Page last updated: 2024-10-25

clofibrate and Adverse Drug Event

clofibrate has been researched along with Adverse Drug Event in 13 studies

angiokapsul: contains clofibrate & insoitolnicotinate

Research Excerpts

ExcerptRelevanceReference
" A proof of concept extension of the MOA framework is proposed for scoring confidence in the supporting data to improve scientific justification for MOA use in characterizing hazards and selecting dose-response extrapolation methods for specific chemicals."1.46Quantitative weight of evidence to assess confidence in potential modes of action. ( Becker, RA; Dellarco, V; Dourson, M; Foreman, J; Kirman, C; Kronenberg, JM; Linkov, I; Manibusan, MK; Meek, B; Palermo, C; Pottenger, LH; Schoeny, R; Seed, J, 2017)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M1
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W2
Ding, D1
Kelly, R1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Becker, RA1
Dellarco, V1
Seed, J1
Kronenberg, JM1
Meek, B1
Foreman, J1
Palermo, C1
Kirman, C1
Linkov, I1
Schoeny, R1
Dourson, M1
Pottenger, LH1
Manibusan, MK1
Dokianakis, SN1
Kornaros, ME1
Lyberatos, G1
Begemann, H1
Cunningham, MJ1
Liang, S1
Fuhrman, S1
Seilhamer, JJ1
Somogyi, R1
Dry, J1
Pradalier, A1
Saheta, NP1
Eipe, J1
Moses, AM1
Miller, M1

Reviews

4 reviews available for clofibrate and Adverse Drug Event

ArticleYear
[Therapeutics in 1978].
    La Revue du praticien, 1978, Sep-21, Volume: 28, Issue:41

    Topics: Amenorrhea; Anticholesteremic Agents; Artificial Organs; Biliary Tract Diseases; Bromocriptine; Chol

1978
Iatrogenic cardiovascular disease (an aspect of preventive cardiology).
    Indian heart journal, 1968, Volume: 20, Issue:4

    Topics: Abnormalities, Drug-Induced; Analgesics; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antidepressi

1968
Drugs affecting therapy with anticoagulants.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Intera

1972
Drug-induced dilutional hyponatremia.
    The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23

    Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate

1974

Other Studies

9 other studies available for clofibrate and Adverse Drug Event

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Quantitative weight of evidence to assess confidence in potential modes of action.
    Regulatory toxicology and pharmacology : RTP, 2017, Volume: 86

    Topics: Carcinogens; Chemical Safety; Clofibrate; Drug-Related Side Effects and Adverse Reactions; Humans; M

2017
On the effect of pharmaceuticals on bacterial nitrite oxidation.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2004, Volume: 50, Issue:5

    Topics: Bacteria, Anaerobic; Biodegradation, Environmental; Bioreactors; Carbamazepine; Cities; Clofibrate;

2004
[Hazardous ventures with medications].
    Therapie der Gegenwart, 1981, Volume: 120, Issue:10

    Topics: Chloramphenicol; Clofibrate; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical

1981
Gene expression microarray data analysis for toxicology profiling.
    Annals of the New York Academy of Sciences, 2000, Volume: 919

    Topics: Acetaminophen; Animals; Benzo(a)pyrene; Clofibrate; Drug-Related Side Effects and Adverse Reactions;

2000
When a drug is the culprit.
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect

1973