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clofazimine and Prurigo

clofazimine has been researched along with Prurigo in 2 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Prurigo: A name applied to several itchy skin eruptions of unknown cause. The characteristic course is the formation of a dome-shaped papule with a small transient vesicle on top, followed by crusting over or lichenification. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"A 46-year-old woman with widespread prurigo nodularis was treated with 300 mg clofazimine a day for six months."7.66Small bowel deposition of crystals associated with the use of clofazimine (Lamprene) in the treatment of prurigo nodularis. ( Belaube, P; Boutboul, R; Devaux, J; Pizzi, M; Privat, Y, 1983)
"A 46-year-old woman with widespread prurigo nodularis was treated with 300 mg clofazimine a day for six months."3.66Small bowel deposition of crystals associated with the use of clofazimine (Lamprene) in the treatment of prurigo nodularis. ( Belaube, P; Boutboul, R; Devaux, J; Pizzi, M; Privat, Y, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belaube, P2
Devaux, J2
Pizzi, M2
Boutboul, R2
Privat, Y2
Galland, MC1

Other Studies

2 other studies available for clofazimine and Prurigo

ArticleYear
Small bowel deposition of crystals associated with the use of clofazimine (Lamprene) in the treatment of prurigo nodularis.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1983, Volume: 51, Issue:3

    Topics: Clofazimine; Crystallization; Female; Humans; Intestinal Diseases; Middle Aged; Prurigo

1983
[Deposits of crystals in the mucous membrane of the small intestine during treatment with clofazimine].
    Annales de dermatologie et de venereologie, 1982, Volume: 109, Issue:6-7

    Topics: Celiac Disease; Clofazimine; Crystallization; Female; Humans; Intestinal Diseases; Intestinal Mucosa

1982