrate; Gene Expressi | 2010 |