Page last updated: 2024-10-25

clofazimine and Uveitis, Anterior

clofazimine has been researched along with Uveitis, Anterior in 2 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Uveitis, Anterior: Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation into the anterior chamber, iris changes, and adhesions between the iris and lens (posterior synechiae). Intraocular pressure may be increased or reduced.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Duran Merino, CE1
Ortiz Úsuga, MC1
Jaramillo, MJ1
Rodríguez, AM1
Ramu, G1

Reviews

1 review available for clofazimine and Uveitis, Anterior

ArticleYear
Chronic Unilateral Uveitis as a Manifestation of Leprosy: A Case Report and Literature Review.
    Ocular immunology and inflammation, 2021, Aug-18, Volume: 29, Issue:6

    Topics: Aged; Atrophy; Biopsy; Chronic Disease; Clofazimine; Dapsone; Drug Therapy, Combination; Eye Infecti

2021

Other Studies

1 other study available for clofazimine and Uveitis, Anterior

ArticleYear
Management of reactions in leprosy.
    Journal of the Indian Medical Association, 1973, Nov-01, Volume: 61, Issue:9

    Topics: Adrenal Cortex Hormones; Clofazimine; Hand Deformities, Acquired; Humans; Leprosy; Neuritis; Skin Ul

1973