clofazimine has been researched along with Pyoderma Gangrenosum in 7 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Pyoderma Gangrenosum: An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of pyoderma gangrenosum in a 80-year-old woman suffering from ulcerative colitis and treated with clofazimine." | 7.68 | Treatment of pyoderma gangrenosum with clofazimine. ( Feinstein, A; Kaplan, B; Schewach-Millet, M; Sofer, E; Trau, H, 1992) |
| "We report a case of pyoderma gangrenosum in a 80-year-old woman suffering from ulcerative colitis and treated with clofazimine." | 3.68 | Treatment of pyoderma gangrenosum with clofazimine. ( Feinstein, A; Kaplan, B; Schewach-Millet, M; Sofer, E; Trau, H, 1992) |
| "Th rate of recurrence of pyoderma gangrenosum was 46% independently of treatment." | 1.31 | [Pyoderma gangrenosum. 15 cases]. ( Azaiz, MI; Ben Osman-Dhahri, A; Cherif, F; El Euch, D; Haouet, S; Mokni, M; Riahi, I; Zitouna, MM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| di Meo, N | 1 |
| Fluehler, C | 1 |
| Perkan, V | 1 |
| Trevisan, G | 1 |
| Pari, T | 1 |
| George, S | 1 |
| Jacob, M | 1 |
| Chandi, SM | 1 |
| Pulimood, S | 1 |
| Rajagopalan, B | 1 |
| Erdi, H | 1 |
| Anadolu, R | 1 |
| Pişkin, G | 1 |
| Gürgey, E | 1 |
| Bröcker, EB | 1 |
| Ludwig, G | 1 |
| Riahi, I | 2 |
| Mokni, M | 2 |
| Haouet, S | 1 |
| Cherif, F | 1 |
| El Euch, D | 1 |
| Azaiz, MI | 1 |
| Zitouna, MM | 1 |
| Ben Osman-Dhahri, A | 1 |
| Mlika, RB | 1 |
| Fenniche, S | 1 |
| Dhaoui, MR | 1 |
| Dess, N | 1 |
| Dhahri, AB | 1 |
| Mokhtar, I | 1 |
| Kaplan, B | 1 |
| Trau, H | 1 |
| Sofer, E | 1 |
| Feinstein, A | 1 |
| Schewach-Millet, M | 1 |
1 review available for clofazimine and Pyoderma Gangrenosum
| Article | Year |
|---|---|
Pyoderma gangrenosum: a report of 21 cases.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-S | 2002 |
6 other studies available for clofazimine and Pyoderma Gangrenosum
| Article | Year |
|---|---|
Disseminated superficial porokeratosis and pyoderma gangrenosum.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-St | 2010 |
Malignant pyoderma responding to clofazimine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Female; Humans; Pyoderma Gangrenosum | 1996 |
Malignant pyoderma: a clinical variant of pyoderma gangrenosum.
Topics: Adrenal Cortex Hormones; Adult; Clofazimine; Dapsone; Female; Folliculitis; Humans; Pyoderma Gangren | 1996 |
[Pyoderma gangraenosum].
Topics: Adrenal Cortex Hormones; Clofazimine; Humans; Immunosuppressive Agents; Pyoderma Gangrenosum; Skin; | 1996 |
[Pyoderma gangrenosum. 15 cases].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, | 2001 |
Treatment of pyoderma gangrenosum with clofazimine.
Topics: Aged; Aged, 80 and over; Clofazimine; Colitis, Ulcerative; Female; Humans; Pyoderma Gangrenosum | 1992 |