Page last updated: 2024-10-25

clofazimine and Recrudescence

clofazimine has been researched along with Recrudescence in 45 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research Excerpts

ExcerptRelevanceReference
"Twenty patients, ten suffering from disseminated granuloma anulare and ten from necrobiosis lipoidica, were treated with clofazimine 200 mg p."7.67[Clofazimine--therapeutic alternative in necrobiosis lipoidica and granuloma anulare]. ( Mensing, H, 1989)
"This paper summarises our clinical experience with clofazimine in the treatment of 25 cases of reactive states of lepromatous and borderline leprosy and 7 lepromatous patients not responding to dapsone."7.65Clinical trial with clofazimine in leprosy. ( Dongre, VV; Ganapati, R, 1976)
"We conducted a randomized, open-label trial in 42 French hospitals to compare the clinical and bacteriologic efficacy of combination therapy with clarithromycin/clofazimine (Clm/Clof) with that of combination therapy with clarithromycin/rifabutin/ethambutol (Clm/Rib/Eth) as treatment for Mycobacterium avium bacteremia."5.08Comparison of combination therapy regimens for treatment of human immunodeficiency virus-infected patients with disseminated bacteremia due to Mycobacterium avium. ANRS Trial 033 Curavium Group. Agence Nationale de Recherche sur le Sida. ( Beuscart, C; Brel, F; Dautzenberg, B; Doco-Lecompte, T; Grosset, J; May, T; Perronne, C; Saint-Marc, T; Vincent, V, 1997)
"Between 1989 and 1993, 136 multibacillary leprosy patients received a 6-week treatment regimen consisting of daily rifampicin 600 mg, ofloxacin 400 mg, clofazimine 100 mg and a weekly dose of 100 mg minocycline."3.71Relapse rates and a 10-year follow-up of a 6-week quadruple drug regimen for multibacillary leprosy. ( Grillone, S; Pattyn, S, 2002)
"The proportion of relapses among all patients detected each year increased steadily since the initiation of the national leprosy control program in China with dapsone monotherapy in 1955, reaching 18%-24% in the more leprosy-endemic provinces along the coast."3.68Problems of leprosy relapse in China. ( Li, HY, 1993)
"Twenty patients, ten suffering from disseminated granuloma anulare and ten from necrobiosis lipoidica, were treated with clofazimine 200 mg p."3.67[Clofazimine--therapeutic alternative in necrobiosis lipoidica and granuloma anulare]. ( Mensing, H, 1989)
"Oral zinc sulfate was tried in Eight cases of recurrent Erythema Nodosum Leprosum."3.66Oral zinc in recurrent Erythema Nodosum Leprosum reaction. ( Bumb, RA; Mangal, HN; Mathur, NK, 1983)
" Reactive episodes continue to be a serious complication, but the availability of thalidomide to control erythema nodosum leprosum has markedly improved the prognosis."3.65The diagnosis and treatment of leprosy. ( Jacobson, RR; Trautman, JR, 1976)
"This paper summarises our clinical experience with clofazimine in the treatment of 25 cases of reactive states of lepromatous and borderline leprosy and 7 lepromatous patients not responding to dapsone."3.65Clinical trial with clofazimine in leprosy. ( Dongre, VV; Ganapati, R, 1976)
"No confirmed relapse has been observed within a follow-up period of 6 months to 7 years and 3 months [59 person-years at risk (PYR)] for TT/BT patients and of 4 months to 5 years and 10 months (100 PYR) for BB/BL/LL patients."2.68Daily multidrug therapy for leprosy; results of a fourteen-year experience. ( Cottenot, F; de Carsalade, GY; Flageul, B; Pennec, J; Spindler, E; Wallach, D, 1997)
"Relapses are an indicator of MDT effectiveness and can reflect Mycobacterium leprae persistence or re-infection."1.62Low rate of relapse after twelve-dose multidrug therapy for hansen's disease: A 20-year cohort study in a brazilian reference center. ( Hacker, MAVB; Illarramendi, X; Maia, RC; Moraes, MO; Nery, JAC; Sales, AM; Sarno, EN, 2021)
"Mice treated with clofazimine were culture-negative after 5 months, whereas all mice treated without clofazimine remained heavily culture-positive for the entire 9 months of the study."1.39Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice. ( Almeida, DV; Ammerman, NC; Bishai, WR; Converse, PJ; Enarson, D; Grosset, JH; Li, SY; Trébucq, A; Tyagi, S, 2013)
"Leprosy is well controlled in Hong Kong but continued surveillance is required to detect relapses and to ensure good patient compliance with treatment."1.33Epidemiology of leprosy and response to treatment in Hong Kong. ( Ho, CK; Lo, KK, 2006)
"Areas of low endemicity of Hansen's disease, such as Texas, California, and Hawaii, exist due to immigration and rare autochthonous infections."1.32Short report: Treatment failure in Hansen's disease. ( Joyce, MP; Longfield, RN; Murray, CK, 2003)
"Th rate of recurrence of pyoderma gangrenosum was 46% independently of treatment."1.31[Pyoderma gangrenosum. 15 cases]. ( Azaiz, MI; Ben Osman-Dhahri, A; Cherif, F; El Euch, D; Haouet, S; Mokni, M; Riahi, I; Zitouna, MM, 2001)
"Pustular lesions are known to occur in Sweet's syndrome."1.29[Idiopathic pustular and bullous variants of Sweet syndrome]. ( Albrecht, HP; Diepgen, TL; Tacke, J; von den Driesch, P, 1994)
" The initial dosage of either of the drugs was 300 mg daily administered in divided doses of 100 mg three times a day."1.26Treatment of steroid dependant cases of recurrent lepra reaction with a combination of thalidomide and clofazimine. ( Girdhar, A; Ramu, G, 1979)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199015 (33.33)18.7374
1990's12 (26.67)18.2507
2000's10 (22.22)29.6817
2010's6 (13.33)24.3611
2020's2 (4.44)2.80

Authors

AuthorsStudies
Yu, W1
Chiwala, G1
Gao, Y1
Liu, Z1
Sapkota, S1
Lu, Z1
Guo, L1
Khan, SA1
Zhong, N1
Zhang, T1
Nery, JAC1
Sales, AM1
Hacker, MAVB1
Moraes, MO1
Maia, RC1
Sarno, EN1
Illarramendi, X1
Penna, GO1
Bührer-Sékula, S1
Kerr, LRS1
Stefani, MMA1
Rodrigues, LC1
de Araújo, MG1
Ramos, AMC1
de Andrade, ARC1
Costa, MB1
Rosa, PS1
Gonçalves, HS1
Cruz, R1
Barreto, ML1
Pontes, MAA1
Penna, MLF1
Ahmad, N1
Ahuja, SD1
Akkerman, OW1
Alffenaar, JC1
Anderson, LF1
Baghaei, P1
Bang, D1
Barry, PM1
Bastos, ML1
Behera, D1
Benedetti, A1
Bisson, GP1
Boeree, MJ1
Bonnet, M1
Brode, SK1
Brust, JCM1
Cai, Y1
Caumes, E1
Cegielski, JP1
Centis, R1
Chan, PC1
Chan, ED1
Chang, KC1
Charles, M1
Cirule, A1
Dalcolmo, MP1
D'Ambrosio, L1
de Vries, G1
Dheda, K1
Esmail, A1
Flood, J1
Fox, GJ1
Fréchet-Jachym, M1
Fregona, G1
Gayoso, R1
Gegia, M1
Gler, MT1
Gu, S1
Guglielmetti, L1
Holtz, TH1
Hughes, J1
Isaakidis, P1
Jarlsberg, L1
Kempker, RR1
Keshavjee, S1
Khan, FA1
Kipiani, M1
Koenig, SP1
Koh, WJ1
Kritski, A1
Kuksa, L1
Kvasnovsky, CL1
Kwak, N1
Lan, Z1
Lange, C1
Laniado-Laborín, R1
Lee, M1
Leimane, V1
Leung, CC1
Leung, EC1
Li, PZ1
Lowenthal, P1
Maciel, EL1
Marks, SM1
Mase, S1
Mbuagbaw, L1
Migliori, GB1
Milanov, V1
Miller, AC1
Mitnick, CD1
Modongo, C1
Mohr, E1
Monedero, I1
Nahid, P1
Ndjeka, N1
O'Donnell, MR1
Padayatchi, N1
Palmero, D1
Pape, JW1
Podewils, LJ1
Reynolds, I1
Riekstina, V1
Robert, J1
Rodriguez, M1
Seaworth, B1
Seung, KJ1
Schnippel, K1
Shim, TS1
Singla, R1
Smith, SE1
Sotgiu, G1
Sukhbaatar, G1
Tabarsi, P1
Tiberi, S1
Trajman, A1
Trieu, L1
Udwadia, ZF1
van der Werf, TS1
Veziris, N1
Viiklepp, P1
Vilbrun, SC1
Walsh, K1
Westenhouse, J1
Yew, WW1
Yim, JJ1
Zetola, NM1
Zignol, M1
Menzies, D1
Grosset, JH1
Tyagi, S1
Almeida, DV1
Converse, PJ1
Li, SY1
Ammerman, NC1
Bishai, WR1
Enarson, D1
Trébucq, A1
Patton, PH1
Parker, CE1
MacDonald, JK1
Chande, N1
Maghanoy, A1
Mallari, I1
Balagon, M2
Saunderson, P1
Saunderson, PR1
Gelber, RH1
Pattyn, S1
Grillone, S1
Murray, CK1
Joyce, MP1
Longfield, RN1
Schreuder, PA1
Naafs, B1
Norman, G1
Joseph, G1
Richard, J1
Armour, KS1
Scolyer, RA1
Barnetson, RS1
Ho, CK1
Lo, KK1
Nenoff, P1
Uhlemann, R1
Grünewald, T1
Nenning, H1
Grunewald, S1
Paasch, U1
Levy, L1
Mathur, NK1
Bumb, RA1
Mangal, HN1
Bentley-Phillips, CB1
Cooper, RC1
Hallett, AF1
Kemper, CA1
Havlir, D1
Bartok, AE1
Kane, C1
Camp, B1
Lane, N1
Deresinski, SC1
Dautzenberg, B2
Saint-Marc, T2
Durant, J1
Reynes, J1
Meyohas, MC1
Legrand, MF1
Truffot, C1
Chauvin, JP1
Tacke, J1
Diepgen, TL1
Albrecht, HP1
von den Driesch, P1
Pattyn, SR2
Ghys, P1
Janssens, L1
Tshilumba, K1
Kuykens, L1
Karibushi, N1
Denis, P1
Li, HY1
Wollina, U1
Karte, K1
Geyer, A1
Stuhlert, A1
Bocker, T1
de Carsalade, GY1
Wallach, D2
Spindler, E1
Pennec, J2
Cottenot, F2
Flageul, B2
May, T1
Brel, F1
Beuscart, C1
Vincent, V1
Perronne, C1
Doco-Lecompte, T1
Grosset, J1
Shaw, IN2
Ebenezer, G1
Rao, GS2
Natrajan, MM2
Balasundaram, B1
Riahi, I1
Mokni, M1
Haouet, S1
Cherif, F1
El Euch, D1
Azaiz, MI1
Zitouna, MM1
Ben Osman-Dhahri, A1
Jesudasan, K1
Christian, M1
Kavitha, M1
Faber, WR1
Leiker, DL2
Ramu, G2
Girdhar, A1
Jacobson, RR1
Trautman, JR1
Iyer, CG1
Ganapati, R1
Dongre, VV1
Becx-Bleumink, M1
Blok, LM1
Bloos, LJ1
van den Berg, G1
Afdhal, NH1
Long, A1
Lennon, J1
Crowe, J1
O'Donoghue, DP1
Vignon-Pennamen, MD1
Mensing, H1
Ekambaram, V1
Rao, MK1
Rao, CK1
Mittal, BN1
Dharmshaktu, NS1
Onsun, N1
Saylan, T1
Revill, WD1
Morrow, RH1
Pike, MC1
Ateng, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Independent Study to Establish the Efficacy of the Six Doses Uniform MDT Regimen (U-MDT) for Leprosy Patients[NCT00669643]Phase 4859 participants (Actual)Interventional2007-02-28Completed
Effect of Vitamin D3 Supplementation on Chronic Granulomatous Disease Patients With BCGosis/Itis[NCT03984890]Phase 2/Phase 350 participants (Anticipated)Interventional2019-08-01Recruiting
Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy: Comparison of 8 Weeks Standard Therapy (Rifampicin Plus Clarithromycin) vs. 4 Weeks Standard Plus Amoxicillin/Clavulanate Therapy [RC8 vs. RCA4][NCT05169554]Phase 2140 participants (Anticipated)Interventional2021-12-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for clofazimine and Recrudescence

ArticleYear
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.
    Lancet (London, England), 2018, 09-08, Volume: 392, Issue:10150

    Topics: Amikacin; Antitubercular Agents; Capreomycin; Carbapenems; Clofazimine; Diarylquinolines; Drug Thera

2018
Anti-tuberculous therapy for maintenance of remission in Crohn's disease.
    The Cochrane database of systematic reviews, 2016, Jul-22, Volume: 7

    Topics: Antitubercular Agents; Clarithromycin; Clofazimine; Crohn Disease; Ethambutol; Glucocorticoids; Huma

2016
Evolution of the modern chemotherapy of leprosy.
    Leprosy review, 1983, Volume: Spec No

    Topics: Animals; Clofazimine; Dapsone; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance, Micro

1983
Relapses among leprosy patients treated with multidrug therapy: experience in the leprosy control program of the All Africa Leprosy and Rehabilitation Training Center (ALERT) in Ethiopia; practical difficulties with diagnosing relapses; operational proced
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1992, Volume: 60, Issue:3

    Topics: Clofazimine; Dapsone; Epidemiologic Methods; Ethiopia; Humans; Incidence; Leprostatic Agents; Lepros

1992

Trials

11 trials available for clofazimine and Recrudescence

ArticleYear
Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): Results of an open label, randomized and controlled clinical trial, among multibacillary patients.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brazil; Child; Child, Preschool; Clofazimine; Dapsone; D

2017
Relapses in multibacillary patients treated with multi-drug therapy until smear negativity: findings after twenty years.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2004, Volume: 72, Issue:1

    Topics: Acedapsone; Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Follow-Up Studies; Humans

2004
Transient bacteremia due to Mycobacterium avium complex in patients with AIDS.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Bacteremia; Clofazimine; Drug Therapy, Combination; Et

1994
[Treatment with clarithromycin of 173 HIV+ patients with disseminated Mycobacterium avium intracellulare infection].
    Revue des maladies respiratoires, 1994, Volume: 11, Issue:3

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agen

1994
A randomized clinical trial of two single-dose treatments for paucibacillary leprosy.
    Leprosy review, 1994, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clofazimine; Dapsone; Drug Administration Schedule

1994
Daily multidrug therapy for leprosy; results of a fourteen-year experience.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1997, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clofazimine; Dapsone; Drug Resistance, Microbial;

1997
Comparison of combination therapy regimens for treatment of human immunodeficiency virus-infected patients with disseminated bacteremia due to Mycobacterium avium. ANRS Trial 033 Curavium Group. Agence Nationale de Recherche sur le Sida.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Bacteremia; Clarithromycin; Clofazimine; Drug Therapy,

1997
Long-term follow up of multibacillary leprosy patients with high BI treated with WHO/MDT regimen for a fixed duration of two years.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2000, Volume: 68, Issue:4

    Topics: Adult; Clofazimine; Cohort Studies; Dapsone; Drug Therapy, Combination; Female; Follow-Up Studies; H

2000
Evaluation of treatment of lepromatous leprosy patients in the Netherlands.
    Dermatologica, 1979, Volume: 158, Issue:1

    Topics: Clinical Trials as Topic; Clofazimine; Dapsone; Drug Evaluation; Humans; Leprostatic Agents; Leprosy

1979
Controlled trial of antimycobacterial therapy in Crohn's disease. Clofazimine versus placebo.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:4

    Topics: Adult; Clofazimine; Crohn Disease; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middl

1991
A controlled trial of the treatment of Mycobacterium ulcerans infection with clofazimine.
    Lancet (London, England), 1973, Oct-20, Volume: 2, Issue:7834

    Topics: Clinical Trials as Topic; Clofazimine; Culture Media; Drug Evaluation; Humans; Mycobacterium; Mycoba

1973

Other Studies

30 other studies available for clofazimine and Recrudescence

ArticleYear
TB47 and clofazimine form a highly synergistic sterilizing block in a second-line regimen for tuberculosis in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 131

    Topics: Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Drug Synergism; Female; Imidazo

2020
Low rate of relapse after twelve-dose multidrug therapy for hansen's disease: A 20-year cohort study in a brazilian reference center.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brazil; Child; Child, Preschool; Clofazimine; Dapsone; D

2021
Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice.
    American journal of respiratory and critical care medicine, 2013, Sep-01, Volume: 188, Issue:5

    Topics: Animals; Antitubercular Agents; Clofazimine; Drug Resistance, Multiple, Bacterial; Female; Lung; Mic

2013
Relapse study in smear positive multibacillary (MB) leprosy after 1 year WHO-multi-drug therapy (MDT) in Cebu, Philippines.
    Leprosy review, 2011, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Lep

2011
Does clofazimine prevent erythema nodosum leprosum (ENL) in leprosy? A retrospective study, comparing the experience of multibacillary patients receiving either 12 or 24 months WHO-MDT.
    Leprosy review, 2011, Volume: 82, Issue:3

    Topics: Adolescent; Adult; Age Distribution; Aged; Child; Clofazimine; Drug Therapy, Combination; Erythema N

2011
Relapse rates and a 10-year follow-up of a 6-week quadruple drug regimen for multibacillary leprosy.
    Leprosy review, 2002, Volume: 73, Issue:3

    Topics: Belgium; Clofazimine; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Hu

2002
Short report: Treatment failure in Hansen's disease.
    The American journal of tropical medicine and hygiene, 2003, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Lep

2003
Chronic recurrent ENL, steroid dependent: long-term treatment with high dose clofazimine.
    Leprosy review, 2003, Volume: 74, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clofazimine; Dose-Response Relationship, D

2003
Borderline lepromatous leprosy presenting as a single cutaneous plaque.
    The Australasian journal of dermatology, 2005, Volume: 46, Issue:3

    Topics: Administration, Oral; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Forearm; Glucocorticoi

2005
Epidemiology of leprosy and response to treatment in Hong Kong.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2006, Volume: 12, Issue:3

    Topics: Clofazimine; Dapsone; Drug Resistance, Bacterial; Drug Therapy, Combination; Hong Kong; Humans; Inci

2006
[Atypical mycobacteriosis of the skin caused by Mycobacterium abscessus in an immunocompetent woman].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2007, Volume: 58, Issue:12

    Topics: Antitubercular Agents; Biopsy; Buruli Ulcer; Clofazimine; Drug Therapy, Combination; Female; Follow-

2007
Oral zinc in recurrent Erythema Nodosum Leprosum reaction.
    Leprosy in India, 1983, Volume: 55, Issue:3

    Topics: Administration, Oral; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Erythema Nodosum; Fema

1983
Pharmacological modulation of neutrophil phagocytic function in a patient with recurrent sepsis, pyoderma gangrenosum and impaired phagocytosis.
    The British journal of dermatology, 1982, Volume: 106, Issue:6

    Topics: Adrenal Cortex Hormones; Bacterial Infections; Clofazimine; Humans; In Vitro Techniques; Levamisole;

1982
[Idiopathic pustular and bullous variants of Sweet syndrome].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1994, Volume: 45, Issue:3

    Topics: Biopsy; Clofazimine; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration

1994
Problems of leprosy relapse in China.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1993, Volume: 61, Issue:1

    Topics: China; Clofazimine; Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Leprosy; Recurren

1993
Clofazimine in inflammatory facial dermatosis--granuloma faciale and lipogranulomatosis subcutanea (Rothmann-Makai)
    Acta dermato-venereologica, 1996, Volume: 76, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Disease Progression; Facial Dermatoses;

1996
Relapse as histoid leprosy after receiving multidrug therapy (MDT); a report of three cases.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2000, Volume: 68, Issue:3

    Topics: Acedapsone; Adolescent; Adult; Animals; Child; Clofazimine; Dapsone; Drug Resistance, Microbial; Dru

2000
[Pyoderma gangrenosum. 15 cases].
    Annales de medecine interne, 2001, Volume: 152, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Child,

2001
Workshop on "chemotherapy of leprosy" at the Central Leprosy Teaching and Research Institute, Chengalpattu (Tamil Nadu) on 21 January 1978.
    Leprosy in India, 1979, Volume: 51, Issue:1

    Topics: Clofazimine; Dapsone; Humans; India; Leprosy; Recurrence; Rifampin; Thalidomide

1979
Treatment of steroid dependant cases of recurrent lepra reaction with a combination of thalidomide and clofazimine.
    Leprosy in India, 1979, Volume: 51, Issue:4

    Topics: Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Male; Recurrence; Steroids;

1979
The diagnosis and treatment of leprosy.
    Southern medical journal, 1976, Volume: 69, Issue:8

    Topics: Biopsy; Clofazimine; Dapsone; Erythema Nodosum; Humans; Immunotherapy; Leprosy; Recurrence; Rifampin

1976
An open trial with clofazimine in the management of recurrent lepra reaction using thalidomide as a control drug.
    Leprosy in India, 1976, Volume: 48, Issue:4 Suppl

    Topics: Adolescent; Adult; Clofazimine; Humans; Leprosy; Male; Middle Aged; Recurrence; Thalidomide

1976
Clinical trial with clofazimine in leprosy.
    Leprosy in India, 1976, Volume: 48, Issue:4 Suppl

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination;

1976
A retrospective study on seven years of multiple drug treatment for paucibacillary and multibacillary leprosy, in Bayara General Hospital, Nigeria.
    Leprosy review, 1991, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; D

1991
[Late reversal reactions in leprosy].
    Acta leprologica, 1990, Volume: 7, Issue:2

    Topics: Clofazimine; Dapsone; Drug Combinations; Ethionamide; Female; Humans; Leprosy; Male; Recurrence; Rif

1990
[Clofazimine--therapeutic alternative in necrobiosis lipoidica and granuloma anulare].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1989, Volume: 40, Issue:2

    Topics: Administration, Oral; Adult; Clofazimine; Drug Administration Schedule; Female; Granuloma; Humans; M

1989
Changing picture of leprosy in North Arcot District, Tamil Nadu after M.D.T.
    Indian journal of leprosy, 1989, Volume: 61, Issue:1

    Topics: Clofazimine; Cohort Studies; Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; India; L

1989
Leprosy control based on multi drug treatment in India.
    Indian journal of leprosy, 1988, Volume: 60, Issue:2

    Topics: Allied Health Personnel; Clofazimine; Dapsone; Data Collection; Drug Administration Schedule; Drug T

1988
Combined chemotherapy of multibacillary leprosy of 6 months' duration.
    Leprosy review, 1986, Volume: 57 Suppl 3

    Topics: Adolescent; Adult; Child; Child, Preschool; Clofazimine; Dapsone; Drug Therapy, Combination; Female;

1986
Preliminary results of treatment of leprosy patients in The Netherlands with daily rifampicin, dapsone and clofazimine.
    Leprosy review, 1986, Volume: 57 Suppl 3

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Netherlands; Recurrence; Rifampin

1986