Page last updated: 2024-10-25

clofazimine and Sleep Apnea Syndromes

clofazimine has been researched along with Sleep Apnea Syndromes in 1 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.

Research Excerpts

ExcerptRelevanceReference
"Sarcoidosis is a chronic systemic granulomatous disease that occasionally affects the larynx."5.31Laryngeal sarcoidosis: treatment with the antileprosy drug clofazimine. ( Fradis, M; Golz, A; Löhle, E; Ridder, GJ; Strohhäcker, H, 2000)
"Sarcoidosis is a chronic systemic granulomatous disease that occasionally affects the larynx."1.31Laryngeal sarcoidosis: treatment with the antileprosy drug clofazimine. ( Fradis, M; Golz, A; Löhle, E; Ridder, GJ; Strohhäcker, H, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ridder, GJ1
Strohhäcker, H1
Löhle, E1
Golz, A1
Fradis, M1

Other Studies

1 other study available for clofazimine and Sleep Apnea Syndromes

ArticleYear
Laryngeal sarcoidosis: treatment with the antileprosy drug clofazimine.
    The Annals of otology, rhinology, and laryngology, 2000, Volume: 109, Issue:12 Pt 1

    Topics: Adult; Airway Obstruction; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy

2000
chemdatabank.com