clofazimine has been researched along with Peripheral Nerve Diseases in 11 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diagnosis of leprosy is frequently not considered, with resultant pathological and psychological problems for patients." | 2.41 | Update on leprosy. ( Lockwood, DN; Marlowe, SN, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Saroha, D | 1 |
| Garg, D | 1 |
| Singh, AK | 1 |
| Dhamija, RK | 1 |
| Flores-Suárez, LF | 1 |
| Fernández-Sánchez, M | 1 |
| Ahumada-Topete, VH | 1 |
| Rodríguez, M | 1 |
| Charli-Joseph, Y | 1 |
| Mirfazaelian, H | 1 |
| Eilami, O | 1 |
| Afzalimoghadam, M | 1 |
| Daneshbod, Y | 1 |
| Bharucha, T | 1 |
| Lockwood, D | 1 |
| Sheetal, S | 1 |
| Arvind, C | 1 |
| Jardim, MR | 1 |
| Illarramendi, X | 1 |
| Nascimento, OJ | 1 |
| Nery, JA | 1 |
| Sales, AM | 1 |
| Sampaio, EP | 1 |
| Sarno, EN | 1 |
| McDougall, AC | 1 |
| Jones, RL | 1 |
| Naafs, B | 1 |
| Marlowe, SN | 1 |
| Lockwood, DN | 1 |
| Hentschel, B | 1 |
| Pfaltzgraff, RE | 1 |
2 reviews available for clofazimine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Bangkok Workshop on Leprosy Research. Treatment of reactions and nerve damage.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Cyclosporine; Drug A | 1996 |
Update on leprosy.
Topics: Clofazimine; Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Leprostatic Agents | 2001 |
9 other studies available for clofazimine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum.
Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Clofazimine; Cycloserine; Deprescriptions; Diaryl | 2020 |
After all, still a magnificent impersonator.
Topics: Adult; Biopsy; Clofazimine; Diagnostic Errors; Female; Humans; Leprostatic Agents; Mycobacterium; My | 2021 |
A man with facial changes.
Topics: Clofazimine; Dapsone; Facies; Humans; Leprostatic Agents; Leprosy, Lepromatous; Male; Mycobacterium | 2014 |
Leprosy in the UK.
Topics: Clofazimine; Dapsone; Humans; Leprostatic Agents; Leprosy; Peripheral Nervous System Diseases; Rifam | 2016 |
Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience.
Topics: Acute Disease; Aged; Arthritis; Clofazimine; Dapsone; Diagnosis, Differential; Drug Therapy, Combina | 2009 |
Pure neural leprosy: steroids prevent neuropathy progression.
Topics: Adult; Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Electrophysiology; Female; Follow-Up S | 2007 |
Intra-neural ceroid-like pigment following the treatment of lepromatous leprosy with clofazimine (B663; Lamprene).
Topics: Adult; Ceroid; Clofazimine; Dapsone; Drug Therapy, Combination; Histocytochemistry; Humans; Leprosy; | 1981 |
[Leprosy and the nervous system (author's transl)].
Topics: Adult; Antibody Formation; Central Nervous System Diseases; Clofazimine; Dapsone; Diagnosis, Differe | 1979 |
Bilateral ulnar nerve abscesses in lepromatous leprosy.
Topics: Abscess; Clofazimine; Humans; Leprosy; Peripheral Nervous System Diseases; Ulnar Nerve | 1987 |